3-Bromo-4-fluoro-benzoic acid methyl ester
- CAS No.
- 82702-31-6
- Chemical Name:
- 3-Bromo-4-fluoro-benzoic acid methyl ester
- Synonyms
- METHYL 3-BROMO-4-FLUOROBENZOATE;RARECHEM AL BF 0277;Methyl 3-bromo-4-fluorobenzene;3-bromo-4-fluoro-2-methylbenzoate;Methyl3-bromo-4-fluorobenzoate98%;Methyl 3-bromo-4-fluorobenzoate 98%;3-Bromo-4-fluoro-benzoic acid methyl ester;Benzoic acid, 3-bromo-4-fluoro-, methyl ester
- CBNumber:
- CB8164036
- Molecular Formula:
- C8H6BrFO2
- Molecular Weight:
- 233.03
- MDL Number:
- MFCD04972915
- MOL File:
- 82702-31-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 26-28 |
|---|---|
| Boiling point | 245.3±20.0 °C(Predicted) |
| Density | 1.577±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to lump |
| color | White to Orange to Green |
| InChI | InChI=1S/C8H6BrFO2/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4H,1H3 |
| InChIKey | JVORYGNKYAXATM-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(F)C(Br)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Hazard Note | Irritant/Keep cold | |||||||||
| HS Code | 2916310090 | |||||||||
| NFPA 704 |
|
3-Bromo-4-fluoro-benzoic acid methyl ester price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M3018 | Methyl 3-Bromo-4-fluorobenzoate >98.0%(GC) | 82702-31-6 | 1g | $25 | 2026-04-30 | Buy |
| TCI Chemical | M3018 | Methyl 3-Bromo-4-fluorobenzoate >98.0%(GC) | 82702-31-6 | 5g | $82 | 2026-04-30 | Buy |
| Apolloscientific | PC1748 | Methyl 3-bromo-4-fluorobenzoate 98% | 82702-31-6 | 5g | $22 | 2026-06-04 | Buy |
| Apolloscientific | PC1748 | Methyl 3-bromo-4-fluorobenzoate 98% | 82702-31-6 | 25g | $94 | 2026-06-04 | Buy |
| Apolloscientific | PC1748 | Methyl 3-bromo-4-fluorobenzoate 98% | 82702-31-6 | 100g | $327 | 2026-06-04 | Buy |
3-Bromo-4-fluoro-benzoic acid methyl ester Chemical Properties, Uses, Production
Chemical Properties
off-white powder
Synthesis
67-56-1
1007-16-5
82702-31-6
a) Synthesis of methyl 3-bromo-4-fluorobenzoate 3-Bromo-4-fluorobenzoic acid (3.33 g, 15.2 mmol) was dissolved in methanol (30 mL) and acetyl chloride (4.3 mL, 60.8 mmol) was added slowly and dropwise under cooling in an ice bath. The reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the reaction solution was concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford methyl 3-bromo-4-fluorobenzoate (3.2 g, 90% yield) as a colorless oil.1H-NMR (CDCl3) δ: 3.92 (3H, s), 7.18 (1H, dd, J = 8.0, 8.2 Hz), 7.99 (1H, ddd, J = 1.9, 4.9, 8.0 Hz), 7.99 (1H, ddd, J = 1.9, 4.9, 8.0 Hz). 4.9, 8.0 Hz), 8.27 (1H, dd, J = 1.9, 6.5 Hz).
References
[1] European Journal of Medicinal Chemistry, 2007, vol. 42, # 11-12, p. 1334 - 1357
[2] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 16
[3] Journal of Enzyme Inhibition and Medicinal Chemistry, 2012, vol. 27, # 5, p. 658 - 665,8
[4] Patent: WO2007/99171, 2007, A2. Location in patent: Page/Page column 55
[5] ACS Medicinal Chemistry Letters, 2013, vol. 4, # 3, p. 358 - 362
3-Bromo-4-fluoro-benzoic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Baosheng Pharmaceutical Technology Co., Ltd., | 18616776591 | xuchenghao@sinch.com.cn | China | 265 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from 3-Bromo-4-fluoro-benzoic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | Methyl 3-bromo-4-fluorobenzoate
82702-31-6
|
5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Methyl 3-bromo-4-fluorobenzoate
82702-31-6
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
82702-31-6 (3-Bromo-4-fluoro-benzoic acid methyl ester) Related Search:
1of4
