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3-chloro-2-methyl-5-nitro-pyridine

CAS No.
51984-62-4
Chemical Name:
3-chloro-2-methyl-5-nitro-pyridine
Synonyms
3-chloro-2-methyl-5-nitro-pyridine;Pyridine, 3-chloro-2-methyl-5-nitro-
CBNumber:
CB82742555
Molecular Formula:
C6H5ClN2O2
Molecular Weight:
172.57
MDL Number:
MFCD16556270
MOL File:
51984-62-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:06:52
Product description Number Pack Size Price
3-Chloro-2-methyl-5-nitropyridine BCA98462 5g $312.5
3-Chloro-2-methyl-5-nitropyridine 98% OR345535 250mg $22
3-Chloro-2-methyl-5-nitropyridine 98% OR345535 1g $32
3-Chloro-2-methyl-5-nitropyridine 98% OR345535 25g $294
3-Chloro-2-methyl-5-nitropyridine 153948 5.00g $1564

3-chloro-2-methyl-5-nitro-pyridine Properties

Boiling point 248.7±35.0 °C(Predicted)
Density 1.406±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka -0.37±0.20(Predicted)
Appearance Brown to reddish brown Solid
InChI InChI=1S/C6H5ClN2O2/c1-4-6(7)2-5(3-8-4)9(10)11/h2-3H,1H3
InChIKey KEQYIUZGVFBSNL-UHFFFAOYSA-N
SMILES C1(C)=NC=C([N+]([O-])=O)C=C1Cl

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

3-chloro-2-methyl-5-nitro-pyridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth BCA98462 3-Chloro-2-methyl-5-nitropyridine 51984-62-4 5g $312.5 2026-06-04 Buy
Apolloscientific OR345535 3-Chloro-2-methyl-5-nitropyridine 98% 51984-62-4 250mg $22 2026-06-04 Buy
Apolloscientific OR345535 3-Chloro-2-methyl-5-nitropyridine 98% 51984-62-4 1g $32 2026-06-04 Buy
Apolloscientific OR345535 3-Chloro-2-methyl-5-nitropyridine 98% 51984-62-4 25g $294 2026-06-04 Buy
Matrix Scientific 153948 3-Chloro-2-methyl-5-nitropyridine 51984-62-4 5.00g $1564 2026-05-18 Buy
Product number Packaging Price Buy
BCA98462 5g $312.5 Buy
OR345535 250mg $22 Buy
OR345535 1g $32 Buy
OR345535 25g $294 Buy
153948 5.00g $1564 Buy

3-chloro-2-methyl-5-nitro-pyridine Chemical Properties,Uses,Production

Synthesis

2,3-DICHLORO-5-NITROPYRIDINE

22353-40-8

Methylboronic acid

13061-96-6

3-chloro-2-methyl-5-nitro-pyridine

51984-62-4

General procedure for the synthesis of 3-chloro-2-methyl-5-nitropyridine from 2,3-dichloro-5-nitropyridine and methylboronic acid: Cesium carbonate (338 mg, 1.04 mmol), methylboronic acid (47 mg, 0.78 mmol) and tetrakis(triphenylphosphine)palladium (60 mg, 0.052 mmol) were sequentially added to a solution of 1,4-dioxane (3 mL) containing 2,3-dichloro-5-nitropyridine (191 mg, 1.00 mmol), protected by argon gas. -5-nitropyridine (191 mg, 1.00 mmol) to a solution of 1,4-dioxane (3 mL). The reaction mixture was stirred at 100 °C for 6 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, water (10 mL) was added and extracted with ethyl acetate (3 × 10 mL). The organic phases were combined, washed with saturated saline (10 mL) and dried over anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. Purification by column chromatography (eluent: petroleum ether/ethyl acetate = 5:1) afforded 3-chloro-2-methyl-5-nitropyridine (344 mg, 90% yield) as a pale yellow solid.

References

[1] Patent: EP2589592, 2018, B1. Location in patent: Paragraph 1190; 1191

22353-40-8
13061-96-6
51984-62-4
Synthesis of 3-chloro-2-methyl-5-nitro-pyridine from 2,3-DICHLORO-5-NITROPYRIDINE and Methylboronic acid

3-chloro-2-methyl-5-nitro-pyridine Preparation Products And Raw materials

3-chloro-2-methyl-5-nitro-pyridine Suppliers

Global( 33)Suppliers
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Shaanxi Dideu Medichem Co. Ltd
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LinkChem Technology Co., Ltd. 021-58950110 13124863828 sales@linkchem.cn China 2996 58
Sichuan BoYou Biotechnology Co., Ltd. 028-65791793 18140026355 568470422@qq.com China 9961 58

3-chloro-2-methyl-5-nitro-pyridine Spectrum

3-chloro-2-methyl-5-nitro-pyridine Pyridine, 3-chloro-2-methyl-5-nitro- 51984-62-4