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8-MERCAPTOGUANOSINE

8-MERCAPTOGUANOSINE structure

CAS No.: 26001-38-7

Chemical Name:: 8-MERCAPTOGUANOSINE

Synonyms: 8-SH-Guo;Nsc79216;SQ 12760;8-Tio-Guanosine;8-THIOGUANOSINE;8-MERCAPTOGUANOSINE;8-MERCAPTOGUANOSINE HYDRATE;7,8-dihydro-8-thioxoguanosine;8-Mercapto-7,8-dihydroguanosin;Guanosine, 7,8-dihydro-8-thioxo-

CBNumber:: CB9347935

Molecular Formula:: C10H13N5O5S

Molecular Weight:: 315.31

MDL Number:: MFCD00057038

MOL File:: 26001-38-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:28:43

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8-MERCAPTOGUANOSINE Properties

Melting point	>220 °C
Density	2.35±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly)
pka	6.15±0.20(Predicted)
form	crystalline
color	light yellow
Stability	Hygroscopic
FDA UNII	B0T9FOW56N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
WGK Germany	3
HS Code	29389090

8-MERCAPTOGUANOSINE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	296467	8-Thioguanosine Asreported	26001-38-7	5mg	$340	2026-06-03	Buy
Usbiological	296467	8-Thioguanosine Asreported	26001-38-7	10mg	$475	2026-06-03	Buy
Usbiological	296467	8-Thioguanosine Asreported	26001-38-7	25mg	$658	2026-06-03	Buy
Usbiological	296467	8-Thioguanosine Asreported	26001-38-7	50mg	$885	2026-06-03	Buy
Usbiological	296467	8-Thioguanosine Asreported	26001-38-7	100mg	$1238	2026-06-03	Buy

Product number	Packaging	Price	Buy
296467	5mg	$340	Buy
296467	10mg	$475	Buy
296467	25mg	$658	Buy
296467	50mg	$885	Buy
296467	100mg	$1238	Buy

8-MERCAPTOGUANOSINE Chemical Properties, Uses, Production

Chemical Properties

Light yellow fine crystalline powder

Uses

8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll[1][2].

References

[1] Mond JJ, Hunter K, Kenny JJ, Finkelman F, Witherspoon K. 8-Mercaptoguanosine-mediated enhancement of in vivo IgG1, IgG2 and IgG3 antibody responses to polysaccharide antigens in normal and xid mice. Immunopharmacology. 1989 Nov-Dec;18(3):205-12. DOI:10.1016/0162-3109(89)90018-0
[2] Feldbush TL, Ballas ZK. Lymphokine-like activity of 8-mercaptoguanosine: induction of T and B cell differentiation. J Immunol. 1985 May;134(5):3204-11. PMID:3872330

8-MERCAPTOGUANOSINE synthesis

Synthesis of 8-MERCAPTOGUANOSINE from 8-Bromoguanosine

8-MERCAPTOGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

8-Aminoguanosine Guanosine

8-MERCAPTOGUANOSINE Suppliers

Global Suppliers ( 63)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
UHN Shanghai Research & Development Co., Ltd.	021-58958002 18930822973	sales@uhnshanghai.com	China	997	58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd.	0371-85513397	info@granlen.com	China	497	55
Wuhu Nuowei Chemical Technology Co., Ltd	0553-8233716 18055326116	sales@nuowei-chem.com	China	742	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-58851090 13913916777	sales01@aikonchem.com	China	15947	58
Fuyang Ziyi Biological Pharmaceutical Co., Ltd.	19308655899; 19308655899	2677609105@qq.com	China	500	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
Finetech Industry Limited	+86-27-8746-5837 +86-18627785180	info@finetechnology-ind.com	China	9533	58
NewCan Biotech Limited	+86-571-86912261 19975279805	sales@newcanbio.com	China	9984	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
UHN Shanghai Research & Development Co., Ltd.	58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd.	55
Wuhu Nuowei Chemical Technology Co., Ltd	55
Amadis Chemical Company Limited	58
Aikon International Limited	58
Fuyang Ziyi Biological Pharmaceutical Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Finetech Industry Limited	58
NewCan Biotech Limited	58

View Latest Price from 8-MERCAPTOGUANOSINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-13	8-MERCAPTOGUANOSINE 26001-38-7		1G	97%	2000	Shenzhen Nexcon Pharmatechs Ltd.
	2025-04-04	8-MERCAPTOGUANOSINE 26001-38-7		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

8-MERCAPTOGUANOSINE
26001-38-7
97%
Shenzhen Nexcon Pharmatechs Ltd.

8-MERCAPTOGUANOSINE
26001-38-7
98%
Henan Aochuang Chemical Co.,Ltd.

8-MERCAPTOGUANOSINE Spectrum

8-MERCAPTOGUANOSINE(26001-38-7)¹HNMR

26001-38-7 (8-MERCAPTOGUANOSINE) Related Search:

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8-(2-AMINOETHYL) THIOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE, IMMOBILIZED ON AGAROSE GEL 2'-deoxy-6-thioguanosine 5'-triphosphate 8-(2-AMINOETHYL) THIOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER, IMMOBILIZED ON AGAROSE GEL 8-(2-Aminoethylthio) guanosine-3',5'-cyclic monophosphate sodium salt SP-8-pcpt-cgmps sodium salt

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S-(2-Hydroxy-5-nitrobenzyl)-6-thioguanosine 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt 7-Methyl-6-thioguanosine

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8-THIOGUANOSINE 8-MERCAPTOGUANOSINE 8-MERCAPTOGUANOSINE HYDRATE 8-Mercapto-7,8-dihydroguanosin Nsc79216 7,8-dihydro-8-thioxoguanosine SQ 12760 8-Tio-Guanosine Guanosine, 7,8-dihydro-8-thioxo- 8-SH-Guo 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-sulfanylidene-3,7-dihydropurin-6-one 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-8,9-dihydro-1H-purin-6(7H)-one 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-1,7,8,9-tetrahydro-6H-purin-6-one 26001-38-7 C10H13N5O5S Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents BioChemical