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Cibenzoline succinate

Cibenzoline succinate Structure
Cibenzoline succinate structure
CAS No.
100678-32-8
Chemical Name:
Cibenzoline succinate
Synonyms
ritmalan;ole(1:1);cipralan;Cinobezile;ro22-7796/001;Cibenzoline succinate;cibenzolinesuccinate(1:1);(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1);4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate;4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate
CBNumber:
CB7255168
Molecular Formula:
C18H18N2.C4H6O4
Molecular Weight:
380.44
MDL Number:
MFCD00941423
MOL File:
100678-32-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:59:59
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Cibenzoline succinate Properties

Melting point 165°
storage temp. 2-8°C
solubility H2O: ≥5mg/mL
form solid
color white to off-white
Water Solubility H2O: ≥5mg/mL
Stability Light Sensitive
InChI 1S/C18H18N2.C4H6O4/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17;5-3(6)1-2-4(7)8/h1-10,16H,11-13H2,(H,19,20);1-2H2,(H,5,6)(H,7,8)
InChIKey XFUIOIWYMHEPIE-UHFFFAOYSA-N
SMILES OC(=O)CCC(O)=O.C1CN=C(N1)C2CC2(c3ccccc3)c4ccccc4
FDA UNII 38G16RWJ37
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  EJ9960100
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

Cibenzoline succinate price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C1618 Cibenzoline succinate ≥97% (NMR), solid 100678-32-8 10mg $212 2026-04-30 Buy
Sigma-Aldrich C1618 Cibenzoline succinate ≥97% (NMR), solid 100678-32-8 50mg $634 2026-04-30 Buy
aablocks AA0002JB Cibenzolinesuccinate 98% 100678-32-8 100mg $675 2026-05-25 Buy
aablocks AA0002JB Cibenzolinesuccinate 98% 100678-32-8 1g $2550 2026-05-25 Buy
TRC C535725 Cibenzoline succinate 100678-32-8 5mg $115 2021-12-16 Buy
Product number Packaging Price Buy
C1618 10mg $212 Buy
C1618 50mg $634 Buy
AA0002JB 100mg $675 Buy
AA0002JB 1g $2550 Buy
C535725 5mg $115 Buy

Cibenzoline succinate Chemical Properties,Uses,Production

Uses

Cardiac depressant (anti-arrhythmic).

Uses

Cibenzoline Succinate acts as a highly active class I antiarrhythmic agent.

Definition

ChEBI: Cibenzoline succinate is a diarylmethane.

General Description

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S() forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

Biochem/physiol Actions

Cibenzoline is a class IA antiarrhythmic drug. Cibenzoline (μM concentrations) blocks ATP-sensitive K channels in heart and pancreatic cells. Cibenzoline interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Cibenzoline also inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.

Cibenzoline succinate Preparation Products And Raw materials

Raw materials

Preparation Products

Cibenzoline succinate Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
LGC Science (Shanghai) Ltd. 17717235263 17717235263 offer.de@lgcgroup.com China 38135 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 info@chemextension.com China 42052 58
Supplier Advantage
Sigma-Aldrich 80
Aikon International Limited 58
Career Henan Chemica Co 58
CONIER CHEM AND PHARMA LIMITED 58
Energy Chemical 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol 58
LGC Science (Shanghai) Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

100678-32-8(Cibenzoline succinate)Related Search:

Cefazolin Methylprednisolone sodium succinate Cefazolin sodium salt Tolazoline hydrochloride Dichlorodiphenylsilane
Metroprolol succinate Succinic acid iron succinate 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Disodium succinate
Chlorodiphenylphosphine Imidazole Dioctyl sulfosuccinate sodium salt Oxymetazoline hydrochloride BUTYRAMIDINE
Cibenzoline Cibenzoline succinate 4-methylpentanimidamide

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(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1) ole(1:1) ritmalan ro22-7796/001 succinic acid, compound with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2) 2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate, Cibenol, Cipralan, Exacor Cinobezile Cibenzoline succinate 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazol(+-)-1h-imidazolbutanedioate( 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate 4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazole(1:1) cibenzolinesuccinate(1:1) cipralan 100678-32-8 C18H18N2C4H6O4 Cell Biology Cell Signaling and Neuroscience BioChemical Voltage-gated Ion Channels Potassium Channel Modulators Ion Channels Monovalent Ion Channels Heterocyclic Compounds