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2-chloroethanesulfonyl chloride

2-chloroethanesulfonyl chloride Structure
2-chloroethanesulfonyl chloride structure
CAS No.
1622-32-8
Chemical Name:
2-chloroethanesulfonyl chloride
Synonyms
oroethanesuL;2-chloroethanesulfochloride;2-chloroethylsulfonylchloride;2-chloro-ethanesulfonylchlorid;2-CHLOROETHANESULFONYL CHLORIDE;2-chloroethanesulfochloride[qr];2-CHLOROETHANESULPHONYL CHLORIDE;(2-chloroethyl)sulphonyl chloride;beta-chloroethanesulfonylchloride;2-chloroethylsulfonylchloride[qr]
CBNumber:
CB8257215
Molecular Formula:
C2H4Cl2O2S
Molecular Weight:
163.02
MDL Number:
MFCD00007461
MOL File:
1622-32-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:21:45
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2-chloroethanesulfonyl chloride Properties

Melting point 3 °C
Boiling point 84-86 °C15 mm Hg(lit.)
Density 1.56 g/mL at 25 °C(lit.)
vapor pressure 15 mm Hg ( 84 °C)
refractive index n20/D 1.493(lit.)
Flash point >230 °F
storage temp. Refrigerator
form Liquid
color Clear slightly yellow to brown
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 1751202
InChI InChI=1S/C2H4Cl2O2S/c3-1-2-7(4,5)6/h1-2H2
InChIKey VHCSBTPOPKFYIU-UHFFFAOYSA-N
SMILES C(S(Cl)(=O)=O)CCl
CAS DataBase Reference 1622-32-8(CAS DataBase Reference)
FDA UNII AET6VQ5A3Q
EPA Substance Registry System 2-Chloro-ethanesulfonyl chloride (1622-32-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H314-H330-H335
Precautionary statements  P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T+
Risk Statements  22-26-34-36
Safety Statements  26-28-36/37/39-45-23
RIDADR  UN 3390 6.1/PG 1
WGK Germany  3
RTECS  KI8060000
F  10-19
TSCA  TSCA listed
HazardClass  8
PackingGroup  II
HS Code  29049090
Hazardous Substances Data 1622-32-8(Hazardous Substances Data)
Toxicity mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971.
Limited Quantities 100ml (liquid) or 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)
NFPA 704
0
4 0
W

2-chloroethanesulfonyl chloride price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 302325 2-Chloroethanesulfonyl chloride 96% 1622-32-8 5g $50.2 2026-04-30 Buy
Sigma-Aldrich 302325 2-Chloroethanesulfonyl chloride 96% 1622-32-8 25g $123 2026-04-30 Buy
TCI Chemical C1142 2-Chloroethanesulfonyl Chloride >95.0%(GC)(T) 1622-32-8 25g $52 2026-04-30 Buy
TCI Chemical C1142 2-Chloroethanesulfonyl Chloride >95.0%(GC)(T) 1622-32-8 100g $171 2026-04-30 Buy
Usbiological 269180 2-Chloroethanesulfonyl chloride Asreported 1622-32-8 25g $389 2026-06-03 Buy
Product number Packaging Price Buy
302325 5g $50.2 Buy
302325 25g $123 Buy
C1142 25g $52 Buy
C1142 100g $171 Buy
269180 25g $389 Buy

2-chloroethanesulfonyl chloride Chemical Properties, Uses, Production

Chemical Properties

CLEAR SLIGHTLY YELLOW TO BROWN LIQUID

Uses

2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.

Application

As a precursor of the bis-electrophilic synthon vinylsulfonyl chloride, 2-chloroethanesulfonyl chloride can react with a wide range of bis-nucleophilic synthons, such as substituted 2-amino alcohols, to generate 7-membered sultams. This compound can be used in lieu of vinylsulfonyl chloride via a domino elimination– amidation reaction[1-2].

General Description

A liquid. Density 1.56 g / cm3. Flash point exceeds 230°F.

Air & Water Reactions

Reacts with water to produce corrosive and toxic gaseous hydrogen chloride.

Reactivity Profile

2-CHLOROETHANESULFONYL CHLORIDE is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

References

[1] Qin Zang. “Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol.” Heterocycles 86 2 (2012).
[2] Victor O Rogachev, Peter Metz. “Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides.” Nature Protocols 1 6 (2007): 3076–3087.

