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CD437

CAS No.
125316-60-1
Chemical Name:
CD437
Synonyms
CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;O-demethyladaparine;CD437;CD-437;CD 437;Adapalene IMpurity F
CBNumber:
CB7503287
Molecular Formula:
C27H26O3
Molecular Weight:
398.49
MDL Number:
MFCD03106506
MOL File:
125316-60-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
CD437 ≥98% (HPLC), solid C5865 5mg $284
Apoptosis Activator VI, CD437/AHPN 178496 5mg $195
CD 437 A3612 10MG $143
CD437 ≥95% 71610 5mg $95
CD437 ≥95% 71610 10mg $128
More product size

CD437 Properties

Melting point 271.6-276 °C
Boiling point 595.0±50.0 °C(Predicted)
Density 1.290
storage temp. -20°C
solubility DMSO: 26 mg/mL
form solid
pka 4.17±0.30(Predicted)
color yellow
InChI 1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey LDGIHZJOIQSHPB-UHFFFAOYSA-N
SMILES OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
RTECS  QJ1975900
Storage Class 11 - Combustible Solids

CD437 price More Price(84)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5865 CD437 ≥98% (HPLC), solid 125316-60-1 5mg $284 2026-04-30 Buy
Sigma-Aldrich 178496 Apoptosis Activator VI, CD437/AHPN 125316-60-1 5mg $195 2026-04-30 Buy
TCI Chemical A3612 CD 437 125316-60-1 10MG $143 2026-04-30 Buy
Cayman Chemical 71610 CD437 ≥95% 125316-60-1 5mg $95 2026-04-30 Buy
Cayman Chemical 71610 CD437 ≥95% 125316-60-1 10mg $128 2026-04-30 Buy
Product number Packaging Price Buy
C5865 5mg $284 Buy
178496 5mg $195 Buy
A3612 10MG $143 Buy
71610 5mg $95 Buy
71610 10mg $128 Buy

CD437 Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the preparation of Adapalene derivatives.

Definition

ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.

Biological Activity

Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.

Biochem/physiol Actions

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

storage

Store at -20°C

CD437 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 138)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Fuxin Pharmaceutical
+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 sales@sarms4muscle.com China 10378 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +86-15965530500 nickzhang@hangyubiotech.com China 9935 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20111 58
Aladdin Scientific
tp@aladdinsci.com United States 54746 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76

View Lastest Price from CD437 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CD437 pictures 2026-07-15 CD437
125316-60-1
$34.00-89.00 99.56% 10g TargetMol Chemicals Inc.
CD 437 pictures 2020-01-13 CD 437
125316-60-1
$1.00 1g 95-99% 1ton Career Henan Chemical Co
  • CD437 pictures
  • CD437
    125316-60-1
  • $34.00-89.00
  • 99.56%
  • TargetMol Chemicals Inc.
  • CD 437 pictures
  • CD 437
    125316-60-1
  • $1.00
  • 95-99%
  • Career Henan Chemical Co

CD437 Spectrum

2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen 6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid O-DesMethyl Adapalene CD 437/AHPN Adapalene IMpurity F Apoptosis Activator VI, CD437/AHPN ADAP-IME 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid CS-2691 O-Desmethyl Adapalene-13C6 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem AHPN;CD 437;CD-437 Apoptosis Activator VI 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthoic Acid 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)- 6-(3-(Adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid inhibit,Retinoid X receptors,CD437,CD-437,CD 437,RAR/RXR,Inhibitor,Autophagy,Retinoic acid receptors Ro 472077 Ro472077 Ro-472077 O-demethyladaparine CD 437, RARgamma-selective agonist. CD437;CD-437;CD 437 CD437/6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid CD437, 10 mM in DMSO 125316-60-1 Aromatics Intermediates & Fine Chemicals Pharmaceuticals