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Difloxacin

CAS No.
98106-17-3
Chemical Name:
Difloxacin
Synonyms
a56619;DIFLOXACIN;Difloxacin USP/EP/BP;-1-piperazinyl)-4-oxo-;DIFLOXACINHCL/MESYLATE;Acrylamide Impurity 32;Difloxacin in Methanol/DMSO;Difloxacin Hydrochloride Salt;3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl;6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci
CBNumber:
CB5175282
Molecular Formula:
C21H19F2N3O3
Molecular Weight:
399.39
MDL Number:
MFCD00865975
MOL File:
98106-17-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:04:38
Product description Number Pack Size Price
6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% AA00IJYE 10mg $54
6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% AA00IJYE 100mg $220
Difloxacin 95+% CD31000029 1g $277
6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% CM126792 1g $259
Difloxacin 97% MT-50135 100g $680
More product size

Difloxacin Properties

Melting point 279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
Boiling point 595.5±50.0 °C(Predicted)
Density 1.409±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 6.17±0.41(Predicted)
color White to Pale Yellow
CAS DataBase Reference 98106-17-3(CAS DataBase Reference)
FDA UNII 5Z7OO9FNFD

SAFETY

Risk and Safety Statements

Difloxacin price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00IJYE 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% 98106-17-3 10mg $54 2026-05-29 Buy
aablocks AA00IJYE 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% 98106-17-3 100mg $220 2026-05-29 Buy
Crysdot CD31000029 Difloxacin 95+% 98106-17-3 1g $277 2026-05-27 Buy
Chemenu CM126792 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% 98106-17-3 1g $259 2026-05-26 Buy
AHH MT-50135 Difloxacin 97% 100g $680 2026-05-26 Buy
Product number Packaging Price Buy
AA00IJYE 10mg $54 Buy
AA00IJYE 100mg $220 Buy
CD31000029 1g $277 Buy
CM126792 1g $259 Buy
MT-50135 100g $680 Buy

Difloxacin Chemical Properties,Uses,Production

Description

Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin.

Mechanism of action

Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. 

Physical properties

Whtie-Cream to Yellowish Crystalline Powder

Uses

Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin.

Definition

ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall as the monohydrochloride salt) for the treatment of bacterial infections in dogs.

704-10-9
98106-17-3
Synthesis of Difloxacin from 2,4-Dichloro-5-fluoroacetophenone

Difloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
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Career Henan Chemica Co
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Dideu Industries Group Limited
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AFINE CHEMICALS LIMITED
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Finetech Industry Limited
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Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39037 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20120 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19956 58

View Lastest Price from Difloxacin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Difloxacin HCl pictures 2026-05-11 Difloxacin HCl
98106-17-3
$1520.00-2500.00 10g TargetMol Chemicals Inc.
Difloxacin USP/EP/BP pictures 2025-11-18 Difloxacin USP/EP/BP
98106-17-3
$1.10 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Difloxacin HCl pictures 2025-07-20 Difloxacin HCl
98106-17-3
$1520.00-2500.00 10g TargetMol Chemicals Inc.
DIFLOXACIN -1-piperazinyl)-4-oxo- 3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl a56619 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt Difloxacin Hydrochloride Salt 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid DIFLOXACINHCL/MESYLATE 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid 6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic ac 6-Fluoro-1-(4-fluorophenyl)-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo- 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci Difloxacin USP/EP/BP Difloxacin in Methanol/DMSO Acrylamide Impurity 32 98106-17-3 C21H20ClF2N3O3 C21H19F2N3O3 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents