7-Bromo-2-chloroquinoxaline
- CAS No.
- 89891-65-6
- Chemical Name:
- 7-Bromo-2-chloroquinoxaline
- Synonyms
- 3-chloro-6-bromoquinoxaline;7-BROMO-2-CHLOROQUINOXALINE;Quinoxaline, 7-bromo-2-chloro-
- CBNumber:
- CB7696729
- Molecular Formula:
- C8H4BrClN2
- Molecular Weight:
- 243.49
- MDL Number:
- MFCD02955309
- MOL File:
- 89891-65-6.mol
| Boiling point | 312.5±37.0 °C(Predicted) |
|---|---|
| Density | 1.762 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -2.50±0.30(Predicted) |
| Appearance | Off-white to light brown Solid |
| InChI | InChI=1S/C8H4BrClN2/c9-5-1-2-6-7(3-5)12-8(10)4-11-6/h1-4H |
| InChIKey | AZUMKBQKUXTHCM-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=C(Br)C=2)N=CC=1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2933998090 |
7-Bromo-2-chloroquinoxaline price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 52464 | 7-BROMO-2-CHLOROQUINOXALINE 97% | 89891-65-6 | 1G | $10 | 2026-04-30 | Buy |
| AstaTech | 52464 | 7-BROMO-2-CHLOROQUINOXALINE 97% | 89891-65-6 | 5G | $18 | 2026-04-30 | Buy |
| AstaTech | 52464 | 7-BROMO-2-CHLOROQUINOXALINE 97% | 89891-65-6 | 25G | $47 | 2026-04-30 | Buy |
| Apolloscientific | OR952570 | 7-Bromo-2-chloroquinoxaline 97% | 89891-65-6 | 1g | $21 | 2026-06-04 | Buy |
| Matrix Scientific | 073000 | 7-Bromo-2-chloroquinoxaline | 89891-65-6 | 25.00g | $44 | 2026-05-18 | Buy |
7-Bromo-2-chloroquinoxaline Chemical Properties, Uses, Production
Uses
7-Bromo-2-chloroquinoxaline is a heterocyclic derivative that can be used as an organic intermediate.
Synthesis
82031-32-1
89891-65-6
General procedure for the synthesis of 7-bromo-2-chloroquinoxaline from 7-bromo-2(1H)-quinoxalinone: 7-bromoquinoxalin-2-ol (2 g, 8.88 mmol) was added to dry phosphorus trichloride (7 mL) to form a suspension, followed by the addition of N,N-dimethylformamide (DMF, 2 drops). The reaction mixture was heated to 100 °C and the reaction was stirred at this temperature for 3 hours. After completion of the reaction, the mixture was cooled to room temperature. Excess phosphorous trichloride was evaporated under reduced pressure and the residue was dissolved in ethyl acetate (EtOAc) and added slowly dropwise to ice water under stirring. The aqueous phase was extracted three times with ethyl acetate, the organic layers were combined and washed with saturated sodium bicarbonate (NaHCO3) solution. Finally, the organic layer was concentrated to give 7-bromo-2-chloroquinoxaline as a solid product in 93% (2 g) yield.
References
[1] Journal of Medicinal Chemistry, 2011, vol. 54, # 13, p. 4735 - 4751
[2] Patent: WO2012/34526, 2012, A1. Location in patent: Page/Page column 34-35
[3] Patent: US2013/190307, 2013, A1. Location in patent: Paragraph 0162; 0164
[4] Patent: WO2017/32840, 2017, A1. Location in patent: Page/Page column 280
[5] Patent: WO2014/151147, 2014, A1. Location in patent: Paragraph 00641
7-Bromo-2-chloroquinoxaline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing AoShe Biological Chemical Co., Ltd. | 023-63225655 13320248848 | 2366581735@qq.com | China | 501 | 55 |
| Suzhou Lakestar Pharmatech Co., Ltd. | 0512-63970158-603 18018108880 | info@lakestarpharma.com | China | 400 | 59 |
| Shanghai Synteam Biochem CO.,ltd | +86-021-58380978 13482386415 | info@systeambc.com | China | 897 | 50 |
| Tianjin Zhongcheng Mingyuan Technology Co., Ltd. | 13302022156 | 3506745780@qq.com | China | 168 | 58 |
| Weifang Yuda Pharmaceutical Technology Co., Ltd. | 17663603912 | 2710256076@qq.com | China | 196 | 56 |
| Jinan New Synharmony PharmaTech Co., Ltd. | 13806405245 18560110739 | 1073692093@qq.com | China | 109 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 7-Bromo-2-chloroquinoxaline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 7-Bromo-2-chloroquinoxaline
89891-65-6
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-04-04 | 7-Bromo-2-chloroquinoxaline
89891-65-6
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
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 |
2019-12-23 | 7-Bromo-2-chloroquinoxaline
89891-65-6
|
$2.00 | 1KG | ≥98% | 100kg | Career Henan Chemical Co |
-
- 7-Bromo-2-chloroquinoxaline
89891-65-6
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 7-Bromo-2-chloroquinoxaline
89891-65-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 7-Bromo-2-chloroquinoxaline
89891-65-6
- $2.00
- ≥98%
- Career Henan Chemical Co
