2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid
- CAS No.
- 365542-77-4
- Chemical Name:
- 2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid
- Synonyms
- Sm4,Sm-4;2-Hydroxy-6-[2-(2-naphthyl)ethyl]benzoic acid;2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid;Benzoic acid, 2-hydroxy-6-[2-(2-naphthalenyl)ethyl]-;2-Hydroxy-6-(2-(naphthalen-2-yl)ethyl)benzoic acid , Sm4
- CBNumber:
- CB73038650
- Molecular Formula:
- C19H16O3
- Molecular Weight:
- 292.33
- MDL Number:
- MFCD12546734
- MOL File:
- 365542-77-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | 2-8°C |
|---|---|
| solubility | DMSO: 2mg/mL, clear |
| form | Solid |
| color | Off-white to light brown |
| InChI | 1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22) |
| InChIKey | GGVFBUYNEPBFQT-UHFFFAOYSA-N |
| SMILES | OC1=C(C(O)=O)C(CCC2=CC3=C(C=CC=C3)C=C2)=CC=C1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1999 | Sm4 ≥98% (HPLC) | 365542-77-4 | 5MG | $163 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1999 | Sm4 ≥98% (HPLC) | 365542-77-4 | 25MG | $655 | 2026-04-30 | Buy |
| ChemScene | CS-0066852 | Sm4 99.01% | 365542-77-4 | 5mg | $206 | 2026-06-04 | Buy |
| ChemScene | CS-0066852 | Sm4 99.01% | 365542-77-4 | 10mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0066852 | Sm4 99.01% | 365542-77-4 | 25mg | $650 | 2026-06-04 | Buy |
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Chemical Properties, Uses, Production
Description
Sm4 is a novel SOX18 blocker, suppressing genes downstream of the gene for Sox18 and interferring with vascular development, showing anti-cancer and anti-metastatic effects.
Uses
Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].
References
[1] Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1.
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Hydroxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9970 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Shanghai shuji biotechnology co., ltd. | 021-021-62200788 15000569291 | zhanlingrui@163.com | China | 500 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2934 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
