3-Hydroxy-5-(trifluoromethyl)benzoic acid
- CAS No.
- 328-69-8
- Chemical Name:
- 3-Hydroxy-5-(trifluoromethyl)benzoic acid
- Synonyms
- -Carboxy-5-(trifluoromethyl)phenol;3-Hydroxy-5-(trifluoromethyl)benzoic acid;Benzoic acid, 3-hydroxy-5-(trifluoromethyl)-;3-Carboxy-5-(trifluoromethyl)phenol, 3-Carboxy-5-hydroxybenzotrifluoride
- CBNumber:
- CB7171006
- Molecular Formula:
- C8H5F3O3
- Molecular Weight:
- 206.12
- MDL Number:
- MFCD07368783
- MOL File:
- 328-69-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2918290090 | |||||||||
| NFPA 704 |
|
3-Hydroxy-5-(trifluoromethyl)benzoic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC9912 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid ≥95% | 328-69-8 | 500mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | PC9912 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid ≥95% | 328-69-8 | 1g | $33 | 2026-06-04 | Buy |
| Apolloscientific | PC9912 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid ≥95% | 328-69-8 | 5g | $130 | 2026-06-04 | Buy |
| Apolloscientific | PC9912 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid ≥95% | 328-69-8 | 10g | $218 | 2026-06-04 | Buy |
| Activate Scientific | AS38554 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid 97% | 328-69-8 | 1g | $25 | 2026-06-04 | Buy |
3-Hydroxy-5-(trifluoromethyl)benzoic acid Chemical Properties, Uses, Production
Synthesis
328-68-7
328-69-8
Step 2: To an aqueous suspension of 3-amino-5-trifluoromethylbenzoic acid (4.36 g, 21.3 mmol) was slowly added concentrated sulfuric acid (10.6 mL, 191 mmol) at 0 °C. The reaction mixture was stirred continuously until the solid was completely dissolved. Subsequently, an aqueous solution (40 mL) of sodium nitrite (1.47 g, 21.3 mmol) was added dropwise. The reaction mixture was continued to be stirred at 0 °C for 15 min, and then warmed up to reflux state maintained for 15 min. Upon completion of the reaction, the mixture was cooled to room temperature and extracted three times with ether. All organic layers were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give 3-hydroxy-5-(trifluoromethyl)benzoic acid (25-2, 4.06 g) as a yellow solid.
References
[1] Patent: WO2007/64045, 2007, A1. Location in patent: Page/Page column 341-342
[2] Patent: US2018/312523, 2018, A1. Location in patent: Paragraph 1842; 1844
3-Hydroxy-5-(trifluoromethyl)benzoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3828 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
View Latest Price from 3-Hydroxy-5-(trifluoromethyl)benzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-22 | 3-Hydroxy-5-(trifluoromethyl)benzoic acid
328-69-8
|
1KG | 97.0% | 100 tons | Honest Joy Holdings Limited |
-
- 3-Hydroxy-5-(trifluoromethyl)benzoic acid
328-69-8
- $0.00
- 97.0%
- Honest Joy Holdings Limited
