6-Methyl-2,2'-bipyridine
- CAS No.
- 56100-22-2
- Chemical Name:
- 6-Methyl-2,2'-bipyridine
- Synonyms
- 6-METHYL-2,2'-DIPYRIDYL;6-Methyl-2,2'-bipyridine;6-Methyl-2,2 '- Dipyridine;2,2'-Bipyridine, 6-Methyl-;6-Methyl-2,2'-dipyridyl 97%;6-methyl-2-(2-pyridyl)pyridine;2-methyl-6-(pyridin-2-yl)pyridine
- CBNumber:
- CB7241622
- Molecular Formula:
- C11H10N2
- Molecular Weight:
- 170.21
- MDL Number:
- MFCD02093688
- MOL File:
- 56100-22-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 117-119 °C0.1 mm Hg(lit.) |
|---|---|
| Density | 1.09 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 4.82±0.10(Predicted) |
| Appearance | Yellow to brown Solid-Liquid Mixture |
| InChI | 1S/C11H10N2/c1-9-5-4-7-11(13-9)10-6-2-3-8-12-10/h2-8H,1H3 |
| InChIKey | LLCYXFYLGPOKQO-UHFFFAOYSA-N |
| SMILES | Cc1cccc(n1)-c2ccccn2 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
6-Methyl-2,2'-bipyridine price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS140563 | 6-Methyl-2,2'-bipyridine 98% | 56100-22-2 | 1g | $132 | 2026-06-04 | Buy |
| Activate Scientific | AS140563 | 6-Methyl-2,2'-bipyridine 98% | 56100-22-2 | 5g | $502 | 2026-06-04 | Buy |
| Synthonix | M54263 | 6-Methyl-2,2'-bipyridine 98% | 56100-22-2 | 100mg | $30 | 2026-05-06 | Buy |
| Synthonix | M54263 | 6-Methyl-2,2'-bipyridine 98% | 56100-22-2 | 250mg | $36 | 2026-05-06 | Buy |
| Synthonix | M54263 | 6-Methyl-2,2'-bipyridine 98% | 56100-22-2 | 1g | $80 | 2026-05-06 | Buy |
6-Methyl-2,2'-bipyridine Chemical Properties, Uses, Production
Synthesis
366-18-7
917-54-4
56100-22-2
A tetrahydrofuran (26 mL) solution of methyl lithium (1.3 M, 33.80 mmol) was slowly added dropwise to an ethyl ether (100 mL) solution of 2,2'-bipyridine (5.30 g, 34.00 mmol) at 0°C and under nitrogen protection. The reaction mixture was stirred at this temperature for 2 hours and then refluxed at elevated temperature for 3 hours. When the reaction solution was cooled to room temperature, the reaction was quenched by the addition of water (10 mL). The organic phase was separated and the aqueous phase was extracted with ether three times. The organic phases were combined and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give an orange colored oil. This oily material was dissolved in acetone solution saturated with potassium permanganate (300 mL) and stirred at room temperature for 1 hour for oxidation reaction. The filtrate was filtered and concentrated to remove the acetone. The residue was purified by vacuum distillation to afford the colorless oily target product 6-methyl-2,2'-bipyridine (3.73 g, 63.8% yield). The structure of the product was confirmed by nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 400MHz, CDCl3), carbon spectroscopy (13C NMR, 100MHz, CDCl3) and electrospray ionization mass spectrometry (ESI-MS): 1H NMR δ 8.65 (s, 1H), 8.38 (d, J = 8.0 Hz, 1H), 8.15 (d, J = 7.9 Hz, 1H), 7.72-7.82 (d, J = 7.9 Hz, 1H), 8.15 (d, J = 7.9 Hz, 1H) 7.72-7.82 (m, 1H), 7.66 (d, J = 7.7 Hz, 1H), 7.21-7.30 (m, 1H), 7.13 (d, J = 7.7 Hz, 1H), 2.61 (s, 3H); 13C NMR δ 157.7, 156.3, 155.4, 149.0, 136.9, 136.7, 123.6, 123.2, 121.02, 117.9, 24.5; ESI-MS m/z: [M+H]+ measured value 171.61 (calculated value 171.22).
References
[1] Angewandte Chemie - International Edition, 2014, vol. 53, # 23, p. 5872 - 5876
[2] Dyes and Pigments, 2016, vol. 128, p. 33 - 40
[3] Patent: CN105669689, 2016, A. Location in patent: Paragraph 0032
[4] Angewandte Chemie - International Edition, 2016, vol. 55, # 37, p. 11207 - 11211
[5] Angew. Chem., 2016, vol. 128, # 37, p. 11373 - 11377,5
6-Methyl-2,2'-bipyridine Preparation Products And Raw materials
Raw materials
Preparation Products
6-Methyl-2,2'-bipyridine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Hangzhou Milestone Pharmtech Co., Ltd. | 0571-82896630 18969958410 | sales_hz@milestonepharmtech.com | China | 4907 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
View Latest Price from 6-Methyl-2,2'-bipyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-08 | 6-METHYL-2,2'-BIPYRIDINE
56100-22-2
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 6-METHYL-2,2'-BIPYRIDINE
56100-22-2
- $1.00
- 98%
- Career Henan Chemical Co
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