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PROTAMINE SULFATE

CAS No.
9009-65-8
Chemical Name:
PROTAMINE SULFATE
Synonyms
Protamin sulfate;ProtaMine sulfates;PROTAMINE SULFATE SALT;Protamine sulfate, Salmine sulfate from salmon sperm;fluxema;usafd-4;SALMINE;dilangio;vasorelax;Ccris 8521
CBNumber:
CB7727744
Molecular Formula:
H2O4S
Molecular Weight:
0
MDL Number:
MFCD00132091
MOL File:
Mol file
Last updated:2026-01-22 09:05:13
Product description Number Pack Size Price
Protamine sulfate certified reference material, pharmaceutical secondary standard PHR2610 25MG $261

PROTAMINE SULFATE Properties

storage temp. -20°C
solubility H2O: 10 mg/mL
form amorphous powder
color white
Water Solubility It is sparingly soluble in water.
Sensitive Hygroscopic
Cosmetics Ingredients Functions SKIN CONDITIONING
FDA UNII 0DE9724IHC
EPA Substance Registry System Protamines, sulfates (9009-65-8)
UNSPSC Code 41116107
NACRES NB.21

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
RTECS  VO9470000
21-10
TSCA  TSCA listed
HS Code  35040090
Storage Class 11 - Combustible Solids

PROTAMINE SULFATE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2610 Protamine sulfate certified reference material, pharmaceutical secondary standard 9009-65-8 25MG $261 2025-07-31 Buy
Product number Packaging Price Buy
PHR2610 25MG $261 Buy

PROTAMINE SULFATE Chemical Properties,Uses,Production

Chemical Properties

White or almost white, hygroscopic powder.

Uses

It is suitable for personal care, cosmetic and pharmaceutical applications. It is used widely to reverse the anticoagulant effects of heparin. It acts as a heparin antagonist. It is also a weak anticoagulant. It may be used for the removal of DNA from protein samples or the purification of DNA binding proteins. Protamine sulfate may also be used as an alternative to polybrene in retroviral mediated gene transfer. Protamine sulfate has antibacterial properties and inhibits pepsin activity. Protamine sulfate and other polycations have been shown to inhibit the classical pathway of complement. It neutralizes the anticoagulant activity of heparin, and inhibits turnover of lipoproteins by lipoprotein lipase. The aggregation of erythrocytes in the presence of protamine sulfate, for application to the prediction of MN phenotypes, has been investigated.

Uses

Antidote (to heparin).

in vivo

Protamine sulfate can be used in animal modeling to create cystitis models[5].

Induction of cystitis model[5]
Background
The presence and activity of protamine sulfate may trigger the activation and inflammatory response of the host immune system. These immune responses can lead to the infiltration of inflammatory cells and the production of inflammatory mediators, such as cytokines and interleukins, which can lead to cystitis.
Specific Modeling Methods
Rat: Sprague-Dawley ? female &bull
Administration: 10 mg/mL irrigation in the urinary bladder ? once
Note
(1) 10 mg/ml protamine sulfate was injected into the rat bladder, and 2 mg/ml LPS was injected 30 minutes later
(2) 5 days later, the experimental animals were put to death under anesthesia, and the bladder was removed for observation.
Modeling Indicators
Physiological indicators: The turbidity, urine volume and the number of red blood cells in the urine of rats were detected.
Molecular changes: The levels of biomarkers IL-6, TNF-α and NF-κB in bladder tissues were detected.
Histological analysis: Hematoxylin and eosin staining were used to detect the number of mast cells in the bladder of rats.
Correlated Product(s): LPS (HY-D1056)
Opposite Product(s): /

PROTAMINE SULFATE Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAMINE SULFATE Suppliers

Global( 115)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21599 55
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 1287 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Qiuxian Baitai New Material Co., LTD
+8618330912755 sale2@hbyalin.com China 1658 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3388 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 19781 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 24705 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33325 58

View Lastest Price from PROTAMINE SULFATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PROTAMINE SULFATE pictures 2026-01-26 PROTAMINE SULFATE
9009-65-8
0.99 RongNa Biotechnology Co.,Ltd
Protamine sulfate pictures 2026-01-22 Protamine sulfate
9009-65-8
US $39.00-30.00 / mg 99.87% 10g TargetMol Chemicals Inc.
Protamine Sulfate pictures 2021-11-15 Protamine Sulfate
9009-65-8
US $200.00 / KG 100KG 98% 50ton/Month Qiuxian Baitai New Material Co., LTD
Protamin sulfate ProtamineSulphateExSalmonRoe PROTAMINE SULFATE SALT Protamine sulfate, Salmine sulfate from salmon sperm Protamine sulfate 1g [9009-65-8] Ccris 8521 Protamina solfato Protamina solfato [dcit] ProtaMine sulfates Protamine sulfate, from milt Protamine Sulfate From Salmon Sperm, Molecular biology Protemine Sulfate angiociclan dilangio fluxema Protamines,sulfates usafd-4 vasorelax CLUPEINE SULFATE SALMINE SALMINE SULFATE PROTAMINE SULFATE (EX SALMON) PROTAMINE SULFATE HERRING PROTAMINE SULFATE SALMON PROTAMINE SULFATE, SALMON MILT Protamine Sulfate, USP, EP Protamine sulfate (Y0002179) Protamine Sulfate (1578612) Protamne sulfate Protamine Sulfate (2.69 mg) Protamine sulfate ex salmonidae 9009-65-8 9002-65-8 Enzyme Inhibitors by Type Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Proteomics Protein Sample Clarification Proteomics and Protein Expression Sample Preparation Substrate Analogs Biochemicals and Reagents BioChemical Cell Lysis and Protein Extraction Reagents