Sodium picosulfate
- CAS No.
- 10040-45-6
- Chemical Name:
- Sodium picosulfate
- Synonyms
- Picosulfate Sodium;PICOSULPHATE SODIUM;Sodium picosulfate CRS;Sodium Picosulfate Hydrate;C13072;LA 391;DA-1773;DA 1773;Evacuol;Picolax
- CBNumber:
- CB7855531
- Molecular Formula:
- C18H13NO8S2.2Na
- Molecular Weight:
- 481.41
- MDL Number:
- MFCD00867640
- MOL File:
- 10040-45-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Picosulfate for system suitability European Pharmacopoeia (EP) Reference Standard | Y0001104 | 0.5 mg | $167 |
| Sodium picosulfate Pharmaceutical Secondary Standard; Certified Reference Material | PHR2540 | 100MG | $263 |
| Picosulfate for system suitability European Pharmacopoeia (EP) Reference Standard | Y0001104 | y0001104 | $153 |
| Picosulfate Sodium | 019705 | 10mg | $347 |
| Picosulfate Sodium | 019705 | 50mg | $453 |
| More product size | |||
| Melting point | 283-286°C |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Freely soluble in water, slightly soluble in ethanol 96 per cent. |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| Major Application |
pharmaceutical pharmaceutical small molecule |
| InChI | 1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2 |
| InChIKey | GOZDTZWAMGHLDY-UHFFFAOYSA-L |
| SMILES | C(C1N=CC=CC=1)(C1=CC=C(OS([O-])(=O)=O)C=C1)C1C=CC(OS([O-])(=O)=O)=CC=1.[Na+].[Na+] |
| FDA UNII | VW106606Y8 |
| ATC code | A06AB08,A06AB58 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H335-H319-H315 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| WGK Germany | WGK 3 |
| HS Code | 2933399090 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | mouse,LD50,intraperitoneal,2900mg/kg (2900mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATIONBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977. |
Sodium picosulfate price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001104 | Picosulfate for system suitability European Pharmacopoeia (EP) Reference Standard | 10040-45-6 | 0.5 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR2540 | Sodium picosulfate Pharmaceutical Secondary Standard; Certified Reference Material | 10040-45-6 | 100MG | $263 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001104 | Picosulfate for system suitability European Pharmacopoeia (EP) Reference Standard | 10040-45-6 | y0001104 | $153 | 2024-03-01 | Buy |
| Usbiological | 019705 | Picosulfate Sodium | 10040-45-6 | 10mg | $347 | 2026-06-03 | Buy |
| Usbiological | 019705 | Picosulfate Sodium | 10040-45-6 | 50mg | $453 | 2026-06-03 | Buy |
Sodium picosulfate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Originator
Guttalax, De Angelini, Italy ,1967
Uses
Sodium picosulfate acts as a stimulant laxative by increasing the frequency and the force of peristalsis and promoting electrolyte and water retention in the colon. Sodium picosulfate is most often used as laxatives.
Uses
Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
Definition
ChEBI: Sodium picosulfate is an aryl sulfate and a member of pyridines.
Therapeutic Function
Laxative
Side effects
Major minor side effects for Sodium Picosulfate:Diarrhoea, Abdominal pain, Nausea and vomiting, and Stomach cramps.
Synthesis
603-41-8
10040-45-6
The general procedure for the synthesis of (pyridin-2-ylmethylene)bis(4,1-phenylene)bis(sodium sulfate salt) from 4,4'-(pyridin-2-ylmethylene)bisphenol was as follows: the crude product of 4,4'-(pyridin-2-ylmethylene)bisphenol was dissolved in pyridine, and 39.5 g of chlorosulphonic acid was added slowly dropwise over the temperature range from 0 to 10°C. The reaction was carried out with continuous stirring. After the dropwise addition, the temperature was gradually increased to the reaction temperature and the reaction was continuously stirred for 1 hour. Subsequently, the reaction mixture was allowed to stir naturally at room temperature for 4 hours. Upon completion of the reaction, the reaction mixture was slowly poured into ice water and the pH was adjusted to 10 with 6 M sodium hydroxide solution. extraction was carried out with dichloromethane and the aqueous phase was separated and concentrated under reduced pressure. Finally, the product was collected by filtration and dried under vacuum at 40 °C to afford 34.8 g of sodium 4,4'-(pyridin-2-ylmethylene)diphenylsulfite, the product was a white solid with 99.8% purity and 86.4% yield.
References
[1] Patent: CN105175317, 2017, B. Location in patent: Paragraph 0054-0055; 0060
Sodium picosulfate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5214 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Lotusland Life Sciences | +8615821988213 | info@longyupharma.com | China | 2411 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hefei Hangang Pharmaceutical Technology Co., Ltd. | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8926 | 58 |
View Lastest Price from Sodium picosulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-05 | Sodium picosulfate
10040-45-6
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-09-04 | Sodium picosulfate
10040-45-6
|
1kg | 99.0% | 1000kg | Jinan Hong Kongda Chemical Co.,LTD | ||
 |
2026-09-04 | Sodium picosulfate
10040-45-6
|
1KG | 98.5%-100.5%; BP | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Sodium picosulfate
10040-45-6
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Sodium picosulfate
10040-45-6
- $0.00
- 99.0%
- Jinan Hong Kongda Chemical Co.,LTD
-
- Sodium picosulfate
10040-45-6
- $0.00
- 98.5%-100.5%; BP
- WUHAN FORTUNA CHEMICAL CO., LTD
