ChemicalBook >> CAS DataBase List >>Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
- CAS No.
- 174072-89-0
- Chemical Name:
- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
- Synonyms
- RELU-001;Relugolix Intermediate 6;2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic a;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOX...;ethyl 2-amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylate;Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylat;2-Amino-4-methyl-5-(4-nitrobenzene Ethyl thiophene-3-carboxylate;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE;2-Amino-4-methyl-5- (4-nitrophenyl) -3-thiophene carboxylate ethyl ester;2-amino-4-methyl-5-(4-nitrophenyl)-thiophen-3-carboxylic acid ethyl ester
- CBNumber:
- CB7325744
- Molecular Formula:
- C14H14N2O4S
- Molecular Weight:
- 306.34
- MDL Number:
- MFCD04115279
- MOL File:
- 174072-89-0.mol
- MSDS File:
- SDS
Last updated:2026-05-28 04:45:08
| Boiling point | 464.6±45.0 °C(Predicted) |
|---|---|
| Density | 1.337 |
| Flash point | 234.78oC |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -0.68±0.10(Predicted) |
| Appearance | Pink to red Solid |
| InChI | InChI=1S/C14H14N2O4S/c1-3-20-14(17)11-8(2)12(21-13(11)15)9-4-6-10(7-5-9)16(18)19/h4-7H,3,15H2,1-2H3 |
| InChIKey | CXRJNUVDWUINBY-UHFFFAOYSA-N |
| SMILES | C1(N)SC(C2=CC=C([N+]([O-])=O)C=C2)=C(C)C=1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H351-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501 |
| REACH Registrations | Active |
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FE56713 | Ethyl-2-amino-4-methyl-5-(4-nitrophenyl)-thiophene-3-carboxylate | 174072-89-0 | 50g | $900 | 2026-06-04 | Buy |
| Biosynth | FE56713 | Ethyl-2-amino-4-methyl-5-(4-nitrophenyl)-thiophene-3-carboxylate | 174072-89-0 | 500g | $900 | 2026-06-04 | Buy |
| Biosynth | FE56713 | Ethyl-2-amino-4-methyl-5-(4-nitrophenyl)-thiophene-3-carboxylate | 174072-89-0 | 25g | $900 | 2026-06-04 | Buy |
| Biosynth | FE56713 | Ethyl-2-amino-4-methyl-5-(4-nitrophenyl)-thiophene-3-carboxylate | 174072-89-0 | 250g | $900 | 2026-06-04 | Buy |
| Biosynth | FE56713 | Ethyl-2-amino-4-methyl-5-(4-nitrophenyl)-thiophene-3-carboxylate | 174072-89-0 | 100g | $900 | 2026-06-04 | Buy |
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Chemical Properties, Uses, Production
Uses
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate is an intermediate compound used in the synthesis of Relugolix, which belongs to a class of gonadotropin-releasing hormone (GnRH) receptor antagonists used to treat advanced prostate cancer in adult men. Relugolix belongs to a group of Gonadotropin-releasing hormone (GnRH) receptor antagonists that are used to treat advanced prostate cancer in adult men.
Synthesis of Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate from 4-Nitrophenylacetone and Ethyl cyanoacetate
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Preparation Products And Raw materials
Global Suppliers ( 143)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Chemtrue Bio-Tech Co.,Ltd. | 19967494293 | sales@chemtrue-bio.com | China | 303 | 58 |
| Suzhou Sino Rare Chemical Co., Ltd. | 0512-62857507 | sales@sinorarechem.com | China | 999 | 58 |
| Jiangsu Vcare PharmaTech Co., Ltd. | 025-58741518 13327700685 | sales@vcarepharmatech.com | China | 281 | 61 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7601 | 58 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 28-83379370 13880556291 | tcy@tcypharm.com | China | 509 | 57 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Atop-Pharma (Shanghai) Technology Co., Ltd. | +86 (21) 5196-9732 | China | 996 | 57 | |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai SE Pharm Co., Ltd | 18112588827 | sales4@sepharm.com.cn | China | 285 | 60 |
View Latest Price from Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate
174072-89-0
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-05-07 | Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
|
1kg | 99% by HPLC | 20 tons | Suzhou Nordica Biopharma CO.,LTD |
-
- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate
174072-89-0
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
174072-89-0
- 99% by HPLC
- Suzhou Nordica Biopharma CO.,LTD
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ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE
2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylic acid ethyl ester
2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic acid ethyl ester
Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylat
RELU-001
2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic a
3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-(4-nitrophenyl)-, ethyl ester
2-amino-4-methyl-5-(4-nitrophenyl)-thiophen-3-carboxylic acid ethyl ester
ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH
ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOX...
Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylateQ: What is
Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate Q: What is the CAS Number of
Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate
Relugolix Intermediate 6
2-Amino-4-methyl-5-(4-nitrobenzene
Ethyl thiophene-3-carboxylate
2-Amino-4-methyl-5- (4-nitro-phenyl)-thiophene-3- carboxylic acid ethyl estei
Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylate (API Intermediate)
2-Amino-4-methyl-5- (4-nitrophenyl) -3-thiophene carboxylate ethyl ester
ethyl 2-amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylate
174072-89-0
