CD437
- CAS No.
- 125316-60-1
- Chemical Name:
- CD437
- Synonyms
- CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;O-demethyladaparine;CD437;CD-437;CD 437;Adapalene IMpurity F
- CBNumber:
- CB7503287
- Molecular Formula:
- C27H26O3
- Molecular Weight:
- 398.49
- MDL Number:
- MFCD03106506
- MOL File:
- 125316-60-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| CD437 ≥98% (HPLC), solid | C5865 | 5mg | $284 |
| Apoptosis Activator VI, CD437/AHPN | 178496 | 5mg | $195 |
| CD 437 | A3612 | 10MG | $143 |
| CD437 ≥95% | 71610 | 5mg | $95 |
| CD437 ≥95% | 71610 | 10mg | $128 |
| More product size | |||
| Melting point | 271.6-276 °C |
|---|---|
| Boiling point | 595.0±50.0 °C(Predicted) |
| Density | 1.290 |
| storage temp. | -20°C |
| solubility | DMSO: 26 mg/mL |
| form | solid |
| pka | 4.17±0.30(Predicted) |
| color | yellow |
| InChI | 1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30) |
| InChIKey | LDGIHZJOIQSHPB-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | QJ1975900 |
| Storage Class | 11 - Combustible Solids |
CD437 price More Price(84)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5865 | CD437 ≥98% (HPLC), solid | 125316-60-1 | 5mg | $284 | 2026-04-30 | Buy |
| Sigma-Aldrich | 178496 | Apoptosis Activator VI, CD437/AHPN | 125316-60-1 | 5mg | $195 | 2026-04-30 | Buy |
| TCI Chemical | A3612 | CD 437 | 125316-60-1 | 10MG | $143 | 2026-04-30 | Buy |
| Cayman Chemical | 71610 | CD437 ≥95% | 125316-60-1 | 5mg | $95 | 2026-04-30 | Buy |
| Cayman Chemical | 71610 | CD437 ≥95% | 125316-60-1 | 10mg | $128 | 2026-04-30 | Buy |
CD437 Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
An intermediate in the preparation of Adapalene derivatives.
Definition
ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.
Biological Activity
Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.
Biochem/physiol Actions
CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.
storage
Store at -20°C
CD437 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9935 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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