(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid
- CAS No.
- 582314-48-5
- Chemical Name:
- (1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid
- Synonyms
- CAY10443;CKERQCMQSBFFKX-INIZCTEOSA-N;(S)-INDAN-1-YL 3,4-DICHLOROBENZYLCARBAMATE;(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid;Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1S)-2,3-dihydro-1H-inden-1-yl ester (9CI)
- CBNumber:
- CB7308552
- Molecular Formula:
- C17H15Cl2NO2
- Molecular Weight:
- 336.21
- MDL Number:
- MFCD08062128
- MOL File:
- Mol file
- MSDS File:
- SDS
| Boiling point | 495.6±45.0 °C(Predicted) |
|---|---|
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 11.15±0.46(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10004177 | CAY10443 ≥98% | 582314-48-5 | 5mg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 10004177 | CAY10443 ≥98% | 582314-48-5 | 10mg | $102 | 2026-04-30 | Buy |
| Cayman Chemical | 10004177 | CAY10443 ≥98% | 582314-48-5 | 25mg | $238 | 2026-04-30 | Buy |
| Cayman Chemical | 10004177 | CAY10443 ≥98% | 582314-48-5 | 50mg | $424 | 2026-04-30 | Buy |
| ChemScene | CS-0066288 | Apoptosis inducer 34 98% | 582314-48-5 | 5mg | $157 | 2026-06-04 | Buy |
(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Chemical Properties, Uses, Production
Uses
Apoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].
Definition
ChEBI: Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1s)-2,3-dihydro-1h-inden-1-yl ester is a member of indanes.
References
[1] Nguyen JT, et al. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8. DOI:10.1073/pnas.1031631100
(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7982 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |






