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8-Bromo-4-chromanone

CAS No.
204377-88-8
Chemical Name:
8-Bromo-4-chromanone
Synonyms
8-Bromo-4-chromanone;8-bromo-chroman-4-one;8-BroMo-4-chroManone 97%;8-broMo-2,3-dihydrochroMen-4-one;8-bromo-2,3-dihydro-4H-chromen-4-one;8-BROMO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE;8-broMo-3,4-dihydro-2H-1-benzopyran-4-one;8-Bromo-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-bromo-2,3-dihydro-
CBNumber:
CB7947485
Molecular Formula:
C9H7BrO2
Molecular Weight:
227.05
MDL Number:
MFCD09744046
MOL File:
204377-88-8.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46

8-Bromo-4-chromanone Properties

Boiling point 339℃
Density 1.621
Flash point 159℃
storage temp. Sealed in dry,Room Temperature
Appearance White to light yellow Solid

8-Bromo-4-chromanone price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix B61125 8-Bromochroman-4-one >98% 204377-88-8 1g $25 2026-05-06 Buy
Synthonix B61125 8-Bromochroman-4-one >98% 204377-88-8 5g $60 2026-05-06 Buy
aablocks AA0029CZ 8-Bromochroman-4-one 95% 204377-88-8 100mg $8 2026-05-28 Buy
aablocks AA0029CZ 8-Bromochroman-4-one 97% 204377-88-8 250mg $9 2026-05-28 Buy
aablocks AA0029CZ 8-Bromochroman-4-one 95% 204377-88-8 1g $12 2026-05-28 Buy
Product number Packaging Price Buy
B61125 1g $25 Buy
B61125 5g $60 Buy
AA0029CZ 100mg $8 Buy
AA0029CZ 250mg $9 Buy
AA0029CZ 1g $12 Buy

8-Bromo-4-chromanone Chemical Properties,Uses,Production

Uses

8-Bromo-4-dihydrochromone is an important intermediate, but its synthesis yield is low, it is difficult to synthesize, and its selling price is more than 20 times that of the similar product 6-bromo-3-dihydrochromone.

Synthesis

Benzene, 1-bromo-2-[(3-chloro-2-propyn-1-yl)oxy]-

1403387-58-5

8-Bromo-4-chromanone

204377-88-8

Step 3: Synthesis of 8-bromo-benzotetrahydropyran-4-one (P34c) Compound P34b (2.0 g, 8.15 mmol) was dissolved in ethylene glycol (20 mL) and heated to reflux for 4 hours. After completion of the reaction, the reaction mixture was cooled, poured into water and extracted twice with ether (Et2O). The organic layers were combined and washed sequentially with 1 M aqueous sodium hydroxide (NaOH) and saturated aqueous ammonium bicarbonate (NH4HCO3). The organic layers were dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated, and finally purified by column chromatography (eluent: petroleum ether/ethyl acetate = 50/1) to afford the target compound P34c (0.88 g, 48% yield) as a yellow solid.

References

[1] Patent: WO2012/139775, 2012, A1. Location in patent: Page/Page column 60-61

8-Bromo-4-chromanone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Litong Chemical Technology Co.,Ltd. 13598610367 0373-7129549 2468833170@qq.com China 932 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
SynAsst Chemical. 021-60343070 China 12731 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Zhengzhou ALFA Chemical Co., Ltd. 0371-53732842 15981811963 1758257485@qq.com China 949 56

View Lastest Price from 8-Bromo-4-chromanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-Bromochroman-4-one pictures 2026-09-11 8-Bromochroman-4-one
204377-88-8
$89.00-296.00 5g 0.99 25kg Shanghai UCHEM Inc.
8-Bromo-4-chromanone pictures 2022-01-04 8-Bromo-4-chromanone
204377-88-8
1g 98%minHPLC 50kgs/month Shanghai Rlavie Technology Co ltd
8-Bromo-4-chromanone pictures 2020-01-03 8-Bromo-4-chromanone
204377-88-8
$1.00 1KG 95-99% 1ton Career Henan Chemical Co
8-Bromo-4-chromanone 8-Bromo-2,3-dihydro-4H-1-benzopyran-4-one 8-broMo-3,4-dihydro-2H-1-benzopyran-4-one 8-BroMo-4-chroManone 97% 8-bromo-chroman-4-one 8-broMo-2,3-dihydrochroMen-4-one 8-bromo-2,3-dihydro-4H-chromen-4-one 8-BROMO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE 4H-1-Benzopyran-4-one, 8-bromo-2,3-dihydro- 204377-88-8