5-BROMO-2-METHANESULFONYL-PYRIMIDINE
- CAS No.
- 38275-48-8
- Chemical Name:
- 5-BROMO-2-METHANESULFONYL-PYRIMIDINE
- Synonyms
- NSC 262216;5-BROMO-2-METHANESULFONYL-PYRIMIDINE;5-Bromopyrimidin-2-yl methyl sulphone;Pyrimidine, 5-bromo-2-(methylsulfonyl)-;5-Bromo-2-(methylsulfonyl)pyrimidine 97%;5-
Bromo- 2- (methylsulfonyl) pyrimidine;5-BROMO-2-METHANESULFONYL-PYRIMIDINE ISO 9001：2015 REACH;5-Bromopyrimidin-2-yl methyl sulphone, 5-Bromo-2-(methylsulphonyl)-1,3-diazine
- CBNumber:
- CB9663127
- Molecular Formula:
- C5H5BrN2O2S
- Molecular Weight:
- 237.07
- MDL Number:
- MFCD00508247
- MOL File:
- 38275-48-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-(methylsulfonyl)pyrimidine 97% | 767093 | 1g | $252 |
| 5-Bromo-2-(methylsulphonyl)pyrimidine | B678015 | 10mg | $45 |
| 5-Bromo-2-(methylsulfonyl)pyrimidine | FB143269 | 500mg | $65 |
| 5-Bromo-2-(methylsulphonyl)pyrimidine | OR15516 | 1g | $74 |
| 5-Bromo-2-(methylsulfonyl)pyrimidine | 8H63-9-X4 | 1g | $82 |
| More product size | |||
| Melting point | 130-133°C |
|---|---|
| Boiling point | 393.7±34.0 °C(Predicted) |
| Density | 1.771±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | -4.78±0.22(Predicted) |
| form | crystalline powder |
| color | White |
| InChI | InChI=1S/C5H5BrN2O2S/c1-11(9,10)5-7-2-4(6)3-8-5/h2-3H,1H3 |
| InChIKey | MVIRMXABVKJKAR-UHFFFAOYSA-N |
| SMILES | C1(S(C)(=O)=O)=NC=C(Br)C=N1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
5-BROMO-2-METHANESULFONYL-PYRIMIDINE price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 767093 | 5-Bromo-2-(methylsulfonyl)pyrimidine 97% | 38275-48-8 | 1g | $252 | 2023-01-07 | Buy |
| TRC | B678015 | 5-Bromo-2-(methylsulphonyl)pyrimidine | 38275-48-8 | 10mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB143269 | 5-Bromo-2-(methylsulfonyl)pyrimidine | 38275-48-8 | 500mg | $65 | 2021-12-16 | Buy |
| Apolloscientific | OR15516 | 5-Bromo-2-(methylsulphonyl)pyrimidine | 38275-48-8 | 1g | $74 | 2021-12-16 | Buy |
| SynQuest Laboratories | 8H63-9-X4 | 5-Bromo-2-(methylsulfonyl)pyrimidine | 38275-48-8 | 1g | $82 | 2021-12-16 | Buy |
5-BROMO-2-METHANESULFONYL-PYRIMIDINE Chemical Properties,Uses,Production
Synthesis
14001-67-3
38275-48-8
The general procedure for the synthesis of 5-bromo-2-(methylsulfonyl)pyrimidine from 5-bromo-2-methylmercaptopyrimidine was as follows: 5-bromo-2-methylthiopyrimidine (10.0 g, 48.8 mmol) was dissolved in methanol (195 mL), to which was subsequently added in batch and in an alternating addition pattern Oxone?(94.6 g, 154 mmol, 3.16 eq.) in an aqueous solution (500 mL) and 4N aqueous sodium hydroxide solution (40 mL, 160 mmol, 3.28 eq.), the temperature was controlled and the pH was maintained between 2 and 3 during the reaction. After the addition was completed, the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, water (500 mL) was added to dilute and the mixture was extracted with ethyl acetate (2 x 500 mL). The aqueous layer was adjusted to pH 7 and extracted again with ethyl acetate. The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to afford 9.23 g (80% yield) of the target product, 5-bromo-2-(methylsulfonyl)pyrimidine, which could be used in the subsequent reaction without further purification. The product was characterized by 1H-NMR (300 MHz, DMSO-d6) and mass spectrometry (ESI): 1H-NMR δ 9.28 (s, 2H), 3.37 (s, 3H); MS (ESI): m/z [M + H]+ 237 (79Br).
References
[1] Patent: WO2008/155140, 2008, A1. Location in patent: Page/Page column 123-124
[2] Patent: WO2018/165520, 2018, A1. Location in patent: Page/Page column 137-138
5-BROMO-2-METHANESULFONYL-PYRIMIDINE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20284 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from 5-BROMO-2-METHANESULFONYL-PYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 5-BROMO-2-METHANESULFONYL-PYRIMIDINE
38275-48-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
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- 5-BROMO-2-METHANESULFONYL-PYRIMIDINE
38275-48-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
