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FM26

FM26 Structure
FM26 structure
CAS No.
2407981-35-3
Chemical Name:
FM26
Synonyms
FM26;FM26,FM-26;Benzoic acid, 4-[[[3-[2-chloro-6-(trifluoromethyl)phenyl]-5-(1H-pyrrol-3-yl)-4-isoxazolyl]methyl]amino]-
CBNumber:
CB78054406
Molecular Formula:
C22H15ClF3N3O3
Molecular Weight:
461.82
MDL Number:
MFCD34469875
MOL File:
2407981-35-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
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FM26 Properties

Boiling point 672.2±55.0 °C(Predicted)
Density 1.477±0.06 g/cm3(Predicted)
pka 4.63±0.10(Predicted)

FM26 Chemical Properties, Uses, Production

Description

FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.

Uses

FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1].

References

[1] Meijer FA, et al.Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists.J Med Chem. 2020 Jan 9;63(1):241-259. DOI:10.1021/acs.jmedchem.9b01372

FM26 Preparation Products And Raw materials

Raw materials

Preparation Products

FM26 Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from FM26 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FM26 pictures 2026-05-11 FM26
2407981-35-3
 $1970.00-3400.00 10g TargetMol Chemicals Inc.
FM26 pictures 2025-10-28 FM26
2407981-35-3
 $1970.00-3400.00 10g TargetMol Chemicals Inc.
  • FM26 pictures
  • FM26
    2407981-35-3
  • $1970.00-3400.00
  • TargetMol Chemicals Inc.
  • FM26 pictures
  • FM26
    2407981-35-3
  • $1970.00-3400.00
  • TargetMol Chemicals Inc.

2407981-35-3 (FM26) Related Search:

FM26 Cofetuzumab 1-Piperidinecarboxamide, 4-[3-[(2-chlorophenyl)methyl]-6,7-dihydro-7-oxo-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl]-N-[4-(trifluoromethyl)phenyl]- SR3335 ROR gamma-t-IN-1
SR 0987

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FM26 FM26,FM-26 Benzoic acid, 4-[[[3-[2-chloro-6-(trifluoromethyl)phenyl]-5-(1H-pyrrol-3-yl)-4-isoxazolyl]methyl]amino]- 2407981-35-3