ChemicalBook >> CAS DataBase List >>Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester structure

CAS No.: 65974-52-9

Chemical Name:: Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester

Synonyms: NCI126224;Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester

CBNumber:: CB73255587

Molecular Formula:: C12H11NO6

Molecular Weight:: 265.21884

MDL Number:

MOL File:: 65974-52-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:11

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Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester Properties

solubility	Chloroform: Soluble Methanol: Soluble
form	Solid
color	White to off-white

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	39520	NCI 126224 ≥98%	65974-52-9	1mg	$28	2026-04-30	Buy
Cayman Chemical	39520	NCI 126224 ≥98%	65974-52-9	5mg	$104	2026-04-30	Buy
Cayman Chemical	39520	NCI 126224 ≥98%	65974-52-9	10mg	$165	2026-04-30	Buy
Cayman Chemical	39520	NCI 126224 ≥98%	65974-52-9	25mg	$310	2026-04-30	Buy
ChemScene	CS-0891816	NCI126224 99.88%	65974-52-9	5mg	$103	2026-06-04	Buy

Product number	Packaging	Price	Buy
39520	1mg	$28	Buy
39520	5mg	$104	Buy
39520	10mg	$165	Buy
39520	25mg	$310	Buy
CS-0891816	5mg	$103	Buy

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester Chemical Properties, Uses, Production

Uses

NCI126224 is a TLR4 signaling inhibitor. NCI126224 suppress LPS (HY-D1056)-induced production of NF-κB, TNF-α, IL-1β, and NO in the nanomolar-low micromolar range. NCI126224 can be used for the research of inflammatory diseases[1].

References

[1] Zhang S, et, al. Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors. Bioorg Med Chem. 2012 Oct 15;20(20):6073-9. DOI:10.1016/j.bmc.2012.08.022

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester Suppliers

Global Suppliers ( 8)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2934	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5985	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58
Zhejiang Huida Biotech Co., Ltd.	0571-89903022 18679456698	zilong@hizyme.com	China	7853	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai Tachizaki Biomedical Research Center	58
Nantong QuanYi Biotechnology Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Zhejiang Huida Biotech Co., Ltd.	58

65974-52-9 (Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester) Related Search:

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Propanedioic acid,2-[(2-nitrophenyl)methylene]-, 1,3-dimethyl ester NCI126224 65974-52-9