ChemicalBook >> CAS DataBase List >>Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
- CAS No.
- 174072-89-0
- Chemical Name:
- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
- Synonyms
- RELU-001;Relugolix Intermediate 6;2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic a;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOX...;ethyl 2-amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylate;Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylat;2-Amino-4-methyl-5-(4-nitrobenzene Ethyl thiophene-3-carboxylate;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE;2-Amino-4-methyl-5- (4-nitrophenyl) -3-thiophene carboxylate ethyl ester;2-amino-4-methyl-5-(4-nitrophenyl)-thiophen-3-carboxylic acid ethyl ester
- CBNumber:
- CB7325744
- Molecular Formula:
- C14H14N2O4S
- Molecular Weight:
- 306.34
- MDL Number:
- MFCD04115279
- MOL File:
- 174072-89-0.mol
- MSDS File:
- SDS
Last updated:2025-07-16 09:53:41
| Product description | Number | Pack Size | Price |
| Ethyl2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate | 6682AH | 250mg | $208 |
| Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | CS-0099673 | 1g | $279 |
| Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | CS-0099673 | 250mg | $181 |
| ETHYL-2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE 97.00% | CHM0151855 | 5MG | $498.4 |
| Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | CS-0099673 | 5g | $701 |
| More product size | |||
| Boiling point | 464.6±45.0 °C(Predicted) |
|---|---|
| Density | 1.337 |
| Flash point | 234.78oC |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -0.68±0.10(Predicted) |
| Appearance | Pink to red Solid |
| InChI | InChI=1S/C14H14N2O4S/c1-3-20-14(17)11-8(2)12(21-13(11)15)9-4-6-10(7-5-9)16(18)19/h4-7H,3,15H2,1-2H3 |
| InChIKey | CXRJNUVDWUINBY-UHFFFAOYSA-N |
| SMILES | C1(N)SC(C2=CC=C([N+]([O-])=O)C=C2)=C(C)C=1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H351-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501 |
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 6682AH | Ethyl2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate | 174072-89-0 | 250mg | $208 | 2021-12-16 | Buy |
| ChemScene | CS-0099673 | Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | 174072-89-0 | 1g | $279 | 2021-12-16 | Buy |
| ChemScene | CS-0099673 | Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | 174072-89-0 | 250mg | $181 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0151855 | ETHYL-2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE 97.00% | 174072-89-0 | 5MG | $498.4 | 2021-12-16 | Buy |
| ChemScene | CS-0099673 | Ethyl2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate | 174072-89-0 | 5g | $701 | 2021-12-16 | Buy |
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Chemical Properties,Uses,Production
Uses
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate is an intermediate compound used in the synthesis of Relugolix, which belongs to a class of gonadotropin-releasing hormone (GnRH) receptor antagonists used to treat advanced prostate cancer in adult men. Relugolix belongs to a group of Gonadotropin-releasing hormone (GnRH) receptor antagonists that are used to treat advanced prostate cancer in adult men.



Synthesis of Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate from 4-NITROPHENYLACETONE and Ethyl cyanoacetate
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Preparation Products And Raw materials
Global( 138)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Suzhou Nordica Biopharma CO.,LTD | +86-18136148818 +86-18567353071 | 3537297702@qq.com | China | 299 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8792 | 58 |
View Lastest Price from Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate
174072-89-0
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
![]() |
2025-09-25 | Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
![]() |
2025-05-07 | Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
|
US $0.00-0.00 / kg | 1kg | 99% by HPLC | 20 tons | Suzhou Nordica Biopharma CO.,LTD |
-

- Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate
174072-89-0
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-

- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
- US $0.00-0.00 / kg
- 99% by HPLC
- Suzhou Nordica Biopharma CO.,LTD
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174072-89-0






