3-Bromo-5-methoxyphenol
- CAS No.
- 855400-66-7
- Chemical Name:
- 3-Bromo-5-methoxyphenol
- Synonyms
- 855400-66-7;3-Bromo-5-methoxyphenol;Phenol, 3-bromo-5-methoxy-;3-Bromo-5-methoxyphenol 97%;3-bromo-5-methoxybenzenephenol;3-hydroxy-5-methoxybromobenzene
- CBNumber:
- CB82513232
- Molecular Formula:
- C7H7BrO2
- Molecular Weight:
- 203.03
- MDL Number:
- MFCD12405420
- MOL File:
- 855400-66-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2909500090 |
3-Bromo-5-methoxyphenol price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FJB40066 | 3-Bromo-5-methoxyphenol | 855400-66-7 | 10g | $472 | 2026-06-04 | Buy |
| Apolloscientific | OR399011 | 3-Bromo-5-methoxyphenol 99% | 855400-66-7 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR399011 | 3-Bromo-5-methoxyphenol 99% | 855400-66-7 | 1g | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR399011 | 3-Bromo-5-methoxyphenol 99% | 855400-66-7 | 5g | $160 | 2026-06-04 | Buy |
| Apolloscientific | OR399011 | 3-Bromo-5-methoxyphenol 99% | 855400-66-7 | 25g | $629 | 2026-06-04 | Buy |
3-Bromo-5-methoxyphenol Chemical Properties, Uses, Production
Synthesis
20469-65-2
855400-66-7
(1a) Synthesis of 3-bromo-5-methoxyphenol: Commercially available 1-bromo-3,5-dimethoxybenzene (18.74 g, 86.3 mmol) was dissolved in 1-methyl-2-pyrrolidinone (100 mL), and sodium methanethiol (6.74 g, 96.2 mmol) was added. The reaction mixture was stirred at 100 °C for 3 h under nitrogen protection. After completion of the reaction, the reaction solution was cooled to room temperature, acidified by adding 1N hydrochloric acid (200 mL) and extracted with ether (500 mL). The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 20%-25% gradient) to afford the target compound 3-bromo-5-methoxyphenol (15.03 g, 86% yield) as a white solid.1H-NMR (CDCl3, 400 MHz) δ: 3.77 (3H, s), 4.82 (1H, s), 6.33 (1H, s), 6.33 (1H, s). 6.33 (1H, t, J = 2.4 Hz), 6.61 (1H, t, J = 2.0 Hz), 6.66 (1H, t, J = 2.0 Hz).
References
[1] Patent: EP2239253, 2010, A1. Location in patent: Page/Page column 44
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 3, p. 426 - 429
[3] Tetrahedron Letters, 2018, vol. 59, # 17, p. 1670 - 1673
[4] Patent: WO2007/34325, 2007, A1. Location in patent: Page/Page column 68
[5] Patent: US2011/105562, 2011, A1. Location in patent: Page/Page column 18
3-Bromo-5-methoxyphenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Chengdu Firster Pharmaceutical Co., Ltd. | 028-87078428 028-87074958 | chengzhenyong@cdfirster.com | China | 2580 | 60 |
| Xinyanhe Pharmatech Co.,Ltd | 0519-85252752 15366845260 | taihuaren@vip.163.com | China | 1033 | 58 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
