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Difluoxacin hydrochloride

CAS No.
91296-86-5
Chemical Name:
Difluoxacin hydrochloride
Synonyms
DIFLOXACIN HYDROCHLORIDE;DIFLOXACIN HCL;VETRANAL;6-FLUORO-1-(4-FLUOROPHENYL)-1,4-DIHYDRO-7-(4-METHYLPIPERAZINO)-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;Difluoxacin;Difluoxacin HCL;Difloxacin HCl - Bio-X ?;DIFLUOXACIN HYDROCHLORIDE;DifloxacinHydrochlorideSal;-7-(4-methylpiperazin-1-yl)
CBNumber:
CB8208196
Molecular Formula:
C21H20ClF2N3O3
Molecular Weight:
435.85
MDL Number:
MFCD03840489
MOL File:
91296-86-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

Difluoxacin hydrochloride Properties

Melting point >245°C (dec.)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in aqueous buffer
form powder
color White to off-white
Major Application forensics and toxicology
pharmaceutical (small molecule)
InChI InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H
InChIKey JFMGBGLSDVIOHL-UHFFFAOYSA-N
SMILES C12C=C(C(F)=CC=1C(C(C(=O)O)=CN2C1=CC=C(F)C=C1)=O)N1CCN(C)CC1.Cl
CAS DataBase Reference 91296-86-5(CAS DataBase Reference)
FDA UNII XJ0260HJ0O
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
RTECS  VB2008975
Storage Class 11 - Combustible Solids

Difluoxacin hydrochloride price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001423 Difloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard 91296-86-5 60 mg $167 2026-04-30 Buy
Sigma-Aldrich 33984 Difloxacin hydrochloride VETRANAL?, analytical standard 91296-86-5 100mg $75.9 2026-04-30 Buy
Cayman Chemical 29000 Difloxacin (hydrochloride) ≥98% 91296-86-5 1mg $36 2026-04-30 Buy
Cayman Chemical 29000 Difloxacin (hydrochloride) ≥98% 91296-86-5 5mg $160 2026-04-30 Buy
Cayman Chemical 29000 Difloxacin (hydrochloride) ≥98% 91296-86-5 25mg $303 2026-04-30 Buy
Product number Packaging Price Buy
Y0001423 60 mg $167 Buy
33984 100mg $75.9 Buy
29000 1mg $36 Buy
29000 5mg $160 Buy
29000 25mg $303 Buy

Difluoxacin hydrochloride Chemical Properties, Uses, Production

Brand Name(s) in US

Dicural

Description

Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

antibacterial, DNA gyrase inhibitor

Uses

A quinolone antibacterial compound. Structurally related to norfloxacin

Uses

A fluoroquinolone antibacterial structurally related to norfloxacin.

References

[1] M B BANSAL  H T. Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1987, 31 4: 619-621. DOI: 10.1128/aac.31.4.619
[2] H THADEPALLI  S K C  S V Gollapudi. Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscess.[J]. Antimicrobial Agents and Chemotherapy, 1986, 30 4: 574-576. DOI: 10.1128/aac.30.4.574

Difluoxacin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 218)
Supplier Tel Email Country ProdList Advantage
Shanghai Gukang Biotechnology Co., LTD 13564510648 2985380065@qq.com China 111 58
Kaifeng Mingren Pharmaceutical Co.,LTD 13503833127 zhanghuiyuan@shmathcon.com China 39 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58

View Latest Price from Difluoxacin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Difloxacin Hydrochloride pictures 2026-09-01 Difloxacin Hydrochloride
91296-86-5
1kg 99% 1000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Difluoxacin hydrochloride pictures 2026-08-25 Difluoxacin hydrochloride
91296-86-5
1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
Difluoxacin hydrochloride USP/EP/BP pictures 2026-08-20 Difluoxacin hydrochloride USP/EP/BP
91296-86-5
$1.10 1g 99.9% 100 Tons Min Dideu Industries Group Limited

Difluoxacin hydrochloride Spectrum

DIFLUOXACIN HYDROCHLORIDE Difluoxacin HCL 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid hydrochloride 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monohydrochloride -4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 6-Fluoro-1-(4-fluorophenyl) -7-(4-methylpiperazin-1-yl) Double difloxacin hydrochloride Difloxacin hydrochloride Solution, 1000ppm 6-fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid The effect of hydrochloric acid two fluorine Difluoxacin Difloxacin hydrochloride CRS 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride DifloxacinHydrochlorideSal Difluoxacin hydrochloride USP/EP/BP C12627000 Difloxacin hydrochloride Difloxacin HCl - Bio-X ? Difluoroxacin hydrochloride Difloxacin hydrochloride (Standard) 6-FLUORO-1-(4-FLUOROPHENYL)-1,4-DIHYDRO-7-(4-METHYLPIPERAZINO)-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE DIFLOXACIN HCL DIFLOXACIN HYDROCHLORIDE VETRANAL 91296-86-5 C21H19F2N3O3HCl C21H19F2N3O3ClH DICURAL Active Pharmaceutical Ingredients Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals API