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ChemicalBook >> CAS DataBase List >>5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Structure
5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester structure
CAS No.
885276-93-7
Chemical Name:
5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester
Synonyms
Ethyl 5-broMopyrazolo[1,5-a]pyridine-3-carboxylate;Ethyl 5-broMopyrazolo[1,5...;Ethyl 5-bromopyrazolo1,5-apyridin-3-carboxylate;ethyl 5-broMoH-pyrazolo[1,5-a]pyridine-3-carboxylate;5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylate ethyl ester;5-Bromopyrazolo[1,5-a]pyridin-3-carboxylic acid ethyl ester;5-bromo-3-pyrazolo[1,5-a]pyridinecarboxylic acid ethyl ester;5-BroMo-1H-pyrazolo[1,5-a]pyridin-3-carboxylic acid ethyl ester;Pyrazolo[1,5-a]pyridine-3-carboxylicacid, 5-bromo-, ethyl es...;Pyrazolo[1,5-a]pyridine-3-carboxylic acid, 5-broMo-, ethyl ester
CBNumber:
CB81501902
Molecular Formula:
C10H9BrN2O2
Molecular Weight:
269.09
MDL Number:
MFCD06739182
MOL File:
885276-93-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:18
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5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Properties

Density 1.60±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka -0.16±0.30(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C10H9BrN2O2/c1-2-15-10(14)8-6-12-13-4-3-7(11)5-9(8)13/h3-6H,2H2,1H3
InChIKey LJKZKCQPVABNLG-UHFFFAOYSA-N
SMILES C12=C(C(OCC)=O)C=NN1C=CC(Br)=C2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Chem-Impex 19100 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester ≥95% 885276-93-7 100MG $160.34 2026-05-19 Buy
Chem-Impex 19100 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester ≥95% 885276-93-7 250MG $259.99 2026-05-19 Buy
Chem-Impex 19100 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester ≥95% 885276-93-7 1G $536.71 2026-05-19 Buy
Chem-Impex 19100 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester ≥95% 885276-93-7 5G $1864.29 2026-05-19 Buy
Matrix Scientific 115388 Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate 885276-93-7 250.00mg $465 2026-05-18 Buy
Product number Packaging Price Buy
19100 100MG $160.34 Buy
19100 250MG $259.99 Buy
19100 1G $536.71 Buy
19100 5G $1864.29 Buy
115388 250.00mg $465 Buy

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Synthesis

1-Amino-4-bromopyridinium iodide

1533440-88-8

Ethyl propiolate

623-47-2

5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER

885276-93-7

General procedure for the synthesis of ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate from 1-amino-4-bromopyridinium iodide and ethyl propargylate: To a 250 mL three-necked round-bottomed flask was added 1-amino-4-bromopyridinium iodide (Compound 64.2, 15 g, ca. 50% purity, 24.9 mmol) in N,N-dimethylformamide (80 mL) Solution. Potassium carbonate (10.6 g, 76.7 mmol) was added batchwise, followed by ethyl propargylate (11.7 mL, 115 mmol) dropwise over 10 min. The reaction mixture was stirred overnight at room temperature and then diluted with ethyl acetate (300 mL) and water (100 mL). Insoluble solids were removed by filtration, and the organic layer was washed with saturated saline (3 x 50 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using ethyl acetate/petroleum ether (1:10) as eluent to afford ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate as a brown solid (300 mg, 6% yield).

References

[1] Patent: WO2014/8197, 2014, A1. Location in patent: Page/Page column 135
[2] Patent: WO2015/95767, 2015, A1. Location in patent: Page/Page column 150

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester synthesis

1533440-88-8
623-47-2
885276-93-7
Synthesis of 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester from 1-Amino-4-bromopyridinium iodide and Ethyl propiolate

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

1-Amino-4-bromopyridinium iodide Ethyl 2-(4-broMopyridin-2-yl)acetate ethyl 5-((tert-butoxycarbonyl)aMino)pyrazolo[1,5-a]pyridine-3-carboxylate 4-(Boc-amino)pyridine 4-Bromopyridine
Ethyl propiolate N,N-Dimethylformamide Potassium carbonate

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Preparation Products

5-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Suppliers

Global( 131)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Huiyu Biological Technology Co., LTD 17280940401 huiyu_bio@126.com China 1079 58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Jinan Kabotang Biological Technology Co.,Ltd. 0531-61320525 15866703830 figo.gao@foxmail.com China 7601 58
Shandong Boda Pharmaceutical Co., Ltd 18678253918 15624526479 18678253918@163.com China 39 58
Dalian Shuanghang Chemical Co., LTD +86-411-66858498 13941194417 sales@dl-bykj.cn China 1939 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7882 64
Supplier Advantage
Shanghai Huiyu Biological Technology Co., LTD 58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Jinan Kabotang Biological Technology Co.,Ltd. 58
Shandong Boda Pharmaceutical Co., Ltd 58
Dalian Shuanghang Chemical Co., LTD 58
Shanghai Boyle Chemical Co., Ltd. 55
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62
Tetranov Biopharm 64

View Lastest Price from 5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER pictures 2025-06-25 5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
885276-93-7
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
Ethyl 5-broMopyrazolo[1,5-a]pyridine-3-carboxylate pictures 2021-07-02 Ethyl 5-broMopyrazolo[1,5-a]pyridine-3-carboxylate
885276-93-7
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate pictures 2020-01-10 Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate
885276-93-7
 $1.00 1g 99% 200kg Career Henan Chemical Co

5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester Spectrum

5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER(885276-93-7)1HNMR

885276-93-7(5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester)Related Search:

5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester ETHYL 1,2,4-TRIAZINE-3-CARBOXYLATE Ethylenebis(nitrilodimethylene)tetraphosphonic acid ETHYL 5-BROMO-3-FORMYL-1H-INDOLE-2-CARBOXYLATE Ethyl5-bromo-1,3,4-thiadiazole-2-carboxylate
4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI) 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one 4,6-Dihydroxy-5-nitropyridine-3-carboxylic acid ethyl ester 8-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester
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2-CYANO-5-ETHOXYCARBONYLPYRIDINE 4,6-Dichloro-8-methylquinoline-3-carboxylic ethyl ester Methyl 6H-thieno[2,3-b]pyrrole-5-carboxylate

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5-Bromo-pyrazolo[1,5-a]pyridine-3-carboxylate ethyl ester Ethyl 5-broMopyrazolo[1,5... ethyl 5-broMoH-pyrazolo[1,5-a]pyridine-3-carboxylate 5-BroMo-1H-pyrazolo[1,5-a]pyridin-3-carboxylic acid ethyl ester Pyrazolo[1,5-a]pyridine-3-carboxylic acid, 5-broMo-, ethyl ester 5-Bromopyrazolo[1,5-a]pyridin-3-carboxylic acid ethyl ester 5-bromo-3-pyrazolo[1,5-a]pyridinecarboxylic acid ethyl ester 5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH Pyrazolo[1,5-a]pyridine-3-carboxylicacid, 5-bromo-, ethyl es... Pyrazolo[1,5-a]pyridine-3-carboxylic acid, 5-bromo-, ethyl ester (9CI, ACI) 5-bromo-Pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester (9CI ACI) Ethyl 5-bromopyrazolo1,5-apyridin-3-carboxylate Ethyl 5-broMopyrazolo[1,5-a]pyridine-3-carboxylate 885276-93-7 1363381-49-1 Heterocycle-Pyridine series