2,4-Dihydroxyacetophenone
- CAS No.
- 89-84-9
- Chemical Name:
- 2,4-Dihydroxyacetophenone
- Synonyms
- 1-(2,4-dihydroxyphenyl)ethanone;RESACETOPHENONE;Ethanone, 1-(2,4-dihydroxyphenyl)-;2',4'-Dihydroxyacetophenone;2,4-DHAP;4-ACETYLRESORCINOL;HyMechroMone;NSC 37559;NSC 10883;AKOS 90593
- CBNumber:
- CB4391766
- Molecular Formula:
- C8H8O3
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD00002279
- MOL File:
- 89-84-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 143-144.5 °C(lit.) |
|---|---|
| Boiling point | 234.6°C (rough estimate) |
| Density | 1.18 g/mL at 25 °C(lit.) |
| refractive index | 1.4945 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 7.96±0.18(Predicted) |
| form | Crystalline Powder or Crystals |
| color | Off-white to pink to brown |
| PH | 5 (1g/l, H2O, 20℃) |
| Sensitive | Moisture Sensitive |
| Merck | 14,8140 |
| BRN | 1282505 |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING BLEACHING ANTIOXIDANT |
| InChI | 1S/C8H8O3/c1-5(9)7-3-2-6(10)4-8(7)11/h2-4,10-11H,1H3 |
| InChIKey | SULYEHHGGXARJS-UHFFFAOYSA-N |
| SMILES | CC(=O)c1ccc(O)cc1O |
| LogP | 1.480 (est) |
| CAS DataBase Reference | 89-84-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | UC3V356VZC |
| NIST Chemistry Reference | Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9) |
| EPA Substance Registry System | Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AM7525000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29145000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2,4-Dihydroxyacetophenone price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D107409 | 2′,4′-Dihydroxyacetophenone 99% | 89-84-9 | 100g | $103 | 2026-04-30 | Buy |
| Sigma-Aldrich | D107409 | 2′,4′-Dihydroxyacetophenone 99% | 89-84-9 | 500g | $303 | 2026-04-30 | Buy |
| TCI Chemical | D0561 | 2',4'-Dihydroxyacetophenone >98.0%(GC)(T) | 89-84-9 | 25g | $40 | 2026-04-30 | Buy |
| TCI Chemical | D0561 | 2',4'-Dihydroxyacetophenone >98.0%(GC)(T) | 89-84-9 | 100g | $102 | 2026-04-30 | Buy |
| TRC | TRC-D450085-5G | 2',4'-Dihydroxyacetophenone | 89-84-9 | 5g | $63 | 2026-06-03 | Buy |
2,4-Dihydroxyacetophenone Chemical Properties, Uses, Production
Chemical Properties
2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.
Uses
2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).
Definition
ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.
Preparation
Preparation by reaction of acetic acid on resorcinol,
with zinc chloride (Nencki reaction) (94%)
with boron trifluoride
with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%)
with polyphosphoric acid (63%)
with 70% perchloric acid (33%).
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 428, 1948 DOI: 10.1021/ja01181a521
Safety Profile
Moderately toxic by ingestion. Experimental reproductive effects. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Synthesis
2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.
target
Phospholipase (e.g. PLA)
2,4-Dihydroxyacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Xinshuo New Material Technology Co., Ltd. | 18257124775,15967699685 15967699685; | 3762199508@qq.com | China | 29 | 58 |
| Shanghai F.R. Chemical Technology Co.,Ltd | 021-52230662 13795399395 | seaman79@126.com | China | 295 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from 2,4-Dihydroxyacetophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | 2,4-Dihydroxyacetophenone
89-84-9
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-18 | 2,4-Dihydroxyacetophenone
89-84-9
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-06-30 | 2,4-Dihydroxyacetophenone
89-84-9
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 2,4-Dihydroxyacetophenone
89-84-9
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2,4-Dihydroxyacetophenone
89-84-9
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 2,4-Dihydroxyacetophenone
89-84-9
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
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