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8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt structure

CAS No.: 153660-04-9

Chemical Name:: 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt

Synonyms: RP-8-PCPT-CGMPS;RP-8-PCPT-CGMPS, TEA;8 PCPT-CGMPS NA, RP-ISOMER;RP-8-PCPT-CGMPS SODIUM SALT;8 PCPT-CGMPS TEA, RP-ISOMER;Rp-8-pCPT-cyclic GMPS Sodium;RP-8-P-CPT-CGMPS TRIETHYLAMINE;RP-8-[(4-CHLOROPHENYL)THIO]-CGMPS TRIETHYLAMINE;rp-8-[(4-chlorophenyl)thio]-cgmps triethylammonium salt;Guanosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[hydrogen (R)-phosphorothioate]

CBNumber:: CB8225146

Molecular Formula:: C16H15ClN5O6PS2

Molecular Weight:: 503.88

MDL Number:: MFCD01861936

MOL File:: 153660-04-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:55:31

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8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt Properties

storage temp.	−20°C
solubility	H₂O: 5 mg/mL
form	solid
color	white
Water Solubility	water: 0.5mg/mL DMSO: soluble
UNSPSC Code	41106305
NACRES	NA.77

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	370677	Guanosine 3′,5′-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, a		1 μmol	$352	2025-07-31	Buy
Sigma-Aldrich	370677	Guanosine 3′,5′-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.		1μMOL	$403	2024-03-01	Buy
American Custom Chemicals Corporation	NUC0003400	8-(4-CHLOROPHENYLTHIO)GUANOSINE-3',5'-CYCLIC MONOPHOSPHOTHIOATE-RP-ISOMER SODIUM SALT 95.00%	153660-04-9	5MG	$504.39	2021-12-16	Buy

Product number	Packaging	Price	Buy
370677	1 μmol	$352	Buy
370677	1μMOL	$403	Buy
NUC0003400	5MG	$504.39	Buy

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt Chemical Properties, Uses, Production

Uses

Rp-8-pCPT-cGMPS is a competitive inhibitor of cGMP-dependent protein kinase (PKG) (Ki=0.5 μM). Rp-8-pCPT-cGMPS has high lipid solubility and can more easily penetrate the cell membrane and reach sufficient concentration inside the cell to inhibit cGMP-dependent protein kinase. Rp-8-pCPT-cGMPS can be used to study the activity and function of cGMP-dependent protein kinase in platelets[1].

Biological Activity

Cell permeable: yes', 'Primary Target
PKG1α', 'Product does not compete with ATP.', 'Reversible: no

References

[1] E Butt, et al. (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. European Journal of Pharmacology: Molecular Pharmacology 269.2 (1994): 265-268. DOI:10.1016/0922-4106(94)90095-7

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt Preparation Products And Raw materials

Raw materials

Preparation Products

8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt Suppliers

Global Suppliers ( 18)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
BOC Sciences	16314854226	inquiry@bocsci.com	United States	9713	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Shanghai meikai technology co., ltd	021-68689288 15300790979	info@mkbio.com.cn	China	9988	58

Supplier	Advantage
Shanghai EFE Biological Technology Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Shanghai meikai technology co., ltd	58

153660-04-9 (8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt) Related Search:

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RP-8-[(4-CHLOROPHENYL)THIO]-GUANOSINE-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE TRIETHYLAMINE RP-8-PCPT-CGMPS RP-8-PCPT-CGMPS SODIUM SALT RP-8-PCPT-CGMPS, TEA RP-8-P-CPT-CGMPS TRIETHYLAMINE 8-(4-CHLOROPHENYLTHIO) GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 8-(4-CHLOROPHENYLTHIO)GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE SODIUM SALT, RP-ISOMER 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER SODIUM SALT 8 PCPT-CGMPS TEA, RP-ISOMER 8 PCPT-CGMPS NA, RP-ISOMER GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-(4-CHLOROPHENYLTHIO)-, RP-ISOMER, TRIETHYLAMMONIUM SALT 8-(4-chlorophenylthio)-guanosine 3',5'-cyclic monophosphorothioate, rp isomer triethylammonium salt rp-8-[(4-chlorophenyl)thio]-cgmps triethylammonium salt Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt, Rp-8-CPT-cGMPS, Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3μ,5μ-hydrogen phosphorothioate triethylammonium salt Rp-8-pCPT-cyclic GMPS Sodium RP-8-[(4-CHLOROPHENYL)THIO]-CGMPS TRIETHYLAMINE RP-8-[(4-CHLOROPHENYL)THIO]-GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE 8-(4-chlorophenylthio)guanosine-3’,5’-cyclicmonophosphorothioate,rp-isomer(rp-8-pcpt-cgmps),sod Guanosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[hydrogen (R)-phosphorothioate] (2R,3R,4S,5R)-2-{2-amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt 153660-04-9 C16H15ClN5O6PS2C6H15N BioChemical Cell Biology Cell Signaling and Neuroscience G Proteins and Cyclic Nucleotides Cyclic Nucleotide Metabolism Cyclic Nucleotides and Analogs