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N-(Amino-PEG4)-N-Biotin-PEG4-acid

CAS No.
2100306-84-9
Chemical Name:
N-(Amino-PEG4)-N-Biotin-PEG4-acid
Synonyms
N-(Amino-PEG4)-N-Biotin-PEG4-acid;4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 16-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-21-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, rel-
CBNumber:
CB73373674
Molecular Formula:
C31H58N4O12S
Molecular Weight:
710.88
MDL Number:
MFCD31692208
MOL File:
2100306-84-9.mol
Last updated:2026-07-28 20:33:13

N-(Amino-PEG4)-N-Biotin-PEG4-acid Properties

Boiling point 861.058±65.00 °C(Press: 760.00 Torr)(predicted)
Density 1.188±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility Soluble in Water, DMSO, DMF
pka 4.275±0.10(predicted)

N-(Amino-PEG4)-N-Biotin-PEG4-acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114727 N-(Amino-PEG4)-N-Biotin-PEG4-acid ≥98% 2100306-84-9 1g $1845 2026-06-04 Buy
BroadPharm bp-23650 N-(Amino-PEG4)-N-Biotin-PEG4-acid 98% 2100306-84-9 100MG $380 2026-05-24 Buy
BroadPharm bp-23650 N-(Amino-PEG4)-N-Biotin-PEG4-acid 98% 2100306-84-9 250MG $750 2026-05-24 Buy
BroadPharm bp-23650 N-(Amino-PEG4)-N-Biotin-PEG4-acid 98% 2100306-84-9 500MG $1200 2026-05-24 Buy
aablocks AA019EB4 N-(Amino-PEG4)-N-Biotin-PEG4-acid >96% 2100306-84-9 100mg $445 2026-05-29 Buy
Product number Packaging Price Buy
CS-0114727 1g $1845 Buy
bp-23650 100MG $380 Buy
bp-23650 250MG $750 Buy
bp-23650 500MG $1200 Buy
AA019EB4 100mg $445 Buy

N-(Amino-PEG4)-N-Biotin-PEG4-acid Chemical Properties, Uses, Production

Description

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a 3-arm biotinylation reagent with terminal amine(NH2) and carboxylic acid moieties. The amine group can react with activated NHS esters. Carboxylic acid can conjugate with primary amines in the presence of activators such as EDC or HATU to form stable amide bonds.

Uses

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

N-(Amino-PEG4)-N-Biotin-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Amino-PEG4)-N-Biotin-PEG4-acid Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38923 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Shanghai Yanfen Biochemical Technology Co.,LTD 17721070236 yanfen2026@126.com China 2198 58
Affinity Linkers Ltd. 15841022315 15841022315 sales@affinitytech.cn China 7039 58

View Latest Price from N-(Amino-PEG4)-N-Biotin-PEG4-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(Amino-PEG4)-N-Biotin-PEG4-acid pictures 2025-06-07 N-(Amino-PEG4)-N-Biotin-PEG4-acid
2100306-84-9
500mg >95.00% 500mg Xian confluore Biological Technology Co., Ltd.
N-(Amino-PEG4)-N-Biotin-PEG4-acid 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 16-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-21-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, rel- 2100306-84-9 C31H58N4O12S