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GLYCOFUROL

CAS No.
31692-85-0
Chemical Name:
GLYCOFUROL
Synonyms
TETRAGLYCOL;THFP;Glycofural;POLY(ETHYLENE GLYCOL) TETRAHYDROFURFURYL ETHER;GLYCOFUROL;TETRAGLYCO;GLYCOFUROL;Glycofurol75;Glycofurolum 75;GLYCOFUROL-SPECIAL
CBNumber:
CB7756948
Molecular Formula:
(C2H4O)nC5H10O2
Molecular Weight:
218.29
MDL Number:
MFCD00801146
MOL File:
31692-85-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:28:47

GLYCOFUROL Properties

Melting point ≤ -100 °C
Boiling point 100-145 °C0.4 mm Hg
Density 1.09 g/mL at 25 °C(lit.)
vapor pressure 4.97-37.4Pa at 20-50℃
refractive index n20/D 1.462(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Sparingly), Methanol (Slightly, Sonicated)
form Oil
color Colourless
Water Solubility water: soluble 3420g/L
α-end tetrahydrofurfuryl ether
Ω-end hydroxyl
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions SOLVENT
VISCOSITY CONTROLLING
InChI 1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
InChIKey CTPDSKVQLSDPLC-UHFFFAOYSA-N
LogP -1.21--0.38
FDA UNII YZC5LZ8BUB
UNSPSC Code 12352201
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
PPE Eyeshields, Gloves
WGK Germany  3
RTECS  MD0907500
HS Code  3907 20 20
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
REACH Registrations Active

GLYCOFUROL price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T3396 Tetraglycol BioXtra 31692-85-0 1kg $355 2026-04-30 Buy
Sigma-Aldrich 8.21092 Tetrahydrofurfuryl alcohol polyethylene glycol ether forsynthesis 31692-85-0 100mL $75.9 2026-04-30 Buy
Sigma-Aldrich 8.21092 Tetrahydrofurfuryl alcohol polyethylene glycol ether forsynthesis 31692-85-0 250ML $161 2026-04-30 Buy
Sigma-Aldrich 8.21092 Tetrahydrofurfuryl alcohol polyethylene glycol ether forsynthesis 31692-85-0 10Kg $1750 2026-04-30 Buy
Biosynth FG44950 Tetraglycol 31692-85-0 25g $295 2026-06-04 Buy
Product number Packaging Price Buy
T3396 1kg $355 Buy
8.21092 100mL $75.9 Buy
8.21092 250ML $161 Buy
8.21092 10Kg $1750 Buy
FG44950 25g $295 Buy

GLYCOFUROL Chemical Properties, Uses, Production

Chemical Properties

Glycofurol is a clear, colorless, almost odorless liquid, with a bitter taste; it produces a warm sensation on the tongue.

Uses

Glycofurol is used as a carrier device for drug delivery.

Uses

Used as solvent to dissolve water-insoluble compounds.

Production Methods

Glycofurol is prepared by the reaction of tetrahydrofurfuryl alcohol with ethylene oxide (followed by a special purification process in the case of Glycofurol 75).

Pharmaceutical Applications

Glycofurol is used as a solvent in parenteral products for intravenous or intramuscular injection in concentrations up to 50% v/v. It has also been investigated, mainly in animal studies, for use as a penetration enhancer and solvent in topical and intranasal formulations. Glycofurol has also been used at 20% v/v concentration in a rectal formulation.

Biological Activity

Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.

Safety

Glycofurol is mainly used as a solvent in parenteral pharmaceutical formulations and is generally regarded as a relatively nontoxic and nonirritant material at the levels used as a pharmaceutical excipient. Glycofurol can be irritant when used undiluted; its tolerability is approximately the same as propylene glycol.
Glycofurol may have an effect on liver function and may have a low potential for interaction with hepatoxins or those materials undergong extensive hepatic metabolism.
LD50 (mouse, IV): 3.5 mL/kg

storage

Stable if stored under nitrogen in a well-closed container protected from light, in a cool, dry place.

Incompatibilities

Incompatible with oxidizing agents.

Regulatory Status

Included in parenteral medicines licensed in Europe.

GLYCOFUROL Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 132)
Supplier Tel Email Country ProdList Advantage
Originchem Co., Ltd 0523-0523-86200346 15996028822 1583458435@qq.com China 79 58
Hubei Shishun Biotechnology Co. Ltd 027-59223025 15107168801 1718480011@qq.com China 9402 58
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Hubei Jusheng Technology Co.,Ltd 027-59599241 18871490274 1400878000@qq.com China 9506 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4189 55

View Latest Price from GLYCOFUROL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Glycofurol pictures 2026-09-15 Glycofurol
31692-85-0
1KG 95%-100% 10kg WUHAN FORTUNA CHEMICAL CO., LTD
GLYCOFUROL pictures 2026-09-15 GLYCOFUROL
31692-85-0
$75.00-100.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
GLYCOFUROL pictures 2026-08-20 GLYCOFUROL
31692-85-0
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
  • Glycofurol pictures
  • Glycofurol
    31692-85-0
  • 95%-100%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • GLYCOFUROL pictures
  • GLYCOFUROL
    31692-85-0
  • $75.00-100.00
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • GLYCOFUROL pictures
  • GLYCOFUROL
    31692-85-0
  • $1.10
  • 99.00%
  • Dideu Industries Group Limited
Glycols,polyethylene,mono(tetrahydrofurfuryl)ether tetrahydrofurfurylalkoholpolyaethylenglycolaether Tetraglycol,Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether TETRAHYDROFURFURYL POLYETHYLENE GLYCOL 200 TETRAHYDROFURFURYL ALCOHOL POLYETHYLENEGLYCOL ETHER Tetrahydrofurfuryl polyethylene glycol ether GLYCOFUROL GLYCOFUROL TETRAGLYCOL TETRAGLYCO Tetraglycol ( Glycofurol) TetrahydrofurfurylAlcoholPEGether Poly(oxy-1,2-ethanediyl), .alpha.-(tetrahydro-2-furanyl)methyl-.omega.-hydroxy- mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether 2-ethanediyl),alpha-[(tetrahydro-2-furanyl)methyl]-omega-hydroxy-Poly(oxy-1 alpha-((tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-2-ethanediyl) Glycofurol75 GLYCOFUROL-SPECIAL 2-(oxolan-2-ylmethoxy)ethanol Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether Tetrahydrofurfuryl polyethylene glycol 200, Mixture of diethylene and triethylene glycol mono-tetrahydrofurfuryl ether alpha-((Tetrahydro-2-furanyl)methyl)-omega-hydroxy-poly(oxy-1,2-E- thanediyl) Ethylene oxide homopolymer 2-tetrahydrofuranylmethyl ether Glycofurolum 75 TETRAHYDROFURFURYL ALCOHOL POLYETHYLENE GLYCOFUROL ISO 9001:2015 REACH Poly(oxy-1,2-ethanediyl),a-[(tetrahydro-2-furanyl)methyl]-w-hydroxy- Glycofurol extrapure, 99% Reaction products of tetrahydrofurfuryl alcohol with ethylene oxide GLYCOFUROL POLY(ETHYLENE GLYCOL) TETRAHYDROFURFURYL ETHER TETRAGLYCOL Glycofural THFP 31692-85-0 C2H4OnC5H10O2 HOCH2CH2O4H Biochemicals and Reagents BioChemical Carbohydrates Monosaccharide Heterobifunctional PEGs Materials Science Poly(ethylene glycol) and Poly(ethylene oxide) Polymer Science Polymers