ChemicalBook >> CAS DataBase List >>9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene structure

CAS No.: 1389439-77-3

Chemical Name:: 9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene

Synonyms: TY-011;9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene;5-(2-chlorophenyl)-8-ethyl-3-methyl-2,10-dihydropyrazolo[3,4-b]pyrido[4,3-e][1,4]diazepine;Pyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepine, 5-(2-chlorophenyl)-8-ethyl-1,2-dihydro-3-methyl-

CBNumber:: CB72582633

Molecular Formula:: C18H16ClN5

Molecular Weight:: 337.81

MDL Number:: MFCD19707648

MOL File:: 1389439-77-3.mol

Last updated:2026-05-28 04:46:27

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9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Properties

Boiling point	541.8±50.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Store at 0-8 °C
pka	16.46±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ACHEMBLOCK	C-2945	9-(2-Chloro-phenyl)-6-ethyl-1-methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene 98%	1389439-77-3	1G	$3950	2026-05-27	Buy

Product number	Packaging	Price	Buy
C-2945	1G	$3950	Buy

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Chemical Properties, Uses, Production

Uses

TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis (Apoptosis) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC50 value ranging from 0.11 to 4.49 μM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research[1].

IC 50

Aurora A; Aurora B

References

[1] Jiang T, et al. Antitumor activity of a novel Aurora A/B kinases inhibitor TY-011 against gastric cancer by inducing DNA damage. Anticancer Drugs. 2020 Jun;31(5):440-451. DOI:10.1097/CAD.0000000000000928

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Preparation Products And Raw materials

Raw materials

Preparation Products

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Suppliers

Global Suppliers ( 2)

Supplier	Tel	Email	Country	ProdList	Advantage
EnliPharma Technology Co., Ltd	0551-66399836 18955197623	sales@enlipharma.com	China	1875	55
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
EnliPharma Technology Co., Ltd	55
TargetMol Chemicals Inc.	58

1389439-77-3 (9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene) Related Search:

9-(2-Chloro-phenyl)-1,6-diMethyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene 9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Ethyl 8-methoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate AT9283 PF 477736

PF-03814735

1of2

9-(2-Chloro-phenyl)-6-ethyl-1-Methyl-2,4-dihydro-2,3,4,7,10-pentaaza-benzo[f]azulene Pyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepine, 5-(2-chlorophenyl)-8-ethyl-1,2-dihydro-3-methyl- TY-011 5-(2-chlorophenyl)-8-ethyl-3-methyl-2,10-dihydropyrazolo[3,4-b]pyrido[4,3-e][1,4]diazepine 1389439-77-3