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| | 1-Boc-4-(aminomethyl)piperidine Basic information |
| | 1-Boc-4-(aminomethyl)piperidine Chemical Properties |
| Boiling point | 237-238 °C(lit.) | | density | 1.013 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.473(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in chloroform and methanol. | | form | Liquid or Low Melting Solid | | pka | 10.13±0.29(Predicted) | | color | Colorless to yellow | | InChI | InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3 | | InChIKey | KLKBCNDBOVRQIJ-UHFFFAOYSA-N | | SMILES | N1(C(OC(C)(C)C)=O)CCC(CN)CC1 | | CAS DataBase Reference | 144222-22-0(CAS DataBase Reference) |
| | 1-Boc-4-(aminomethyl)piperidine Usage And Synthesis |
| Chemical Properties | White Low Melting Solid | | Uses | 1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds. | | Uses | 1-Boc-4-(aminomethyl)piperidine is used in the preparation biologically active compounds and orally active platelet-activating factor antagonists. It is used as an inhibitor for Kinesin spindle protein. It is an active reactant involved in the enantioselective synthesis of N-alkyl terminal aziridines.Precursor in the preparation of a variety of different protein agonists or antagonists including: Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential, Pim-1 inhibitors, and Aspartic acid protease inhibitors. | | Synthesis | 1-Boc-4-aminomethylpiperidine is an organic intermediate that can be prepared from tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate in three steps. |
| | 1-Boc-4-(aminomethyl)piperidine Preparation Products And Raw materials |
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