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NAPROANILIDE

CAS No.
52570-16-8
Chemical Name:
NAPROANILIDE
Synonyms
mt101;MT-101;uribest;Urigbest;NAPROANILIDE;Naproanilide-D5;naproanilide (jmaf);Naproanilide,10ug/ml;NAPROANILIDE STANDARD;naproanilide (JMAF only)
CBNumber:
CB8180559
Molecular Formula:
C19H17NO2
Molecular Weight:
291.34
MDL Number:
MFCD01310442
MOL File:
52570-16-8.mol
MSDS File:
SDS
Last updated:2026-07-31 15:25:14
Product description Number Pack Size Price
Naproanilide CCA57016 5mg $873.25
Naproanilide CCA57016 10mg $1397.1
Naproanilide CCA57016 25mg $2278
Naproanilide CCA57016 50mg $3645
2-(2-NAPHTHYLOXY)PROPIONANILIDE 95.00% CHM0304535 5MG $503.45
More product size

NAPROANILIDE Properties

Melting point 128 °C
Boiling point 433.35°C (rough estimate)
Density 1.1552 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. 0-6°C
pka 13.46±0.70(Predicted)
Henry's Law Constant 1.6×105 mol/(m3Pa) at 25℃, Hilal et al. (2008)
EWG's Food Scores 1

NAPROANILIDE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CCA57016 Naproanilide 52570-16-8 5mg $873.25 2026-06-04 Buy
Biosynth CCA57016 Naproanilide 52570-16-8 10mg $1397.1 2026-06-04 Buy
Biosynth CCA57016 Naproanilide 52570-16-8 25mg $2278 2026-06-04 Buy
Biosynth CCA57016 Naproanilide 52570-16-8 50mg $3645 2026-06-04 Buy
American Custom Chemicals Corporation CHM0304535 2-(2-NAPHTHYLOXY)PROPIONANILIDE 95.00% 52570-16-8 5MG $503.45 2021-12-16 Buy
Product number Packaging Price Buy
CCA57016 5mg $873.25 Buy
CCA57016 10mg $1397.1 Buy
CCA57016 25mg $2278 Buy
CCA57016 50mg $3645 Buy
CHM0304535 5MG $503.45 Buy

NAPROANILIDE Chemical Properties,Uses,Production

Description

Naproanilide is a rice herbicide. Itself it has no herbicidal activity however its major metabolite 2-(2-naphthoxy)propionic acid does. It is only slightly toxic. Photodegradation appears to be the main degradation pathway in paddy fields. Little is known about the toxicity of this substance to wildlife.

Chemical Properties

Pure product is white crystal, odorless. m.p.128°C, relative density 1.256 (25°C), vapor pressure 66.66Pa (110°C). solubility at 27°C: acetone 171g/L, benzene 36g/L, toluene 42g/L, ethanol 17g/L, water 0.74mg/L. Stable in neutral and weakly acidic solution, unstable in alkaline or hot strongly acidic solution. The The original drug is stable to, but the drug solution is not stable after water. Half-life in soil is 2-7d, disappear in 1 month.

Uses

Naproanilide is used as a herbicide.

Definition

ChEBI: Naproanilide is a member of naphthalenes.

Production Methods

Naproanilide is synthesised through a three-step process starting from 2-chloropropanoic acid, aniline, and 2-naphthol. First, 2-chloropropanoic acid undergoes a nucleophilic substitution with aniline, where the amine group replaces the chlorine atom, forming an amide intermediate. In the second step, this intermediate reacts with 2-naphthol in the presence of a base, such as sodium hydroxide, which activates the phenolic oxygen to act as a nucleophile. This leads to the formation of a naphthyl ether linkage, completing the structure of naproanilide.

Mechanism of action

Stimulates RNA synthesis. Absorbed through stems and roots. No herbicidal activity itself but is rapidly hydrolysed to an active metabolite

Metabolic pathway

In the rice paddy ecosystem, naproanilide is biodegraded by the rice plant and organisms in the paddy field and by soil organisms and is mainly hydrolyzed to 2-(2-naphthoxy)propionic acid (NOP) and its methyl ester (NOPM). In rice plants (Oryza sativa L.) and Sagittaria pygmaea MIQ, naproanilide is metabolized to phytotoxic NOP. In rice plants, NOP subsequently undergoes hydroxylation and rapid conjugation with glucose. Phytotoxic NOP is produced only in a small amount. In S. pygmaea, the amounts of NOP and NOPM are significantly greater than those in rice plants. The difference in metabolites of naproanilide shows a possible mechanism of their herbicidal selectivity. Naproanilide and NOP in aqueous solution are rapidly degraded under sunlight and UV light. The disappearance of naproanilide in the paddy field is largely attributed to photochemical degradation in the surface water.

Pesticide Type

Herbicide

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
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Chongqing Chemdad Co., Ltd
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TianJin Alta Scientific Co., Ltd. 022-65378550-8551 contact@altascientific.com China 2772 58
Alta Scientific Co., Ltd. 022-6537-8550 15522853686 sales@altasci.com.cn China 4508 55
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Shandong Ono Chemical Co., Ltd. 0539-6362799 20) China 10007 58
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Shanghai Jiegu Biotechnology Co., Ltd. 021-51698675 sales@jiejiegroup.com China 8175 58
ShangHai Anpel Co, Ltd. 18502138905 shanpel@anpel.com.cn China 9604 58

View Lastest Price from NAPROANILIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
naproanilide (JMAF only) pictures 2020-02-13 naproanilide (JMAF only)
52570-16-8
$1.00 1KG Min98% HPLC Career Henan Chemical Co
2-(2-naphthalenyloxy)-n-phenyl-propanamid 2-(2-naphthalenyloxy)-n-phenylpropanamide 2-(2-naphthyloxy)propionanilide 2-(2-naphtyloxy) propionanilide [2S,(-)]-N-Phenyl-2-(2-naphthoxy)propionamide [S,(-)]-2-(2-Naphtyloxy)-N-phenylpropionamide [2R,(+)]-N-Phenyl-2-(2-naphthoxy)propionamide [R,(+)]-2-(2-Naphtyloxy)-N-phenylpropionamide 2-(2-Naphthyloxy)-N-phenylpropanamide 2-(2-Naphtyloxy)-N-phenylpropanamide N-Phenyl-2-(2-naphtyloxy)propionamide Propanamide, 2-(2-naphthalenyloxy)-N-phenyl- Naproanilide, 100 μg /μL in Acetone Naproanilide-D5 alpha-(2-naphthoxy)propionanilide alpha-(beta-naphthoxy)propionanilide mt101 MT-101 uribest NAPROANILIDE naproanilide (jmaf) Naproanilide,10ug/ml Urigbest NAPROANILIDE STANDARD naproanilide (JMAF only) Naproanilide@100 μg/mL in Acetone Naproanilide 10 μg/mL in Acetone 52570-16-8