5-Hydroxymethylthiophene-2-boronic acid
- CAS No.
- 338454-45-8
- Chemical Name:
- 5-Hydroxymethylthiophene-2-boronic acid
- Synonyms
- 5-HYDROXYMETHYLTHIOPHENE-2-BORONIC ACID;5-(hydroxymethyl)thiophen-2-yl]boronicaci;5-(Hydroxymethyl)thiophene-2-boronic aicd;[5-(hydroxyMethyl)thiophen-2-yl]boronic acid;5-(hydroxymethyl)thiophen-2-yl-2-boronic acid;5-Hydroxymethylthiophene-2-boronic acid, >=98%;Boronic acid, B-[5-(hydroxymethyl)-2-thienyl]-;(5-(Hydroxymethyl)thiophen-2-yl)boronic acid(contains varying amounts of Anhydride)
- CBNumber:
- CB8190815
- Molecular Formula:
- C5H7BO3S
- Molecular Weight:
- 157.98
- MDL Number:
- MFCD03095370
- MOL File:
- 338454-45-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2934999090 |
5-Hydroxymethylthiophene-2-boronic acid price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS15239 | 5-Hydroxymethylthiophene-2-boronic acid 97% | 338454-45-8 | 1g | $33 | 2026-06-04 | Buy |
| Activate Scientific | AS15239 | 5-Hydroxymethylthiophene-2-boronic acid 97% | 338454-45-8 | 5g | $144 | 2026-06-04 | Buy |
| Activate Scientific | AS15239 | 5-Hydroxymethylthiophene-2-boronic acid 97% | 338454-45-8 | 25g | $596 | 2026-06-04 | Buy |
| Synthonix | H41182 | (5-(Hydroxymethyl)thiophen-2-yl)boronic acid 97% | 338454-45-8 | 100mg | $15 | 2026-05-06 | Buy |
| Synthonix | H41182 | (5-(Hydroxymethyl)thiophen-2-yl)boronic acid 97% | 338454-45-8 | 250mg | $19 | 2026-05-06 | Buy |
5-Hydroxymethylthiophene-2-boronic acid Chemical Properties, Uses, Production
Synthesis
636-72-6
338454-45-8
General procedure for the synthesis of 5-hydroxymethylthiophene-2-boronic acid from 2-thiophene methanol: 2-hydroxymethylthiophene (2.28 g, 20 mmol) was dissolved in molecularly sieve-dried tetrahydrofuran (40 mL), the solution was cooled to -78 °C, and a 1.6 M n-butyllithium solution (25 mL, 40 mmol) in n-hexane was added slowly and dropwise, protected by argon gas. Subsequently, the reaction mixture was warmed to -30 °C and then cooled again to -78 °C and a solution of tetrahydrofuran (20 mL) of trimethyl borate (6.69 mL, 60 mmol) was added dropwise at this temperature. The reaction was held between -78 °C and -70 °C for 15 minutes. After continuing to stir at -78 °C for 2 h, the mixture was slowly warmed to room temperature and poured into water (50 mL) and the pH was adjusted to 3. 2 N aqueous hydrochloric acid (28 mL) was added and the mixture was extracted with ether, the extract was washed with saturated aqueous sodium chloride, dried over anhydrous sodium sulfate, filtered, and concentrated. The product 5-hydroxymethylthiophene-2-boronic acid 1.1 g (yield 36%) was obtained as a brown oil. Mass spectrum (MS): 158 (M).
References
[1] Patent: US6821980, 2004, B1. Location in patent: Page column 30-31
5-Hydroxymethylthiophene-2-boronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Nanjing Raise Pharmatech Co., Ltd. | 025-58649566 15005191108 | sales@njboyuanchem.com | China | 113 | 60 |
| Hebei Summedchem Co.,Ltd | 0319-5801333-8008 15630992918 | sales@summedchem.com | China | 1000 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai ShiXian Chemical Technology Co., Ltd. | 13764359345 | 990877971@qq.com | China | 1922 | 50 |
| Shanghai Aspire Biological Technology Co., Ltd. | 021-61317773 | sales@aspirebio.com | China | 2880 | 58 |
| Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd. | 19943855286 | 94644163@qq.com | China | 1934 | 56 |
View Latest Price from 5-Hydroxymethylthiophene-2-boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-20 | 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
|
1G | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2025-04-04 | 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2021-07-13 | 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
- $0.00
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Hydroxymethylthiophene-2-boronic acid
338454-45-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
