(E)-cyclooct-4-enol / axial - TCO4 / A
- CAS No.
- 39637-78-0
- Chemical Name:
- (E)-cyclooct-4-enol / axial - TCO4 / A
- Synonyms
- (R)-TCO-OH;(R)-Cyclooct-4-en-1-ol;4-Cycloocten-1-ol, (1R)-;(E)-cyclooct-4-enol / axial - TCO / A;(E)-cyclooct-4-enol / axial - TCO4 / A
- CBNumber:
- CB75857181
- Molecular Formula:
- C8H14O
- Molecular Weight:
- 126.2
- MDL Number:
- MOL File:
- 39637-78-0.mol
(E)-cyclooct-4-enol / axial - TCO4 / A Chemical Properties, Uses, Production
Uses
(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (R)-TCO-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(E)-cyclooct-4-enol / axial - TCO4 / A Preparation Products And Raw materials
Raw materials
Preparation Products
(E)-cyclooct-4-enol / axial - TCO4 / A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Vicbio Biotechnology Co., Ltd. | 13621190864 13691409741 | info@vicbio.com | China | 13147 | 58 |
| Beijing Famozi Pharmaceutical Technology Co., Ltd | 15811073878 | 2559355526@qq.com | China | 9996 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
