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ChemicalBook >> CAS DataBase List >>1207629-49-9 (free)

1207629-49-9 (free)

1207629-49-9 (free) Structure
1207629-49-9 (free) structure
CAS No.
1325212-97-2
Chemical Name:
1207629-49-9 (free)
Synonyms
GSK-2245035 maleate;GSK-2245035 1325212-97-2
CBNumber:
CB74694725
Molecular Formula:
C24H38N6O6
Molecular Weight:
506.6
MDL Number:
MOL File:
1325212-97-2.mol
Last updated:2026-07-27 17:00:41
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1207629-49-9 (free) Properties

FDA UNII P7H1142RHT

1207629-49-9 (free) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA024AJK GSK-2245035 MALEATE 98+% 1325212-97-2 1mg $249 2026-06-01 Buy
Product number Packaging Price Buy
AA024AJK 1mg $249 Buy

1207629-49-9 (free) Chemical Properties, Uses, Production

Uses

GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma[1].

References

[1] Biggadike K, et al. Discovery of 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma. J Med Chem. 2016 Mar 10;59(5):1711-26. DOI:10.1021/acs.jmedchem.5b01647

1207629-49-9 (free) Preparation Products And Raw materials

Raw materials

Preparation Products

1207629-49-9 (free) Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29873 58
Shanghai Anbida Biotechnology Co., Ltd. 021-61629020 18201956406 sales@ambeed.cn China 7032 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Shanghai Anbida Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from 1207629-49-9 (free) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GSK-2245035 maleate pictures 2026-07-27 GSK-2245035 maleate
1325212-97-2
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

1325212-97-2 (1207629-49-9 (free)) Related Search:

GSK2245035 8H-Purin-8-one, 6-amino-2-butoxy-7,9-dihydro-9-(phenylmethyl)- 1207629-49-9 (free) Butanoic acid, 4-[[[4-[[6-amino-7,8-dihydro-2-(2-methoxyethoxy)-8-oxo-9H-purin-9-yl]methyl]phenyl]methyl]amino]-4-oxo- Infliximab
Lipopolysaccharides, from E. coli O55:B5

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GSK-2245035 1325212-97-2 GSK-2245035 maleate 1325212-97-2