ChemicalBook >> CAS DataBase List >>O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride structure

CAS No.: 57981-02-9

Chemical Name:: O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

Synonyms: PFBHA;O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine;PFBHA HCL;Nsc153392;FLOROX REAGENT;FLOROX(TM) REAGENT;TIMTEC-BB SBB003152;Pentafluorobenzylhydroxylamine;PENTAFLUOROBENZYLHYDROXYLAMINE HCL;(2,3,4,5,6-Pentafluorobenzyl)oxyamine

CBNumber:: CB8307815

Molecular Formula:: C7H5ClF5NO

Molecular Weight:: 249.57

MDL Number:: MFCD00012953

MOL File:: 57981-02-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:55:38

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O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride Properties

Melting point	227 °C (subl.)(lit.)
storage temp.	Inert atmosphere,Room Temperature
solubility	H₂O: 5%, clear
form	powder to crystal
color	White
PH	pH(5g/l, 25℃) : 2.0～3.0
Water Solubility	Soluble in water.
BRN	4031190
InChI	1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H
InChIKey	HVMVKNXIMUCYJA-UHFFFAOYSA-N
SMILES	Cl.NOCc1c(F)c(F)c(F)c(F)c1F
CAS DataBase Reference	57981-02-9(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P271-P280

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Risk Statements

36/37/38

Safety Statements

22-24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29280000

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		1

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	194484	O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride ≥98%	57981-02-9	250mg	$64.4	2026-04-30	Buy
Sigma-Aldrich	194484	O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride ≥98%	57981-02-9	1g	$174	2026-04-30	Buy
TCI Chemical	P0822	O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation] >98.0%(HPLC)(N)	57981-02-9	1g	$111	2026-04-30	Buy
TCI Chemical	P0822	O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation] >98.0%(HPLC)(N)	57981-02-9	5g	$419	2026-04-30	Buy
TRC	TRC-P227330-500MG	O-((Perfluorophenyl)methyl)hydroxylamine Hydrochloride	57981-02-9	500mg	$199	2026-06-03	Buy

Product number	Packaging	Price	Buy
194484	250mg	$64.4	Buy
194484	1g	$174	Buy
P0822	1g	$111	Buy
P0822	5g	$419	Buy
TRC-P227330-500MG	500mg	$199	Buy

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used in the preparation of oximes of steroids having keto group. It is used as a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin and a variety of aldehydes, ketones and acids. It is a versatile reagent utilized for the detection of carbonyl-containing compounds by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and other methods. As a derivatization reagent, it is also used for EC/LC analysis of keto-steroids and carbohydrates.

Uses

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:

In the preparation of oximes of steroids-bearing keto group.
As a derivatization reagent in the determination of thromboxane B₂, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.

It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.

General Description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

reaction suitability

reagent type: derivatization reagent
reaction type: Alkylations

Purification Methods

Recrystallise the salt from EtOH to form colourless leaflets. Drying the compound at high vacuum and elevated temperature will result in losses by sublimation. [Youngdale J Pharm Sci 65 625 1976, Wehner & Handke J Chromatog 177 237 1979, Nambara et al. give incorrect m as 115-116o J Chromatogr 114 81 1975.]

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride Preparation Products And Raw materials

Raw materials

Hexane Hydrazinium hydroxide solution N-Hydroxyphthalimide N,N-Dimethylformamide Acetone

Bromopentafluorobenzene Triethylamine Hydrogen bromide Tetrahydrofuran Diethyl ether

Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide

Magnesium N-Methylformanilide Sulfuric acid

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Preparation Products

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride Suppliers

Global( 205)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhengzhou Kingsfine Chemical Co., Ltd.	0371-56635027 13838252817	sales@kingsfine.com	China	100	62
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Nanjing Habo Medical Technology Co., Ltd.	13376080562 13376090521	sales@habotech.com	China	726	60
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64

Supplier	Advantage
Zhengzhou Kingsfine Chemical Co., Ltd.	62
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Nanjing Habo Medical Technology Co., Ltd.	60
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Nanjing Chemlin Chemical Co., Ltd	64

View Lastest Price from O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE 57981-02-9	$1.00	1kg	98%	100KG	Career Henan Chemical Co

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
57981-02-9
$1.00
98%
Career Henan Chemical Co

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride Spectrum

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE(57981-02-9)MS O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE(57981-02-9)¹HNMR O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE(57981-02-9)¹³CNMR O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE(57981-02-9)IR1

57981-02-9(O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride)Related Search:

2,3,4-Trifluorobenzyl alcohol O-Benzylhydroxylamine hydrochloride 2,5-Difluorobenzyl alcohol 3,4-Difluorobenzyl alcohol 1,2,3,5-Tetrafluorobenzene

2,3,4,5,6-Pentafluorobenzyl alcohol 2,3,4,5-Tetrafluorobenzyl alcohol 2,6-Difluorobenzyl alcohol 2,3-Difluorobenzyl alcohol 2,3,5-Trifluorobenzyl alcohol

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2-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE FLOROX REAGENT FLOROX(TM) REAGENT PFBHA HCL PENTAFLUOROBENZYLHYDROXYLAMINE HCL O-(PENTAFLUOROBENZYL)HYDROXYAMINE HYDROCHLORIDE O-(PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE O-PENTAFLUOROBENZYLHYDROXYLAMINE HYDROCHLORIDE IN PYRIDINE TIMTEC-BB SBB003152 0-(2,3,4,5,6-Pentafluorobenzyl) Hydroxylamine Hydrochloride O-(Pentafluorobenzyl)hydroxylamine hydrochloride 97% O-(2,3,4,5,6-pentafluorobenzyl)*hydroxylamine hyd O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYL- AMINE HYDROCHLORIDE, 99+% O-(2,3,4,5,6-PENTAFLUOROBENZYL)*HYDROXYL AMINE HYDRO O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHCl O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride 97% O-(Pentafluorobenzyl)hydroxylaminehydrochloride97% O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation] (2,3,4,5,6-Pentafluorobenzyl)oxyamine [(2,3,4,5,6-Pentafluorobenzyl)oxy]amine O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine O-(Pentafluorophenylmethyl)hydroxylamine Pentafluorobenzylhydroxylamine O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine·hydrochloric acid Pentafluorobenzylhydroxylamine·hydrochloride 1-[(Aminooxy)methyl]-2,3,4,5,6-pentafluorobenzene hydrochloride 2,3,4,5,6-Pentafluorobenzyloxyamine hydrochloride N-[(2,3,4,5,6-Pentafluorobenzyl)oxy]amine hydrochloride Nsc153392 O-[(2,3,4,5,6-Pentafluorophenyl)methyl]hydroxylamine hydrochloride O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride >=98% O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride, derivatization grade Hydroxylamine, O-[(2,3,4,5,6-pentafluorophenyl)methyl]-, hydrochloride (1:1) 6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99%, derivatization grade Method 556 PFBHA Reagent@15.0 mg/mL in Water O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHydrochloride[forOximePreparation]> O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride for GC derivatization O-[(2,3,4,5,6-pentafluorophenyl)methyl]hydroxylamine O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride o-((Perfluorophenyl)methyl)hydroxylamine HCl PFBHA O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride 57981-02-9 C7H5ClF5NO C7H4F5NO C6F5CH2ONH2HCl C7H4F5NOHCl C7H4F5NOClH Biochemicals and Reagents Building Blocks BioChemical Nitrogen Compounds Luminescent Compounds/Detection Organic Building Blocks Derivatization agents Boronic Acid, etc. (GC Derivatizing Reagents) GC Derivatizing Reagents