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6-Bromo-2,3-dihydro-4H-chromen-4-one

6-Bromo-2,3-dihydro-4H-chromen-4-one structure

CAS No.: 49660-57-3

Chemical Name:: 6-Bromo-2,3-dihydro-4H-chromen-4-one

Synonyms: 6-BROMOCHROMAN-4-ONE;EOS-60332;6-BROMOCHROMANONE;AKOS BBS-00006811;BUTTPARK 35\07-34;6-Bromo-4-chromone;6-Bromo-4-chromanone;6-BroMo-4-chroManone 97%;6-Bromochroman-4-one 98%;6-Bromo-4-chromanone≥ 98% (GC)

CBNumber:: CB2318893

Molecular Formula:: C9H7BrO2

Molecular Weight:: 227.05

MDL Number:: MFCD00546803

MOL File:: 49660-57-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:11:16

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6-Bromo-2,3-dihydro-4H-chromen-4-one Properties

Melting point	77-83°C
Boiling point	336.6±42.0 °C(Predicted)
Density	1.621±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
color	White to Orange to Green
InChI	InChI=1S/C9H7BrO2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5H,3-4H2
InChIKey	PFLPVOXSUCCZDH-UHFFFAOYSA-N
SMILES	C1OC2=CC=C(Br)C=C2C(=O)C1
CAS DataBase Reference	49660-57-3(CAS DataBase Reference)
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22
WGK Germany	3
HS Code	2914390090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral

6-Bromo-2,3-dihydro-4H-chromen-4-one price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	732788	6-Bromo-4-chromanone	49660-57-3	250mg	$130	2023-01-07	Buy
TCI Chemical	B5843	6-Bromo-4-chromanone >98.0%(GC)	49660-57-3	1g	$18	2026-04-30	Buy
TCI Chemical	B5843	6-Bromo-4-chromanone >98.0%(GC)	49660-57-3	5g	$70	2026-04-30	Buy
AK Scientific	AMTH345	6-Bromochroman-4-one 97%	49660-57-3	5g	$12	2026-06-04	Buy
AK Scientific	AMTH345	6-Bromochroman-4-one 97%	49660-57-3	25g	$20	2026-06-04	Buy

Product number	Packaging	Price	Buy
732788	250mg	$130	Buy
B5843	1g	$18	Buy
B5843	5g	$70	Buy
AMTH345	5g	$12	Buy
AMTH345	25g	$20	Buy

6-Bromo-2,3-dihydro-4H-chromen-4-one Chemical Properties,Uses,Production

Uses

4-Dihydrochromone is a class of natural compounds with excellent biological activities, including anticancer, antibacterial, anti-inflammatory, and anti-allergic activities, as well as antiplatelet aggregation activities. 6-Bromo-4-dihydrochromone is a derivative of 4-dihydrochromone and can be used as a pharmaceutical intermediate.

Chemical Properties

Pale yellow crystalline solid

Synthesis

93670-18-9

49660-57-3

3-(4-Bromophenoxy)propionic acid (150 g, 0.61 mol) was slowly added to 1.0 liter of concentrated sulfuric acid at room temperature with continuous stirring for 1 hour. Upon completion of the reaction, the mixture was carefully poured into 500 g of ice water, whereupon a white solid precipitated. The white solid was separated by filtration and dried naturally in air. The crude product was purified by recrystallization using ethanol, resulting in 89 g (64% yield) of the target compound 6-bromobenzodihydropyran-4-one as a white solid.

References

[1] E-Journal of Chemistry, 2012, vol. 9, # 3, p. 1251 - 1256
[2] Patent: CN106699716, 2017, A. Location in patent: Paragraph 0022; 0035
[3] Australian Journal of Chemistry, 2010, vol. 63, # 11, p. 1582 - 1593
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 4205,4207
[5] Tetrahedron, 2017, vol. 73, # 27-28, p. 3913 - 3922

6-Bromo-2,3-dihydro-4H-chromen-4-one Preparation Products And Raw materials

Raw materials

2-Oxetanone polyphosphoric acid Diethyl ether 4-Bromophenol 3-(4-Bromophenoxy)propanoic acid

4-Chromanone Water Sulfuric acid

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Preparation Products

6-Bromo-2,3-dihydro-4H-chromen-4-one Suppliers

Global( 231)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan EnTai Technology Development Co,.Ltd	86-27-82330560	2536851935@qq.com	China	346	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5681	66
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57

Supplier	Advantage
Wuhan EnTai Technology Development Co,.Ltd	69
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Accela ChemBio Co.,Ltd.	64
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
China DongFan Chemical Co.,LTD	66
Shandong Xiya Chemical Co., Ltd	57

View Lastest Price from 6-Bromo-2,3-dihydro-4H-chromen-4-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3	$20.00-367.00	25g	0.99	25kg	Shanghai UCHEM Inc.
2026-08-25	6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3	$2.20-8.80	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-08-20	6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

6-Bromo-2,3-dihydro-4H-chromen-4-one
49660-57-3
$20.00-367.00
0.99
Shanghai UCHEM Inc.

6-Bromo-2,3-dihydro-4H-chromen-4-one
49660-57-3
$2.20-8.80
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

6-Bromo-2,3-dihydro-4H-chromen-4-one
49660-57-3
$1.10
99.00%
Dideu Industries Group Limited

6-Bromo-2,3-dihydro-4H-chromen-4-one Spectrum

6-Bromo-2,3-dihydro-4H-chromen-4-one(49660-57-3)¹HNMR

49660-57-3(6-Bromo-2,3-dihydro-4H-chromen-4-one)Related Search:

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BUTTPARK 35\07-34 6-Bromochromanone (6-Bromochroman-4-one) 6-Bromo-2,3-dihydro-4H-chromen-4-one 6-Bromo-4-chromanone 6-broMo-3,4-dihydro-2H-1-benzopyran-2-one 6-BroMo-4-chroManone 97% 4H-1-BENZOPYRAN-4-ONE, 6-BROMO-2,3-DIHYDRO- 6-BROMOCHROMANONE 6-BROMO-2,3-DIHYDRO-4H-CHROMEN-4-ONE AKOS BBS-00006811 6-Bromo-4-chromanone 6-Bromo-4-chromanone≥ 98% (GC) 6-BroMo-2,3-dihydro-4H-1-benzopyran-4-one EOS-60332 6-Bromochroman-4-one 98% 6-Bromo-2,3-Dihydro-4H-Chromen-4-One,>98% 6-Bromo-4-chromone 6-Bromo-2,3-dihydro-4H-chromen-4-one ISO 9001：2015 REACH ethyl4-(4-methoxy-3-methylphenyl)-2,7-dioxobutanoate 6-Bromo-2,3-dihydro-4H-chromen-4-one 98% 6-BROMOCHROMAN-4-ONE 49660-57-3