SILTHIOFAM
- CAS No.
- 175217-20-6
- Chemical Name:
- SILTHIOFAM
- Synonyms
- MON65500;LATITUDE;SILTHIOFAM;Silthiopham;Silthiofarm;silthiofam 98%;Silthiofam [iso];silthiofam (bsi,iso);C16947000 Silthiofam;Silthiofam (Standard)
- CBNumber:
- CB8213578
- Molecular Formula:
- C13H21NOSSi
- Molecular Weight:
- 267.46
- MDL Number:
- MFCD04112621
- MOL File:
- 175217-20-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Silthiofam PESTANAL | 32498 | 25mg | $232 |
| Silthiofam | AHA21720 | 5mg | $242 |
| Silthiofam | AHA21720 | 10mg | $378.1 |
| Silthiofam | AHA21720 | 25mg | $756.25 |
| Silthiofam | AHA21720 | 50mg | $1361.5 |
| More product size | |||
| Boiling point | 303.2±42.0 °C(Predicted) |
|---|---|
| Density | 1.01±0.1 g/cm3(Predicted) |
| Flash point | 12°C |
| pka | 15.11±0.46(Predicted) |
| Henry's Law Constant | 1.9×100 mol/(m3Pa) at 25℃, Maniere et al. (2011) |
| Major Application |
agriculture environmental |
| InChI | 1S/C13H21NOSSi/c1-7-8-14-12(15)11-9(2)10(3)16-13(11)17(4,5)6/h7H,1,8H2,2-6H3,(H,14,15) |
| InChIKey | MXMXHPPIGKYTAR-UHFFFAOYSA-N |
| SMILES | Cc1sc(c(c1C)C(=O)NCC=C)[Si](C)(C)C |
| FDA UNII | 5991I541GW |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H373-H411 |
| Precautionary statements | P260-P273-P314-P391-P501 |
| Risk Statements | 52/53 |
| Safety Statements | 61 |
| RIDADR | UN1219 - class 3 - PG 2 - Isopropanol |
| WGK Germany | 1 |
| RTECS | NT8050000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 2 STOT RE 2 |
SILTHIOFAM price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 32498 | Silthiofam PESTANAL | 175217-20-6 | 25mg | $232 | 2026-04-30 | Buy |
| Biosynth | AHA21720 | Silthiofam | 175217-20-6 | 5mg | $242 | 2026-06-04 | Buy |
| Biosynth | AHA21720 | Silthiofam | 175217-20-6 | 10mg | $378.1 | 2026-06-04 | Buy |
| Biosynth | AHA21720 | Silthiofam | 175217-20-6 | 25mg | $756.25 | 2026-06-04 | Buy |
| Biosynth | AHA21720 | Silthiofam | 175217-20-6 | 50mg | $1361.5 | 2026-06-04 | Buy |
SILTHIOFAM Chemical Properties,Uses,Production
Chemical Properties
Silithiamide is white granular solid, melting point is 86.1~88.3℃, vapor pressure(20℃)8.1×10mPa. kow lgP=3.72(20℃), Henry's constant 5.4×10-1 Pa -m3/ mol, relative density 1.07(20℃). Solubility in water (20°C) 39.9 mg/L. Solubility in organic solvents (20°C, g/L): n-heptane 15.5, xylene, 1,2-dichloromethane, methanol, acetone, and ethyl acetate were all greater than 250. Stability DT50 (25°C): 6ld (pH 5), 448d (pH 7), 314d (pH 9).
Uses
Silthiofam is a fungicide. It is derived from 3-Chloro-2-butanone (C366895), which is widely used in the chemical and pharmaceutical industries as an intermediate or starting material (for example its use in a one-pot synthesis of γ-iminolactones). Also, it is derived from 2-Amino-4,5-dimethyl-3-thiophenecarboxylic Acid Ethyl Ester (A605165), which is used in the preparation triazine and pyrimidine derivatives as anti-inflammatory and analgesic agents. Also used in the synthesis of antioxidants through heteroaryl amines as well as CB2 cannabinoid receptor partial agonists.
Definition
ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group from 4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxlic acid with the amino group of allylamine. A fungicide seed dressing for cereals used mainly to control 'take-all'.
Mechanism of action
Protective action with long-lasting activity. Respiration inhibitor - ATR production.
Synthesis
Silthiofam is synthesized in three steps. 1) Preparation of methyl trimethylsilylpropynoate: Trimethylsilylacetylene reacts with n-butyllithium, then with methyl chloroformate. Work-up and purification yield the product. 2) Preparation of methyl 4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxylate: The product from step 1 reacts with 3-mercapto-2-butanone in toluene with sodium methoxide under reflux. Work-up and purification give the product. 3) Preparation of the final product: The ester from step 2 reacts with excess allylamine catalyzed by TBD under heating and reflux. Work-up yields silthiofam.
Pesticide Type
Fungicide
SILTHIOFAM Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao Trust Agri Chemical Co.,Ltd | +86-008615963231493 +86-008613573296305 | trustagri@hotmail.com | China | 298 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4011 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +86-15195660023 | 3899766280@qq.com | China | 26349 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 | sales@anikare.com | China | 9993 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Shaanxi Dideu New Materials Co. Ltd | 18192503167 | 1036@dideu.com | China | 13149 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Lastest Price from SILTHIOFAM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | silthiopham
175217-20-6
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-06-30 | SILTHIOFAM
175217-20-6
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-21 | Silthiofam
175217-20-6
|
$1660.00-2790.00 | 10g | TargetMol Chemicals Inc. |
-
- silthiopham
175217-20-6
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-
- SILTHIOFAM
175217-20-6
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
- Silthiofam
175217-20-6
- $1660.00-2790.00
- TargetMol Chemicals Inc.
