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2-Methanesulfonyl-pyrimidine

2-Methanesulfonyl-pyrimidine Structure
2-Methanesulfonyl-pyrimidine structure
CAS No.
14161-09-2
Chemical Name:
2-Methanesulfonyl-pyrimidine
Synonyms
2-(Methylsulfonyl)pyrimidine;2-Methanesulfonyl-pyrimidine;Methyl pyrimidin-2-yl sulphone;Pyrimidine, 2-(methylsulfonyl)-;2-METHANESULFONYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber:
CB7684944
Molecular Formula:
C5H6N2O2S
Molecular Weight:
158.18
MDL Number:
MFCD06795939
MOL File:
14161-09-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:05
Request For Quotation

2-Methanesulfonyl-pyrimidine Properties

Boiling point 335.6±25.0 °C(Predicted)
Density 1.344±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka -3.39±0.13(Predicted)
form solid
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2933599590

2-Methanesulfonyl-pyrimidine price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 296312 2-Methanesulfonyl-pyrimidine Asreported 14161-09-2 250mg $375 2026-06-03 Buy
Usbiological 296312 2-Methanesulfonyl-pyrimidine Asreported 14161-09-2 500mg $523 2026-06-03 Buy
Usbiological 296312 2-Methanesulfonyl-pyrimidine Asreported 14161-09-2 1g $721 2026-06-03 Buy
Usbiological 296312 2-Methanesulfonyl-pyrimidine Asreported 14161-09-2 2g $991 2026-06-03 Buy
Usbiological 296312 2-Methanesulfonyl-pyrimidine Asreported 14161-09-2 5g $1380 2026-06-03 Buy
Product number Packaging Price Buy
296312 250mg $375 Buy
296312 500mg $523 Buy
296312 1g $721 Buy
296312 2g $991 Buy
296312 5g $1380 Buy

2-Methanesulfonyl-pyrimidine Chemical Properties, Uses, Production

Application

2-Methylsulfonylpyrimidine can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly in laboratory research and development processes and chemical and pharmaceutical synthesis processes.

Synthesis

2-Methylsulfonylpyrimidine was prepared as follows: a suspension of potassium carbonate (27.6 g, 0.2 mol) in a solution of 2-mercaptopyrimidine (0.1 mol) and methyl iodide (18.7 ml, 0.3 mol) in acetone (200 ml) was heated to reflux for a period of 3 hours. The reaction mixture was allowed to cool and then filtered followed by vacuum evaporation. Distillation of the mixture at a pressure of 0.01 mmHg gave 12.7 g of 2-methylthio-4,6-dimethylpyrimidine as a white solid. A portion of this solid (4.42 g, 28.7 mmol) was dissolved in dichloromethane (200 ml) and m-chloroperoxybenzoic acid (50%, 22.8 g, 66.0 mmol) was added in batches. The resulting mixture was stirred for 5 days and finally it was filtered and then evaporated under vacuum. Purification by rapid column chromatography on silica gel, using ether as eluent, gave 2-methylsulfonylpyrimidine as a white solid, m.pt., 81 C.

2-Methanesulfonyl-pyrimidine synthesis

823-09-6
7757-82-6
14161-09-2
Synthesis of 2-Methanesulfonyl-pyrimidine from 2-(Methylthio)pyrimidine and Sodium sulfate

2-Methanesulfonyl-pyrimidine Preparation Products And Raw materials

Raw materials

2-(Methylthio)pyrimidine Sodium sulfate

Preparation Products

DiMethyl 2-(2-PyriMidyl)Malonate

2-Methanesulfonyl-pyrimidine Suppliers

Global Suppliers ( 58)
Supplier Tel Email Country ProdList Advantage
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Supplier Advantage
TAIYUAN RHF CO.,LTD. 56
Wuhan Chemwish Technology Co., Ltd 56
Tetranov Biopharm 64
Nanjing Chemlin Chemical Co., Ltd 64
SynAsst Chemical. 55
Shanghai YuLue Chemical Co., Ltd. 55
Nanjing Chalf-Pharm Technology Co., Ltd. 50
SPIRO PHARMA 55
Amadis Chemical Company Limited 58
Capot Chemical Co.,Ltd. 60

View Latest Price from 2-Methanesulfonyl-pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-METHANESULFONYL-PYRIMIDINE pictures 2026-02-02 2-METHANESULFONYL-PYRIMIDINE
14161-09-2
 $1.00 1g 99% 20ton Shaanxi Dideu Medichem Co. Ltd
2-METHANESULFONYL-PYRIMIDINE pictures 2025-05-23 2-METHANESULFONYL-PYRIMIDINE
14161-09-2
 $50.00 1kg 99 5000 Hebei Zhuanglai Chemical Trading Co Ltd

2-Methanesulfonyl-pyrimidine Spectrum

2-METHANESULFONYL-PYRIMIDINE(14161-09-2)1HNMR

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Methyl pyrimidin-2-yl sulphone 2-METHANESULFONYL-PYRIMIDINE ISO 9001：2015 REACH Pyrimidine, 2-(methylsulfonyl)- 2-(Methylsulfonyl)pyrimidine 2-Methanesulfonyl-pyrimidine 14161-09-2