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ChemicalBook >> CAS DataBase List >>N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide Structure
N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide structure
CAS No.
1292285-54-1
Chemical Name:
N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide
Synonyms
SPRi 3;SPR inhibitor 3;N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide;Acetamide, N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-
CBNumber:
CB74902897
Molecular Formula:
C14H18N2O3
Molecular Weight:
262.3
MDL Number:
MFCD32215304
MOL File:
1292285-54-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide Properties

Boiling point 561.9±50.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 100 mM,Ethanol: 100 mM
form A solid
pka 10.14±0.40(Predicted)
color Off-white to gray

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30950 SPRi 3 ≥98% 1292285-54-1 1mg $49 2026-04-30 Buy
Cayman Chemical 30950 SPRi 3 ≥98% 1292285-54-1 5mg $213 2026-04-30 Buy
Biosynth SBC28554 SPRi 3 1292285-54-1 25mg $1149.25 2026-06-05 Buy
Biosynth SBC28554 SPRi 3 1292285-54-1 50mg $1428 2026-06-05 Buy
Biosynth SBC28554 SPRi 3 1292285-54-1 100mg $1785 2026-06-05 Buy
Product number Packaging Price Buy
30950 1mg $49 Buy
30950 5mg $213 Buy
SBC28554 25mg $1149.25 Buy
SBC28554 50mg $1428 Buy
SBC28554 100mg $1785 Buy

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide Chemical Properties, Uses, Production

Uses

SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3].

storage

Store at -20°C

References

[1] Latremoliere A, et al. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron. 2015 Jun 17;86(6):1393-406. DOI:10.1016/j.neuron.2015.05.033
[2] Cronin SJF, et al. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2018 Nov;563(7732):564-568. DOI:10.1038/s41586-018-0701-2
[3] Haruki H, et al. Tetrahydrobiopterin Biosynthesis as a Potential Target of the Kynurenine Pathway Metabolite Xanthurenic Acid. J Biol Chem. 2016 Jan 8;291(2):652-7. DOI:10.1074/jbc.C115.680488

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 4000862158 18117107507 vip@med-life.cn China 4999 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Rechem science Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58

View Latest Price from N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SPR inhibitor 3 pictures 2026-07-15 SPR inhibitor 3
1292285-54-1
 $67.00-175.00 10g TargetMol Chemicals Inc.

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N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide SPR inhibitor 3 SPRi 3 Acetamide, N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy- 1292285-54-1