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N,N-Diethyl-2-phenylacetamide

CAS No.
2431-96-1
Chemical Name:
N,N-Diethyl-2-phenylacetamide
Synonyms
DEPA;n,n-diethylphenylacetamide;n,n-diethylbenzeneacetamide;Diethyl phenyl acetamide;phenyl-n,n-diethylacetamide;n,n-diethyl-benzeneacetamid;N,N-Diethyl-2-phenylacetamide;n,n-diethyl-2-phenyl-acetamid;BenzeneacetaMide, N,N-diethyl-;N,N-diethyl-2-phenyl-ethanamide
CBNumber:
CB7411232
Molecular Formula:
C12H17NO
Molecular Weight:
191.27
MDL Number:
MFCD00192031
MOL File:
2431-96-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:56

N,N-Diethyl-2-phenylacetamide Properties

Melting point 84-86 °C
Boiling point 169-171 °C18 mm Hg(lit.)
Density 1.004 g/mL at 25 °C(lit.)
refractive index n20/D 1.522(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly),Methanol (Slightly)
form Oil
pka -0.44±0.70(Predicted)
color Clear Colorless
FDA UNII TTI4PYU0SH

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
RTECS  AB7410000
Toxicity LD50 in guinea pigs, rats, rabbits, mice (g/kg): 7, 3-4, 3.5, ~2 dermally (Rao, 1991)

N,N-Diethyl-2-phenylacetamide price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-D444705-1G N,N-Diethylphenylacetamide 2431-96-1 1g $205 2026-06-03 Buy
TRC TRC-D444705-10G N,N-Diethylphenylacetamide 2431-96-1 10g $1611 2026-06-03 Buy
Activate Scientific AS119863 N,N-Diethyl-2-phenylacetamide 97% 2431-96-1 1g $65 2026-06-04 Buy
Activate Scientific AS119863 N,N-Diethyl-2-phenylacetamide 97% 2431-96-1 5g $107 2026-06-04 Buy
Activate Scientific AS119863 N,N-Diethyl-2-phenylacetamide 97% 2431-96-1 25g $478 2026-06-04 Buy
Product number Packaging Price Buy
TRC-D444705-1G 1g $205 Buy
TRC-D444705-10G 10g $1611 Buy
AS119863 1g $65 Buy
AS119863 5g $107 Buy
AS119863 25g $478 Buy

N,N-Diethyl-2-phenylacetamide Chemical Properties, Uses, Production

Description

N, N-DIETHYL-2-PHENYLACETAMIDE is a safe and effective, low-cost and broad-spectrum repellent for personal protection against Hematophagous arthropods1. It has repellent activity against hematophagous insects including mosquitoes, black flies, horse flies, muscoid flies, rat fleas, and ticks, as well as land leeches and cockroaches.As an Insect repellents, it exert its effects through interactions with Ors (odorant receptors) and GRs (gustatory receptor neuron (GRN)) in mosquitoes. However, the detailed mechanism of action remains inconclusive.

Referrence

  1. Kalyanasundaram, Muthuswami, and N. Mathew. "N,N-Diethyl Phenylacetamide (DEPA): A Safe and Effective Repellent for Personal Protection Against Hematophagous Arthropods." Journal of Medical Entomology 43.3(2013):518-25.
  2. Rao, S. S., and K. M. Rao. "Insect Repellent N, N-diethylphenylacetamide: An Update." Journal of Medical Entomology 8.3(1991):303.
  3. Dickens, Joseph C., and J. D. Bohbot. "Mini review: Mode of action of mosquito repellents." Pesticide Biochemistry & Physiology 106.3(2013):149-155.

Uses

Insect repellent.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 1215, 1981 DOI: 10.1021/jo00319a037

Metabolic pathway

When rats are exposed to whole-body attack by diethylphenylacetamide (DEPA), DEPA enters the systemic circulation when it is inhaled, and crosses air lung and lung blood barriers to be biodegraded and excreted. DEPA is converted by dealkylation and hydrolysis to the two acetamides, ethylphenylacetamide (EPA) and phenylacetamide (PA), and to phenylacetic acid (PhAA) which are excreted and identified as urinary metabolites.

109-89-7
103-80-0
2431-96-1
Synthesis of N,N-Diethyl-2-phenylacetamide from Diethylamine and Phenylacetyl chloride

N,N-Diethyl-2-phenylacetamide Preparation Products And Raw materials

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 997 58
Shanghai Hekang Biotechnology Co., Ltd. 17721021104 18939837085 2880152141@qq.com China 1840 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Shanghai Na Qian Chemical Technology Co. Ltd. 13598610367 13598610367 2841375912@qq.com China 3776 52
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Grice Rand (Tianjin) Pharmaceutical Co., Ltd. 022-83705301 13752403750 2966024760@qq.com China 814 55

View Latest Price from N,N-Diethyl-2-phenylacetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N-Diethyl-2-Phenylacetamide pictures 2023-05-27 N,N-Diethyl-2-Phenylacetamide
2431-96-1
$150.00 1kg 99.99% 50000tons Henan Bao Enluo International TradeCo.,LTD
N,N-Diethyl-2-phenylacetamide pictures 2022-01-15 N,N-Diethyl-2-phenylacetamide
2431-96-1
1KG 99.1% 100 tons Honest Joy Holdings Limited

N,N-Diethyl-2-phenylacetamide Spectrum

n,n-diethyl-2-phenyl-acetamid n,n-diethyl-benzeneacetamid n,n-diethylbenzeneacetamide phenyl-n,n-diethylacetamide DEPA(N,N-Diethyl-2-phenylacetamide) N,N-diethyl-2-phenyl-ethanamide BenzeneacetaMide, N,N-diethyl- Diethyl phenyl acetamide DEPA n,n-diethylphenylacetamide N,N-Diethyl-2-phenylacetamide 2431-96-1 C6H5CH2CONC2H52 Carbonyl Compounds Building Blocks Amides Organic Building Blocks Amides Carbonyl Compounds Organic Building Blocks