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1-Boc-4-(aminomethyl)piperidine

1-Boc-4-(aminomethyl)piperidine structure

CAS No.: 144222-22-0

Chemical Name:: 1-Boc-4-(aminomethyl)piperidine

Synonyms: BOC-4-(AMINOMETHYL)-PIPERIDINE;1-N-Boc-4-(aminomethyl)piperidine;4-(aminometh;BOC-PIP(4-AM);CAS:144222-22-0;BUTTPARK 90\06-09;)piperidine-1-carboxyL;1-Boc-4-aminomethylpiperi...;1-Boc-4-aMinoMethylpiperdine;1-BOC-4-PIPERIDYLMETHYLAMINE

CBNumber:: CB7408465

Molecular Formula:: C11H22N2O2

Molecular Weight:: 214.31

MDL Number:: MFCD01076207

MOL File:: 144222-22-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:06:22

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1-Boc-4-(aminomethyl)piperidine Properties

Boiling point	237-238 °C(lit.)
Density	1.013 g/mL at 25 °C(lit.)
refractive index	n20/D 1.473(lit.)
Flash point	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in chloroform and methanol.
form	Liquid or Low Melting Solid
pka	10.13±0.29(Predicted)
color	Colorless to yellow
InChI	InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3
InChIKey	KLKBCNDBOVRQIJ-UHFFFAOYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCC(CN)CC1
CAS DataBase Reference	144222-22-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H315-H319-H335-H400

Precautionary statements

P261-P273-P305+P351+P338-P280a-P304+P340-P405-P501a

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,C,N

Risk Statements

36/37/38-34-50

Safety Statements

26-36-45-36/37/39-24/25-23-61

RIDADR

UN 3082 9 / PGIII

WGK Germany

10-34

HazardClass

IRRITANT

HS Code

29339900

Storage Class

10 - Combustible liquids

REACH Registrations

Active

NFPA 704

	1
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1-Boc-4-(aminomethyl)piperidine price More Price(87)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	641472	1-Boc-4-(aminomethyl)piperidine 97%	144222-22-0	5g	$87.6	2026-04-30	Buy
Sigma-Aldrich	641472	1-Boc-4-(aminomethyl)piperidine 97%	144222-22-0	25g	$417	2026-04-30	Buy
TCI Chemical	B4445	4-(Aminomethyl)-1-tert-butoxycarbonylpiperidine >98.0%(GC)(T)	144222-22-0	1g	$68	2026-04-30	Buy
TCI Chemical	B4445	4-(Aminomethyl)-1-tert-butoxycarbonylpiperidine >98.0%(GC)(T)	144222-22-0	5g	$172	2026-04-30	Buy
TRC	TRC-B620970-5G	N-Boc-4-(aminomethyl)piperidine	144222-22-0	5g	$117	2026-06-03	Buy

Product number	Packaging	Price	Buy
641472	5g	$87.6	Buy
641472	25g	$417	Buy
B4445	1g	$68	Buy
B4445	5g	$172	Buy
TRC-B620970-5G	5g	$117	Buy

1-Boc-4-(aminomethyl)piperidine Chemical Properties, Uses, Production

Chemical Properties

White Low Melting Solid

Uses

1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.

Uses

1-Boc-4-(aminomethyl)piperidine is used in the preparation biologically active compounds and orally active platelet-activating factor antagonists. It is used as an inhibitor for Kinesin spindle protein. It is an active reactant involved in the enantioselective synthesis of N-alkyl terminal aziridines.Precursor in the preparation of a variety of different protein agonists or antagonists including: Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential, Pim-1 inhibitors, and Aspartic acid protease inhibitors.

Synthesis

1-Boc-4-aminomethylpiperidine is an organic intermediate that can be prepared from tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate in three steps.

1-Boc-4-(aminomethyl)piperidine synthesis

Synthesis of 1-Boc-4-(aminomethyl)piperidine from tert-butyl 4-(azidomethyl)piperidine-1-carboxylate(SALTDATA: FREE)

1-Boc-4-(aminomethyl)piperidine Preparation Products And Raw materials

Raw materials

1,1'-Carbonyldiimidazole 4-Methylmorpholine Ethanol Di-tert-butyl dicarbonate Triethylamine

4-Piperidinemethanol Sodium bisulfate 1,4-Dioxane Tosyl chloride Benzaldehyde

Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Isonipecotic acid Dichloromethane

Methanol Sodium hydroxide Petroleum ether Sodium amide Sodium carbonate

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Preparation Products

1-Boc-4-(aminomethyl)piperidine Suppliers

Global Suppliers ( 337)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Hobor Chemical Co., Ltd	13918007836	sales@hoborchem.com	China	423	60
BTC Pharmaceutical CO. Ltd	+86-15716293042 15716293042	info@btcpharm.com	China	822	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60

Supplier	Advantage
Shanghai Hobor Chemical Co., Ltd	60
BTC Pharmaceutical CO. Ltd	55
J & K SCIENTIFIC LTD.	76
INTATRADE GmbH	66
Alfa Aesar	84
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60
JinYan Chemicals(ShangHai) Co.,Ltd.	60

