Tetrahydro-pyran-3-carbaldehyde
- CAS No.
- 77342-93-9
- Chemical Name:
- Tetrahydro-pyran-3-carbaldehyde
- Synonyms
- tetrahydro-2H-pyran-3-carbaldehyde;RARECHEM AK ML 0583;oxane-3-carbaldehyde;tetrahydro-2h-pyran-3-carbaL;3-Tetrahydropyrancarbaldehyde;Tetrahydro-pyran-3-carbaldehyde;tetrahydropyran-3-carboxaldehyde;Tetrahydro-2H-pyran-3-carboxaldehyde;2H-PYRAN-3-CARBOXALDEHYDE, TETRAHYDRO-;2H-Pyran-3-carboxaldehyde, tetrahydro- (9CI)
- CBNumber:
- CB7290655
- Molecular Formula:
- C6H10O2
- Molecular Weight:
- 114.14
- MDL Number:
- MFCD03789633
- MOL File:
- 77342-93-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| HS Code | 2932990090 |
Tetrahydro-pyran-3-carbaldehyde price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR70049 | Tetrahydro-2H-pyran-3-carboxaldehyde 90% | 77342-93-9 | 250mg | $52 | 2026-06-04 | Buy |
| Apolloscientific | OR70049 | Tetrahydro-2H-pyran-3-carboxaldehyde 90% | 77342-93-9 | 1g | $94 | 2026-06-04 | Buy |
| Apolloscientific | OR70049 | Tetrahydro-2H-pyran-3-carboxaldehyde 90% | 77342-93-9 | 2.5g | $210 | 2026-06-04 | Buy |
| Chem-Impex | 18226 | Tetrahydropyran-3-carbaldehyde ≥99%(NMR) | 77342-93-9 | 250MG | $95 | 2026-05-19 | Buy |
| Chem-Impex | 18226 | Tetrahydropyran-3-carbaldehyde ≥99%(NMR) | 77342-93-9 | 1G | $190 | 2026-05-19 | Buy |
Tetrahydro-pyran-3-carbaldehyde Chemical Properties, Uses, Production
Uses
Tetrahydro-pyran-3-carbaldehyde is a key intermediate for the synthesis of a novel 5-lipoxygenase inhibitor. Also it is a reactant used to synthesize tetrahydropyran esters as attractant toward Blattella germanica and Supella longipalpa.
Synthesis
13417-49-7
77342-93-9
General procedure for the synthesis of tetrahydropyran-3-carbaldehyde from 5,6-dihydro-2H-pyran-3-carbaldehyde: 10% Pd/C catalyst (600 mg) was slowly added to a solution of 5,6-dihydro-2H-pyran-3-carbaldehyde (6 g, 53.5 mmol) in methanol (10 mL). The reaction mixture was stirred under hydrogen (40 psi) atmosphere. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth, the precipitate was washed with methanol and the filtrate was concentrated under vacuum. The residue was purified by fractional distillation at 125°C/20 mmHg to afford tetrahydropyran-3-carbaldehyde (5.5 g, 91.6% yield). Mass spectral (MS) data (m/z): [M + H]+, 115.1.
References
[1] Molecular Pharmacology, 2015, vol. 87, # 3, p. 477 - 491
[2] Patent: WO2016/85939, 2016, A2. Location in patent: Paragraph 00260
[3] Patent: US5071863, 1991, A
[4] Chemistry and Industry (London, United Kingdom), 1955, p. 1772
Tetrahydro-pyran-3-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Aemon Chemical | 0086-755-86198205 | acinfo@aemonchem.com | China | 1928 | 57 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Ascepion Pharmaceuticals, Inc. | +86-512-86881668 | China | 100 | 58 |
77342-93-9 (Tetrahydro-pyran-3-carbaldehyde) Related Search:
1of4
