ChemicalBook >> CAS DataBase List >>3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride
3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride
- CAS No.
- 63286-28-2
- Chemical Name:
- 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride
- Synonyms
- 2-chloro-3-hydrazineylpyrazine;oro-3-hydrazinyL;2-Chloro-3-hydrazinopyrazine;2-CHLORO-3-HYDRAZINYLPYRAZINE;(3-Chloropyrazin-2-yl)hydrazine;Pyrazine,2-chloro-3-hydrazinyl-;2-(3-chloropyrazin-2-yl)hydrazine;3-Chloro-2(H)-pyrazinone hydrazone;2-Chloro-3-hydrazinopyrazine, 97%min;2-chloro-3-hydrazinopyrazine(SALTDATA: FREE)
- CBNumber:
- CB8221810
- Molecular Formula:
- C4H5ClN4
- Molecular Weight:
- 144.56
- MDL Number:
- MFCD08272804
- MOL File:
- 63286-28-2.mol
- MSDS File:
- SDS
Last updated:2026-09-12 18:55:31
| Melting point | 154-159°C |
|---|---|
| Boiling point | 271.0±23.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 1.27±0.20(Predicted) |
| color | Very Dark Red to Brown |
| InChI | 1S/C4H5ClN4/c5-3-4(9-6)8-2-1-7-3/h1-2H,6H2,(H,8,9) |
| InChIKey | PUUGNIKJWZNTBK-UHFFFAOYSA-N |
| SMILES | NNc1nccnc1Cl |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H318-H335 |
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338+P310 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-39 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| HS Code | 2933998090 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
| Limited Quantities | 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 738964 | 2-Chloro-3-hydrazinopyrazine 95% | 63286-28-2 | 1g | $72.5 | 2026-04-30 | Buy |
| Usbiological | 270062 | 3-Chloro-2-Hydrazino-1,2-Dihydropyrazine Hydrochloride Asreported | 63286-28-2 | 250mg | $375 | 2026-06-03 | Buy |
| Usbiological | 270062 | 3-Chloro-2-Hydrazino-1,2-Dihydropyrazine Hydrochloride Asreported | 63286-28-2 | 500mg | $523 | 2026-06-03 | Buy |
| Usbiological | 270062 | 3-Chloro-2-Hydrazino-1,2-Dihydropyrazine Hydrochloride Asreported | 63286-28-2 | 1g | $781 | 2026-06-03 | Buy |
| Usbiological | 270062 | 3-Chloro-2-Hydrazino-1,2-Dihydropyrazine Hydrochloride Asreported | 63286-28-2 | 2g | $1087 | 2026-06-03 | Buy |
3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Chemical Properties, Uses, Production
Synthesis
4858-85-9
63286-28-2
Step 1: 2,3-Dichloropyrazine (150 g, 1.00 mol) was dissolved in ethanol (700 mL) to which hydrazine monohydrate (124.53 g, 2.11 mmol, 85% aqueous solution) was subsequently added. The reaction mixture was heated under reflux conditions overnight. Upon completion of the reaction, the mixture was cooled and the precipitate was collected by filtration. The resulting solid was washed sequentially with water (100 mL, twice) and cold ethanol (150 mL, twice) and finally dried under reduced pressure to give 2-chloro-3-hydrazinopyrazine (140 g, 96% yield).
References
[1] Patent: WO2016/55618, 2016, A1. Location in patent: Page/Page column 64
[2] Patent: US2014/142098, 2014, A1. Location in patent: Paragraph 0233 - 0236
[3] Patent: US2015/133447, 2015, A1. Location in patent: Paragraph 0287; 0288; 0289
[4] Patent: WO2013/39785, 2013, A2. Location in patent: Page/Page column 80; 81
[5] Patent: WO2008/130951, 2008, A1. Location in patent: Page/Page column 60
3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Preparation Products And Raw materials
3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Suppliers
Global Suppliers ( 105)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Shanghai Xiannuo Biotechnology Co., Ltd. | 021-50718719 13918719472 | China | 978 | 58 | |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
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