4-Perhydroazepinone hydrochloride
- CAS No.
- 50492-22-3
- Chemical Name:
- 4-Perhydroazepinone hydrochloride
- Synonyms
- 4-PerhydroazepinoneHCl;Azelastine Impurity 19;4-AZEPANONE HYDROCHLORIDE;4-Perhydroazepinone hydro;4-Azepanonehydrochloride,96%;HEXAHYDRO-4H-AZEPIN-4-ONE HCL;Azepan-4-one hydrochloride (1:1);4-PERHYDROAZEPINONE HYDROCHLORIDE;PERHYDROAZEPIN-4-ONEHYDROCHLORIDE;4-Oxohomopiperidine hydrochloride
- CBNumber:
- CB8202235
- Molecular Formula:
- C6H12ClNO
- Molecular Weight:
- 149.62
- MDL Number:
- MFCD02183487
- MOL File:
- 50492-22-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 176-181℃ |
|---|---|
| Flash point | 152°(306°F) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in DMSO, Ethanol, Methanol |
| form | Solid |
| color | White to Orange to Green |
| InChI | InChI=1S/C6H11NO.ClH/c8-6-2-1-4-7-5-3-6;/h7H,1-5H2;1H |
| InChIKey | WFTRLIZPJMFJER-UHFFFAOYSA-N |
| SMILES | C1(=O)CCNCCC1.Cl |
| CAS DataBase Reference | 50492-22-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H332-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-37/38-20/22 | |||||||||
| Safety Statements | 26-36/37/39-36/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2914290090 | |||||||||
| NFPA 704 |
|
4-Perhydroazepinone hydrochloride price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 737402 | Hexahydro-4-azepinone hydrochloride 96% | 50492-22-3 | 1g | $51.8 | 2026-04-30 | Buy |
| TCI Chemical | H1673 | Hexahydro-4-azepinone Hydrochloride | 50492-22-3 | 1G | $22 | 2026-04-30 | Buy |
| TCI Chemical | H1673 | Hexahydro-4-azepinone Hydrochloride | 50492-22-3 | 5G | $86 | 2026-04-30 | Buy |
| Biosynth | FA18073 | Azepan-4-one hydrochloride | 50492-22-3 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FA18073 | Azepan-4-one hydrochloride | 50492-22-3 | 2g | $150 | 2026-06-04 | Buy |
4-Perhydroazepinone hydrochloride Chemical Properties, Uses, Production
Chemical Properties
Yellow Solid
Uses
4-Azepanone hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
623-73-4
29976-53-2
50492-22-3
Step 1: Synthesis of azepan-4-one hydrochloride (intermediate): To a stirred solution of N-ethoxycarbonyl-4-piperidone (600 mg, 3.00 mmol) in anhydrous ether (1.5 mL) under nitrogen protection was added simultaneously a solution of boron trifluoride in ethyl ether (380 μL, 3.00 mmol) and ethyl diazoacetate (412 μL, 3.92 mmol) each dissolved in anhydrous ether (0.4 mL) to a solution at a reaction temperature of -35 °C. The reaction mixture was stirred continuously at -35 °C for 1 h 30 min, followed by slow warming to room temperature. After completion of the reaction, the reaction solution was washed with 30% aqueous potassium carbonate (3 mL) and the organic phase was extracted with ethyl acetate (3 x 5 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting crude product was dissolved in 4N aqueous hydrochloric acid (13 mL) and refluxed for 6 hours. At the end of the reaction, the solvent was removed under reduced pressure to give a light yellow oil (400 mg, 88% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 3.04 (m, 4H, CH2NH), 2.59 (m, 4H, CH2CO), 1.86 (m, 1H, NH), 1.75 (m, 2H, CH2CH2NH).
References
[1] Patent: EP1997381, 2008, A1. Location in patent: Page/Page column 16
[2] Patent: EP1997805, 2008, A1. Location in patent: Page/Page column 23
4-Perhydroazepinone hydrochloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Wenzhi Biotechnology Co., Ltd. | 13262848185 | 20840032@qq.com | China | 161 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Yangzhou Siyu Chemical Co.,Ltd. | 0514-87325867 | sales@siyuchem.com | China | 370 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from 4-Perhydroazepinone hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 4-Perhydroazepinone hydrochloride
50492-22-3
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
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2020-01-10 | 4-Perhydroazepinone hydrochloride
50492-22-3
|
$1.00 | 1g | 99.0% | 100kg | Career Henan Chemical Co |
-
- 4-Perhydroazepinone hydrochloride
50492-22-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-Perhydroazepinone hydrochloride
50492-22-3
- $1.00
- 99.0%
- Career Henan Chemical Co
