(2R,3S)-N-Benzoyl-3-phenyl Isoserine

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Suppliers list

Company Name:	Beijing HwrkChemical Technology Co., Ltd
Tel:	89508211 18501085097
Email:	sales.bj@hwrkchemical.com

Company Name:	Chemsky（shanghai）International Co.,Ltd.
Tel:	021-50135380
Email:	shchemsky@sina.com

(2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Basic information

Product Name:	(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonyms:	N-BENZOYL-(2R,3S)-3-AMINO-2-HYDROXY-3-PHENYL-PROPIONIC ACID;TAXOL(R) SIDE CHAIN;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionacid;Taxol side chain alcohol;(2R, 3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONACID,98+%;(2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid;SIDE CHAINS OF PACLITAXEL--4
CAS:	132201-33-3
MF:	C16H15NO4
MW:	285.3
EINECS:	631-348-7
Product Categories:	Herb extract;Serine Derivatives;Peptide Synthesis;Unnatural Amino Acid Derivatives;Amino Acids & Derivatives;Anti-virals;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	132201-33-3.mol

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties

Melting point	169-172 °C (lit.)
Boiling point	580.7±50.0 °C(Predicted)
density	1.316±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
form	Solid
pka	3.40±0.17(Predicted)
color	White to Off-White
Optical Rotation	[α]20/D 40°, c = 1.0 in ethanol
Major Application	peptide synthesis
InChI	1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1
InChIKey	HYJVYOWKYPNSTK-UONOGXRCSA-N
SMILES	O[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O
CAS DataBase Reference	132201-33-3(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Usage And Synthesis

Chemical Properties	White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.
Uses	(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.
Uses	The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.
reaction suitability	reaction type: solution phase peptide synthesis

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials

Tag:(2R,3S)-N-Benzoyl-3-phenyl Isoserine(132201-33-3) Related Product Information

Benzoyl peroxide L-Homoserine 3-(4-Hydroxyphenyl)propionic acid Folic acid Benzoyl chloride Ethyl 2-(Chlorosulfonyl)acetate D-Cycloserine L(+)-Lactic acid β-Alanine DL-Serine N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE METHYL ESTER 7-Epitaxol Citric acid Chlorophosphonazo III 3,4'-Diaminodiphenylmethane L-alpha-Phosphatidylserines, brain, bovine Benzoyl isocyanate 10-Deacetylbaccatin III