ChemicalBook >> CAS DataBase List >>5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium structure

CAS No.: 54260-72-9

Chemical Name:: 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium

Synonyms: 13-Methylberberine;13-Methylberberinium Chlorid;13-Methylberberine (chloride);13-Methylberberine chloride, 10 mM in DMSO;13-methylberberine/13-Methylberberine chloride;2,3-(Methylenedioxy)-9,10-dimethoxy-13-methyl-5H,6H-dibenzo[a,g]quinolizin-7-ium;9,10-Dimethoxy-13-methyl-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium;9,10-Dimethoxy-13-methyl-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride;inhibit,Inhibitor,13 Methylberberine chloride,13Methylberberine chloride,Interleukin Related,13-Methylberberinium

CBNumber:: CB82266822

Molecular Formula:: C21H20ClNO4

Molecular Weight:: 385.8408

MDL Number:: MFCD32197205

MOL File:: 54260-72-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

Product description	Number	Pack Size	Price
13-Methylberberine (chloride) ≥98%	21154	1mg	$60
13-Methylberberine (chloride) ≥98%	21154	5mg	$255
13-Methylberberine (chloride) ≥98%	21154	10mg	$451
13-Methylberberine chloride	ECA26072	1mg	$250
13-Methylberberine chloride	ECA26072	5mg	$438.55
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5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Properties

Melting point	198-200 °C
storage temp.	Store at -20°C
solubility	Water: 1 mg/ml
form	A crystalline solid
color	Light yellow to yellow

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21154	13-Methylberberine (chloride) ≥98%	54260-72-9	1mg	$60	2026-04-30	Buy
Cayman Chemical	21154	13-Methylberberine (chloride) ≥98%	54260-72-9	5mg	$255	2026-04-30	Buy
Cayman Chemical	21154	13-Methylberberine (chloride) ≥98%	54260-72-9	10mg	$451	2026-04-30	Buy
Biosynth	ECA26072	13-Methylberberine chloride	54260-72-9	1mg	$250	2026-06-04	Buy
Biosynth	ECA26072	13-Methylberberine chloride	54260-72-9	5mg	$438.55	2026-06-04	Buy

Product number	Packaging	Price	Buy
21154	1mg	$60	Buy
21154	5mg	$255	Buy
21154	10mg	$451	Buy
ECA26072	1mg	$250	Buy
ECA26072	5mg	$438.55	Buy

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Chemical Properties,Uses,Production

Description

13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine . Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity. 13-MB has improved antibacterial activity against S. aureus (MIC = 125 μg/ml) and improved antitumor activity with a mean GI₅₀ value of 11.7 μM, as compared to berberine. 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.

Uses

13-Methylberberinium Chloride can be used to treat and prevent immunoinflammatory dermal disorders. It can also be used in synthesis to result in derivatives that can be used to treat nerve diseases and anti-infective agents.

References

[1] YIT-LAI CHOW F S Mami Sogame. 13-Methylberberine, a berberine analogue with stronger anti-adipogenic effects on mouse 3T3-L1 cells[J]. Scientific Reports, 2016, 6 1. DOI: 10.1038/srep38129
[2] WEIJIA KONG. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins[J]. Nature Medicine, 2004, 10 12: 1344-1351. DOI: 10.1038/nm1135
[3] K IWASA . Antibacterial activity and structure-activity relationships of berberine analogs[J]. European Journal of Medicinal Chemistry, 1996, 31 6: Pages 469-478. DOI: 10.1016/0223-5234(96)85167-1
[4] KINUKO IWASA. In Vitro Cytotoxicity of the Protoberberine-Type Alkaloids[J]. Journal of Natural Products , 2001, 64 7: 896-898. DOI: 10.1021/np000554f
[5] DONG-UNG LEE . Effects of 13-alkyl-substituted berberine alkaloids on the expression of COX-II, TNF-α, iNOS, and IL-12 production in LPS-stimulated macrophages[J]. Life sciences, 2003, 73 11: Pages 1401-1412. DOI: 10.1016/s0024-3205(03)00435-1

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Preparation Products And Raw materials

Raw materials

Preparation Products

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Suppliers

Global( 66)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3618	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +86-18080483897	sales@biopurify.com	China	4616	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3861	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Henan Alfa Chemical Co., Ltd	+8618339805032	sale03@alfachem.cn	China	9811	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Aladdin Scientific		tp@aladdinsci.com	United States	52906	58
Mensura Group Limited	18780014153	1058503172@qq.com	China	2900	58
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Henan Alfa Chemical Co., Ltd	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Mensura Group Limited	58
Shandong Xiya Chemical Co., Ltd	57

View Lastest Price from 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	13-Methylberberine chloride 54260-72-9	$62.00-172.00		99.85%	10g	TargetMol Chemicals Inc.

13-Methylberberine chloride
54260-72-9
$62.00-172.00
99.85%
TargetMol Chemicals Inc.

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Spectrum

5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium(54260-72-9)¹HNMR

54260-72-9(5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium)Related Search:

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2,3-(Methylenedioxy)-9,10-dimethoxy-13-methyl-5H,6H-dibenzo[a,g]quinolizin-7-ium 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium 9,10-Dimethoxy-13-methyl-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium 13-Methylberberine (chloride) 13-Methylberberinium Chlorid 13-methylberberine/13-Methylberberine chloride inhibit,Inhibitor,13 Methylberberine chloride,13Methylberberine chloride,Interleukin Related,13-Methylberberinium 9,10-Dimethoxy-13-methyl-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride 13-Methylberberine chloride, 10 mM in DMSO 13-Methylberberine 54260-72-9