View Latest Price from 1-Boc-4-(aminomethyl)piperidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-02-26	1-Boc-4-(aminomethyl)piperidine 144222-22-0		1kg	98%		BTC Nantong Pharmaceuticals Technology Co.,Ltd
2021-07-02	1-Boc-4-(aminomethyl)piperidine 144222-22-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	1-Boc-4-(aminomethyl)piperidine 144222-22-0	$1.00	1KG	96%	500kg	Career Henan Chemical Co

1-Boc-4-(aminomethyl)piperidine
144222-22-0
98%
BTC Nantong Pharmaceuticals Technology Co.,Ltd

1-Boc-4-(aminomethyl)piperidine
144222-22-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1-Boc-4-(aminomethyl)piperidine
144222-22-0
$1.00
96%
Career Henan Chemical Co

1-Boc-4-(aminomethyl)piperidine Spectrum

1-Boc-4-(aminomethyl)piperidine(144222-22-0)¹HNMR

144222-22-0 (1-Boc-4-(aminomethyl)piperidine) Related Search:

RESMETHRIN TEMPO 4-(Aminomethyl)piperidine Haloperidol Buprofezin

Cyhalofop-butyl Butyl acetate Diethylene glycol monobutyl ether tert-Butyl peroxyacetate tert-Butyl acetate

2-Butoxyethanol 1-Boc-4-Methylaminopiperidine Butyl acrylate 2,2,6,6-Tetramethyl-4-piperidinol tert-Butanol

Carbonyl sulfide Trimethylphosphine oxide Nickel carbonyl

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1-Boc-4-(aminomethyl)piperidine, 1-Boc-4-piperidylmethylamine 4-(aminometh t-Butyl 4-(aminomethyl)piperidine-1-carboxylate 1-Boc-4-(aminomethyl)piperidine ,97% 4-(Aminomethyl)piperidine, N1-BOC protected 97% 1-Boc-4-aminomethylpiperi... 4-(Aminomethyl)-1-(tert-butoxycarbonyl)piperidine, tert-Butyl 4-(aminomethyl)piperidine-1-carboxylate 1,1-DiMethylethyl 4-(aMinoMethyl)-1-piperidinecarboxylate 1-tert-Butoxycarbonyl-4-piperidineMethanaMine 4-(AMinoMethyl)-N-boc-piperidine 4-AMinoMethyl-1-N-(tert-butoxycarbon 1-Boc-4-aMinoMethylpiperdine N-(tert-Butoxycarbonyl)-4-aminomethylpiperidine 4-(aminomethyl)-1-piperidinecarboxylic acid tert-butyl ester 4-(AMINOMETHYL)-1-N-BOC-PIPERIDINE 4-AMINOMETHYL-1-BOC-PIPERIDINE 4-(AMINOMETHYL)-BOC-PIPERIDINE 4-(AMINOMETHYL)-1-(TERT-BUTOXYCARBONYL)PIPERIDINE 4-AMINOMETHYL-1-N-(T-BUTOXYCARBONYL)PIPERIDINE 4-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-T-BUTYLOXYCARBONYL-4-AMINOMETHYL-PIPERIDINE 1-Boc-4-(aminomethyl)piperidine≥ 98% (HPLC) TERT-BUTYL-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE TERT-BUTYL 4-(AMINOMETHYL)TETRAHYDROPYRIDINE-1(2H)-CARBOXYLATE N-BOC-(4-AMINOMETHYL)PIPERIDINE 1-BOC-4-PIPERIDYLMETHYLAMINE 1-BOC-4-(AMINOMETHYL)PIPERIDINE 1-PIPERIDINECARBOXYLIC ACID, 4-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER 4-(AMINOMETHYL)-1-N-BOC-PIPERIDINE(50% in MeOH) BOC-4-(AMINOMETHYL)-PIPERIDINE BOC-PIP(4-AM) BUTTPARK 90\06-09 1-N-Boc-4-(aminomethyl)piperidine 4-(Aminomethyl)piperidine, N-BOC protected 1-TERT-BUTOXYCARBONYL-4-AMINOMETHYLPIPERIDINE N’-BOC-4-aminomethylpirrolidine 4-(Aminomethyl)piperidine, N-BOC protected 97% 1-N-BOC-4-(AMINOMETHYL)PIPERIDINE,98% 4-Aminomethyl-1-Boc piperidine In MeOH N-BOC-(4-aminomethyl)piperidine, 95 % min. 4-(Aminomethyl)-1-tert-butoxycarbonylpiperidine > )piperidine-1-carboxyL tert-Butyl 4-(Aminomethyl)-1-piperidinecarboxylate {1-[(tert-butoxy)carbonyl]piperidin-4-yl}methanaminium CAS:144222-22-0 4-(Aminomethyl)piperidine, N1-BOC protected tert-Butyl 4-(aminomethyl)piperidin-1-carboxylate 144222-22-0 14422-22-0 Building Blocks Heterocyclic Building Blocks Piperidines Heterocyclic Compounds Building Blocks Heterocyclic Building Blocks Piperidines pharmacetical Piperidine