2-chloroethanesulfonyl chloride synthesis

1562-00-1
1622-32-8
Synthesis of 2-chloroethanesulfonyl chloride from Sodium isethionate

2-chloroethanesulfonyl chloride Preparation Products And Raw materials

Raw materials

Phosphorothioic acid, S-(2-chloroethyl) O,O-diethyl ester Sodium isethionate 2-Hydroxyethanesulphonic acid 2-Chloroethylamine hydrochloride 2,2'-Thiodiethanol
2-Mercaptoethanol

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Preparation Products

Sodium ethylenesulphonate N-(3-methoxyphenyl)-2-morpholin-4-yl-2-oxo-acetamide Ethenesulfonic acid, 1-methylethyl ester EthenesulfonaMide, N,N-bis(phenylMethyl) 1-Piperazinecarboxylic acid, 4-(ethenylsulfonyl)-, phenylmethyl ester
N-benzylethenesulfonamide 1-(Vinylsulfonyl)piperidine

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2-chloroethanesulfonyl chloride Suppliers

Global Suppliers ( 229)
Supplier Tel Email Country ProdList Advantage
Chongqing Botao Biotechnology Co., LTD 15223382610 danny@chemdad.com China 2030 58
Shaanxi Weiyu New Materials Co., Ltd 13772052144 13772052144 308828748@qq.com China 3000 58
Anyang Hongmeng New Materials Co., Ltd 0372-19588588067 19588588067 19588588067@163.com China 2963 58
Taizhou Xinhongchuan New Material Co., Ltd 18651157028 18651157028 2579548755@qq.com China 1365 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Beijing Donghualituo Techonlogy Development Co.,Ltd. 010-88425576 sales@dhltchem.com China 793 59
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Supplier Advantage
Chongqing Botao Biotechnology Co., LTD 58
Shaanxi Weiyu New Materials Co., Ltd 58
Anyang Hongmeng New Materials Co., Ltd 58
Taizhou Xinhongchuan New Material Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Beijing Donghualituo Techonlogy Development Co.,Ltd. 59
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81

View Latest Price from 2-chloroethanesulfonyl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLOROETHANESULFONYL CHLORIDE pictures 2026-07-21 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
 10kg 97% 20tons Hubei Lidu New Material Technology Co., Ltd
2-CHLOROETHANESULFONYL CHLORIDE pictures 2020-01-09 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

2-chloroethanesulfonyl chloride Spectrum

2-CHLOROETHANESULFONYL CHLORIDE(1622-32-8)MS2-CHLOROETHANESULFONYL CHLORIDE(1622-32-8)1HNMR2-CHLOROETHANESULFONYL CHLORIDE(1622-32-8)13CNMR2-CHLOROETHANESULFONYL CHLORIDE(1622-32-8)IR12-CHLOROETHANESULFONYL CHLORIDE(1622-32-8)Raman

1622-32-8 (2-chloroethanesulfonyl chloride) Related Search:

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2-Chloroethane-1-sulfonic acid chloride 2-Chloroethanesulfonic acid chloride 2-Chloroethanesulfonyl Chloride, 95.0%(GC&T 2-CHLOROETHANESULFONYL CHLORIDE 2-CHLOROETHANESULPHONYL CHLORIDE 2-CHLORO-1-ETHANESULFONYL CHLORIDE beta-chloroethanesulfonylchloride beta-chloroethanesulfonylchloride[qr] ethanesulfonylchloride,2-chloro-[qr] (2-chloroethyl)sulphonyl chloride 2-Chloroethanesulfonyl chloride, 98+% 2-CHLOROETHANESULFONYL CHLORIDE 95+% 2-Chloroethanesulfonoic acid chlorohydride oroethanesuL 2-chloroethanesulfochloride 2-chloroethanesulfochloride[qr] 2-chloro-ethanesulfonylchlorid 2-chloroethanesulfonylchloride[qr] 2-chloroethylsulfonylchloride 2-chloroethylsulfonylchloride[qr] 2-Chloroethanesulfonyl Chloride > Ethanesulfonyl chloride, 2-chloro- 1622-32-8 C2H4S2O2Cl2 C2H4O2Cl2S ClCH2CH2SO2Cl C2H4Cl2O2S SULFONYL CHLORIDE Sulfonyl Halides Synthetic Reagents Sulfur Compounds Others Sulfur Compounds (for Synthesis) Building Blocks Protecting and Derivatizing Reagents Protection and Derivatization Organic Building Blocks Sulfur Compounds (for Synthesis) Synthetic Organic Chemistry Others Organic Building Blocks Sulfonyl Halides Sulfur Compounds Protecting and Derivatizing Reagents Protection and Derivatization