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AF38469

AF38469 Structure
AF38469 structure
CAS No.
1531634-31-7
Chemical Name:
AF38469
Synonyms
CS-2561;AF38469;AF38469 ，S7478;AF38469 (AF-38469);AF38469, 10 mM in DMSO;inhibit,AF 38469,Neurotensin Receptor,Inhibitor,AF38469;2-[(6-Methyl-2-pyridyl)carbamoyl]-5-(trifluoromethyl)benzoic Acid;2-((6-Methylpyridin-2-yl)carbamoyl)-5-(trifluoromethyl)benzoic acid;Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)-
CBNumber:
CB82744892
Molecular Formula:
C15H11F3N2O3
Molecular Weight:
324.25
MDL Number:
MFCD28160694
MOL File:
1531634-31-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-18 07:23:31
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AF38469 Properties

Boiling point 392.3±42.0 °C(Predicted)
Density 1.448±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: Soluble; Ethanol: Soluble
form A solid
pka 2.83±0.36(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

AF38469 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 35530 AF38469 ≥98% 1531634-31-7 1mg $74 2026-04-30 Buy
Cayman Chemical 35530 AF38469 ≥98% 1531634-31-7 5mg $329 2026-04-30 Buy
Cayman Chemical 35530 AF38469 ≥98% 1531634-31-7 10mg $585 2026-04-30 Buy
Cayman Chemical 35530 AF38469 ≥98% 1531634-31-7 25mg $1094 2026-04-30 Buy
Biosynth GLC63431 AF38469 1531634-31-7 5mg $756.5 2026-06-04 Buy
Product number Packaging Price Buy
35530 1mg $74 Buy
35530 5mg $329 Buy
35530 10mg $585 Buy
35530 25mg $1094 Buy
GLC63431 5mg $756.5 Buy

AF38469 Chemical Properties, Uses, Production

Uses

AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.

in vivo

AF38469 (1 mg/kg; i.v.) has a low volume of distribution (blood volume of 0.7 L/kg) and low clearance (4.8 L/h/kg), and a half-life (t1/2) of 1.2 h in rat[1].

References

[1] Schroder TJ, et al. The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80. DOI:10.1016/j.bmcl.2013.11.046

AF38469 Preparation Products And Raw materials

Raw materials

Preparation Products

AF38469 Suppliers

Global Suppliers ( 65)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Artis Chemistry (Shanghai) Co. Ltd. 86-21-60936353 China 335 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Artis Biotech Co. Ltd. 18108108965 18108108965 sales@artisbio.com China 2503 58
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3853 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
Artis Chemistry (Shanghai) Co. Ltd. 58
Haoyuan Chemexpress Co., Ltd. 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Quality Control Solutions Ltd. 56
Shanghai Lollane Biological Technology Co.,Ltd. 55
Artis Biotech Co. Ltd. 58
Guangzhou QiYun Biotechnology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58

View Latest Price from AF38469 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AF38469 pictures 2026-07-17 AF38469
1531634-31-7
 $89.00-297.00 99.56% 10g TargetMol Chemicals Inc.
  • AF38469 pictures
  • AF38469
    1531634-31-7
  • $89.00-297.00
  • 99.56%
  • TargetMol Chemicals Inc.

AF38469 Spectrum

AF38469(1531634-31-7)1HNMR

1531634-31-7 (AF38469) Related Search:

2-(6-Methyl-2-pyridinyl)-5-(trifluoromethyl)-1H-isoindole-1,3(2H)-dione CHEMBRDG-BB 5636979 AF38469 TC 14012 hydrochloride JTE-013
DEVAZEPIDE

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AF38469 AF38469 (AF-38469) CS-2561 Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)- 2-((6-Methylpyridin-2-yl)carbamoyl)-5-(trifluoromethyl)benzoic acid inhibit,AF 38469,Neurotensin Receptor,Inhibitor,AF38469 2-[(6-Methyl-2-pyridyl)carbamoyl]-5-(trifluoromethyl)benzoic Acid AF38469, 10 mM in DMSO AF38469 ，S7478 1531634-31-7