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2-PHENYL-ETHANESULFONYL CHLORIDE

2-PHENYL-ETHANESULFONYL CHLORIDE structure

CAS No.: 4025-71-2

Chemical Name:: 2-PHENYL-ETHANESULFONYL CHLORIDE

Synonyms: Benzeneethanesulfonyl chloride;2-Phenyl-Ethanesulfonyl Chlorid;2-PHENYL-ETHANESULFONYL CHLORIDE;2-phenylethane-1-sulfonyl chloride;2-Phenyl-ethanesulfonyl chloride ,95%

CBNumber:: CB7444803

Molecular Formula:: C8H9ClO2S

Molecular Weight:: 204.67

MDL Number:: MFCD04117454

MOL File:: 4025-71-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:56:55

Product description	Number	Pack Size	Price
2-Phenylethanesulfonyl chloride 95+%	P38151	250mg	$60.44
2-Phenylethanesulfonyl chloride 95+%	P38151	1g	$80
2-Phenylethanesulfonyl chloride 95+%	P38151	5g	$180
2-Phenylethanesulfonyl chloride 95+%	P38151	10g	$280
2-Phenylethanesulfonyl chloride 95+%	P38151	25g	$730
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2-PHENYL-ETHANESULFONYL CHLORIDE Properties

Melting point	32-33 °C
Boiling point	121-123 °C(Press: 3 Torr)
Density	1.323±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
Appearance	White to light yellow <32°C Solid,>33°C Liquid
InChI	InChI=1S/C8H9ClO2S/c9-12(10,11)7-6-8-4-2-1-3-5-8/h1-5H,6-7H2
InChIKey	LKFNLHZZPHHFEC-UHFFFAOYSA-N
SMILES	C1(CCS(Cl)(=O)=O)=CC=CC=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501
RIDADR	1759
HazardClass	IRRITANT
PackingGroup	Ⅲ
Limited Quantities	5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities	Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

2-PHENYL-ETHANESULFONYL CHLORIDE price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	P38151	2-Phenylethanesulfonyl chloride 95+%	4025-71-2	250mg	$60.44	2026-05-06	Buy
Synthonix	P38151	2-Phenylethanesulfonyl chloride 95+%	4025-71-2	1g	$80	2026-05-06	Buy
Synthonix	P38151	2-Phenylethanesulfonyl chloride 95+%	4025-71-2	5g	$180	2026-05-06	Buy
Synthonix	P38151	2-Phenylethanesulfonyl chloride 95+%	4025-71-2	10g	$280	2026-05-06	Buy
Synthonix	P38151	2-Phenylethanesulfonyl chloride 95+%	4025-71-2	25g	$730	2026-05-06	Buy

Product number	Packaging	Price	Buy
P38151	250mg	$60.44	Buy
P38151	1g	$80	Buy
P38151	5g	$180	Buy
P38151	10g	$280	Buy
P38151	25g	$730	Buy

2-PHENYL-ETHANESULFONYL CHLORIDE Chemical Properties,Uses,Production

Synthesis

4410-99-5

4025-71-2

Example 15 Synthesis of 2-phenylethanesulfonyl chloride: N-chlorosuccinimide (534 mg, 4.00 mmol) was dissolved in a 2M HCl-CH3CN mixed solvent (267.4 μL - 1.34 mL, 3v/w volume relative to N-chlorosuccinimide). To this solution, a CH3CN solution (267.4 μL, 0.5 v/w relative to the volume of N-chlorosuccinimide) of 2-phenylethanethiol (134 μL, 1.00 mmol) was slowly added at 10 °C. After 30 min of reaction, ether was added to the reaction mixture, followed by three extractions with brine. The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-phenylethanesulfonyl chloride (195.5 mg, 95.4% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 7.43-7.27 (m, 5H), 3.98-3.92 (m, 3H), 3.41-3.35 (m, 1H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 8, p. 1181 - 1184
[2] Patent: US2015/329533, 2015, A1. Location in patent: Paragraph 0147; 0148
[3] Advanced Synthesis and Catalysis, 2015, vol. 357, # 18, p. 3825 - 3830
[4] Journal of Medicinal Chemistry, 2016, vol. 59, # 7, p. 3183 - 3203
[5] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2259 - 2263

2-PHENYL-ETHANESULFONYL CHLORIDE Preparation Products And Raw materials

Raw materials

Phenylacetic acid [(2-phenylethyl)sulfanyl]methanimidamide hydrobromide (2-Bromoethyl)benzene 2-Phenylethanethiol Hydrochloric acid

Acetonitrile N-Chlorosuccinimide

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Preparation Products

2-PHENYL-ETHANESULFONYL CHLORIDE Suppliers

Global( 75)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13902	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58

View Lastest Price from 2-PHENYL-ETHANESULFONYL CHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-26	2-PHENYL-ETHANESULFONYL CHLORIDE 4025-71-2	US $1.00 / KG	1KG	99%	1000KGS	Career Henan Chemical Co

2-PHENYL-ETHANESULFONYL CHLORIDE
4025-71-2
US $1.00 / KG
99%
Career Henan Chemical Co

2-PHENYL-ETHANESULFONYL CHLORIDE Spectrum

2-PHENYL-ETHANESULFONYL CHLORIDE(4025-71-2)¹HNMR

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2-PHENYL-ETHANESULFONYL CHLORIDE 2-Phenyl-ethanesulfonyl chloride ,95% 2-phenylethane-1-sulfonyl chloride Benzeneethanesulfonyl chloride 2-Phenyl-Ethanesulfonyl Chlorid 4025-71-2