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Fmoc-L-2-furylalanine

CAS No.
159611-02-6
Chemical Name:
Fmoc-L-2-furylalanine
Synonyms
FMOC-ALA(2-FURYL)-OH;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-FURYLALANINE-L-PHENYLALANINE;Fmoc-L-2-FUA;RARECHEM BK PT 0223;Fmoc-L-2-furylalanine;FMOC-3-ALA(2-FURYL)-OH;(S)-N-FMOC-FURYLALANINE;fmoc-β-(2-furyl)-ala-oh;Fmoc-β-(2-furyl)-Ala-OH;Fmoc-3-L-Ala(2-furyl)-OH
CBNumber:
CB7426876
Molecular Formula:
C22H19NO5
Molecular Weight:
377.39
MDL Number:
MFCD01311747
MOL File:
159611-02-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:56

Fmoc-L-2-furylalanine Properties

Melting point 129.7 °C
Boiling point 505.72°C (rough estimate)
Density 1.318
refractive index 1.5614 (estimate)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 3.62±0.10(Predicted)
form Solid
color White to Off-White
CAS DataBase Reference 159611-02-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Hazard Codes  Xi
Safety Statements  22-24/25
WGK Germany  3
HS Code  2932190090

Fmoc-L-2-furylalanine price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F1013 N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-L-alanine >98.0%(T) 159611-02-6 200mg $73 2025-07-31 Buy
TCI Chemical F1013 N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-L-alanine >98.0%(T) 159611-02-6 1g $290 2025-07-31 Buy
Usbiological 277364 Fmoc-beta-(2-furyl)-L-alanine Asreported 159611-02-6 500mg $355 2026-06-03 Buy
Usbiological 277364 Fmoc-beta-(2-furyl)-L-alanine Asreported 159611-02-6 1g $612 2026-06-03 Buy
Usbiological 277364 Fmoc-beta-(2-furyl)-L-alanine Asreported 159611-02-6 2g $858 2026-06-03 Buy
Product number Packaging Price Buy
F1013 200mg $73 Buy
F1013 1g $290 Buy
277364 500mg $355 Buy
277364 1g $612 Buy
277364 2g $858 Buy

Fmoc-L-2-furylalanine Chemical Properties, Uses, Production

Chemical Properties

white to off-white powder

Uses

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid is an alanine derivative[1].

Synthesis

2-Furanpropanoic acid, α-amino-, methyl ester, (αS)-

146725-85-1

9-Fluorenylmethyl chloroformate

28920-43-6

FMOC-L-2-FURYLALANINE

159611-02-6

Methyl (S)-2-amino-3-(furan-2-yl)propanoate (1 g, 6.5 mmol) was dissolved in toluene as the starting material. 2M LiOH aqueous solution (3.27 ml, 6.5 mmol) and dioxane (3.27 ml) were slowly added to the reaction system at 0 °C under nitrogen protection and the reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by TLC (Spreader: CHCl3/MeOH/NH3 aqueous solution = 1/1/0.1) to confirm complete hydrolysis of the ester group. Subsequently, 1M aqueous NaHCO3 (9.75 ml, 9.75 mmol) dissolved in dioxane (10 ml) and methyl 9-fluorenyl chloroformate (2.5 g, 9.75 mmol) were added to the reaction solution and stirring was continued for 1 hour. After completion of the reaction, the dioxane was removed by distillation under reduced pressure and the remaining aqueous phase was acidified with 10% KHSO4 solution to pH=2. The aqueous phase was extracted with CHCl3 (3×20 ml), the organic phases were combined and dried over anhydrous MgSO4. After concentration under reduced pressure, the target product (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid (1.3 g, 53% yield) was purified by fast column chromatography (eluent: hexane/ethyl acetate/acetic acid=10/10/1) as white crystals. The product was characterized by 1H NMR and 13C NMR and the data were consistent with the expected structure.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

146725-85-1
28920-43-6
159611-02-6
Synthesis of Fmoc-L-2-furylalanine from 2-Furanpropanoic acid, α-amino-, methyl ester, (αS)- and 9-Fluorenylmethyl chloroformate

Fmoc-L-2-furylalanine Preparation Products And Raw materials

Global Suppliers ( 136)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shanghai HC Biotech Co., Ltd 021-20227858 sale@hcbiotech.com.cn China 1173 55
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Suzhou haiyu Biochem Industrial Co., LTD 512-68097639 18013585858 744942877@qq.com China 915 62
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shenzhen Sungening Bio-Tech Co., Ltd +86-0755-89668383 sales@sungening.com China 1319 65
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75

View Latest Price from Fmoc-L-2-furylalanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FMOC-L-2-FURYLALANINE pictures 2019-07-06 FMOC-L-2-FURYLALANINE
159611-02-6
$1.00 1kg 98% 100KG Career Henan Chemical Co

Fmoc-L-2-furylalanine Spectrum

(S)-2-(FMOC-AMINO)-3-(2-FURYL)PROPIONIC ACID (S)-N-FMOC-(2-FURYL)ALANINE (S)-N-FMOC-FURYLALANINE RARECHEM BK PT 0223 N-(9-FLUORENYLMETHOXYCARBONYL)-2-FURYL-L-ALANINE FMOC-3-ALA(2-FURYL)-OH FMOC-3-(2-FURYL)-L-ALANINE FMOC-BETA-(2-FURYL)-L-ALANINE Fmoc-beta-(2-furyl)-Ala-OH Fmoc-L-3-(2-Furyl)-alanine (S)-N-FMOC-(2-FURYL)ALANINE 95%(98%E.E.) fmoc-β-(2-furyl)-ala-oh 3-Fur-2-yl-L-alanine, N-FMOC protected (S)-N-FMOC-(2-FURYL)ALANINE 98+% (S)-2-(Fmoc-amino)-3-(2-furyl)propionicacid, Fmoc-3-(2-furyl)-L-alanine (alphaS)-alpha-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-furanpropanoic acid (S)-alpha-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-furanpropanoic acid (2S)-2-{[(9H-fluoren-9-ylMethoxy)carbonyl]aMino}-3-(2-furyl)propanoic acid (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(furan-2-yl)propanoic acid Fmoc-?-(2-furyl)-L-alanine99% Fmoc-3-L-Ala(2-furyl)-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-L-alanine (9H-Fluoren-9-yl)MethOxy]Carbonyl L-2-Furylalanine (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(furan-2-yl)propanoic acid (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-(2-furanyl)propanoate (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-furanpropanoic acid Fmoc-L-2-FUA N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-L-alanine> 2-Furanpropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αS)- N-Fmoc-3-(2-furyl)-L-alanine Fmoc-β-(2-furyl)-L-alanine 2-Furanpropanoic acid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,(aS)- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(furan-2-yl)propanoicaci Fmoc-β-(2-furyl)-Ala-OH, CAS 159611-02-6 Fmoc-β-(2-furyl)-Ala-OH FMOC-ALA(2-FURYL)-OH N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-FURYLALANINE-L-PHENYLALANINE Fmoc-L-2-furylalanine 159611-02-6 Alanine Derivatives Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Phenylalanine analogs and other aromatic alpha amino acids a-amino Amino Acids