PURPUROGALLIN
- CAS No.
- 569-77-7
- Chemical Name:
- PURPUROGALLIN
- Synonyms
- C09964;MLS0007;NSC 35676;NSC 646653;AIDS138915;CHEBI:8647;AIDS-138915;AKOS 209-004;KBio1_001351;KBio2_000828
- CBNumber:
- CB7329636
- Molecular Formula:
- C11H8O5
- Molecular Weight:
- 220.18
- MDL Number:
- MFCD00004145
- MOL File:
- 569-77-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Purpurogallin ≥95% | 29689 | 50mg | $42 |
| Purpurogallin ≥95% | 29689 | 100mg | $74 |
| Purpurogallin ≥95% | 29689 | 500mg | $183 |
| Purpurogallin ≥95% | 29689 | 1g | $322 |
| 2,3,4,6-Tetrahydroxy-5H-benzo[7]annulen-5-one | TRC-B416273-50MG | 50mg | $64 |
| Melting point | 275 °C (dec.)(lit.) |
|---|---|
| Boiling point | 321.11°C (rough estimate) |
| Density | 1.3824 (rough estimate) |
| refractive index | 1.5140 (estimate) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.75±0.20(Predicted) |
| form | Solid |
| color | Very Dark Brown |
| Merck | 7946 |
| Stability | Air Sensitive |
| Cosmetics Ingredients Functions |
HUMECTANT SKIN CONDITIONING |
| LogP | 2.050 (est) |
| FDA UNII | L3Z7U4N28P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DE8380000 | |||||||||
| NFPA 704 |
|
PURPUROGALLIN price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29689 | Purpurogallin ≥95% | 569-77-7 | 50mg | $42 | 2026-04-30 | Buy |
| Cayman Chemical | 29689 | Purpurogallin ≥95% | 569-77-7 | 100mg | $74 | 2026-04-30 | Buy |
| Cayman Chemical | 29689 | Purpurogallin ≥95% | 569-77-7 | 500mg | $183 | 2026-04-30 | Buy |
| Cayman Chemical | 29689 | Purpurogallin ≥95% | 569-77-7 | 1g | $322 | 2026-04-30 | Buy |
| TRC | TRC-B416273-50MG | 2,3,4,6-Tetrahydroxy-5H-benzo[7]annulen-5-one | 569-77-7 | 50mg | $64 | 2026-06-03 | Buy |
PURPUROGALLIN Chemical Properties,Uses,Production
Description
Purpurogallin is a phenol that has been found in D. divisa and a derivative of pyrogallol that has diverse biological activities, including antimicrobial, antioxidant, and enzyme inhibitory properties. It is active against the Gram-positive bacteria S. aureus, methicillin-resistant S. aureus (MRSA), S. epidermidis, and B. subtilis (MICs = 11-110 μg/ml), the Gram-negative bacteria S. marcescens, P. vulgaris, K. pneumoniae, E. coli, S. typhi, and E. cloacae (MIC = 110 μg/ml for all), as well as P. falciparum strain FCB1 clone NC-1 (IC50 = 55 μM). Purpurogallin (2, 5, and 10 μM) scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay and reduces hydrogen peroxide- and radiation-induced production of reactive oxygen species (ROS) in HaCaT keratinocytes. It inhibits the activity of EGFR, glutathione-S-transferase (GST), prolyl endopeptidase, and glyoxalase I (IC50s = 27.5, 8, 16, and 50 μM, respectively), as well as catechol O-methyltransferase (COMT; Ki = 0.074 μM), in cell-free assays.
Chemical Properties
BROWN FINE CRYSTALLINE POWDER
Uses
xanthine oxidase inhibitor, antioxidant
Definition
ChEBI: A cyclic ketone that is 5H-benzocycloheptene bearing an oxo group at position 5 and hydroxy groups at positions 2, 3, 4 and 6.
Enzyme inhibitor
This aglycone (FW = 220.18 g/mol) of a number of glycosides (e.g., dryophantin) from several nutgalls. Purpurogallin is a scavenger of polymorphonuclear leukocyte-derived oxyradicals and acts as a cardioprotector. Target(s): catechol O-methyltransferase; cystathionine b-synthase; glutathione-disulfide reductase; glutathione S-transferase; HIV-1 integrase; lactoylglutathione lyase, or glyoxalase I; 3-phosphoglycerate kinase; prolyl endopeptidase; protein-tyrosine kinase; and xanthine oxidase.
References
[1] Y INAMORI. Biological activity of purpurogallin.[J]. Bioscience, Biotechnology, and Biochemistry, 1997, 61 5: 890-892. DOI: 10.1271/bbb.61.890
[2] AO XUAN ZHEN. Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5.[J]. Biomolecules & Therapeutics, 2019, 27 4: 395-403. DOI: 10.4062/biomolther.2018.151
[3] JOHN F. BARNARD John F H David L Vander Jagt. Small molecule probes of glyoxalase I and glyoxalase II[J]. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994, 1208 1: Pages 127-135. DOI: 10.1016/0167-4838(94)90169-4
[4] M ABOU-KARAM W T S. Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by purpurogallin from Quercus sp. nutgall.[J]. Phytotherapy Research, 1999, 13 4: 337-340. DOI: 10.1002/(sici)1099-1573(199906)13:4<337::aid-ptr451>3.0.co;2-j
[5] MUKUL DAS Hasan M David R Bickers. Plant phenols as invitro inhibitors of glutathione S-transferase(s)[J]. Biochemical and biophysical research communications, 1984, 120 2: Pages 427-433. DOI: 10.1016/0006-291x(84)91271-3
[6] VESER J. Kinetics and inhibition studies of catechol O-methyltransferase from the yeast Candida tropicalis.[J]. Journal of Bacteriology, 1987, 169 8: 3696-3700. DOI: 10.1128/jb.169.8.3696-3700.1987
PURPUROGALLIN Preparation Products And Raw materials
Raw materials
Preparation Products
PURPUROGALLIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49860 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44848 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 | info@chemlin.com.cn | China | 16305 | 64 |
View Lastest Price from PURPUROGALLIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Purpurogallin
569-77-7
|
$48.00-123.00 | 98.89% | 10g | TargetMol Chemicals Inc. |
-
- Purpurogallin
569-77-7
- $48.00-123.00
- 98.89%
- TargetMol Chemicals Inc.
