2,4-Difluorobenzyl alcohol
- CAS No.
- 56456-47-4
- Chemical Name:
- 2,4-Difluorobenzyl alcohol
- Synonyms
- RARECHEM AL BD 0213;2,4-Difluorobenzyl a;3,4-difluorobenzyl alcoho;2,4-DIFLURO BENZYL ALCOHOL;2,4-DIFLUOROBENZYL ALCOHOL;2,4-Difluorobenzenemethanol;2,4-DifluorobenzylAlcohol>2,4-Difluorobenzylalcohol98%;(2,4-DIFLUORO-PHENYL)-METHANOL;Benzenemethanol, 2,4-difluoro-
- CBNumber:
- CB8361664
- Molecular Formula:
- C7H6F2O
- Molecular Weight:
- 144.12
- MDL Number:
- MFCD00009983
- MOL File:
- 56456-47-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 52 °C |
|---|---|
| Density | 1.29 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 194 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 13.82±0.10(Predicted) |
| color | Colorless to Light orange to Yellow |
| Specific Gravity | 1.290 |
| BRN | 2501944 |
| InChI | InChI=1S/C7H6F2O/c8-6-2-1-5(4-10)7(9)3-6/h1-3,10H,4H2 |
| InChIKey | NIJZBWHOHNWJBX-UHFFFAOYSA-N |
| SMILES | C1(CO)=CC=C(F)C=C1F |
| CAS DataBase Reference | 56456-47-4(CAS DataBase Reference) |
| FDA UNII | SVX5XQB2MB |
| NIST Chemistry Reference | 2,4-Difluorobenzyl alcohol(56456-47-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H227-H315-H319 | |||||||||
| Precautionary statements | P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29062990 | |||||||||
| NFPA 704 |
|
2,4-Difluorobenzyl alcohol price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D1838 | 2,4-Difluorobenzyl Alcohol >96.0%(GC) | 56456-47-4 | 10g | $86 | 2026-04-30 | Buy |
| Apolloscientific | PC2730 | 2,4-Difluorobenzyl alcohol 98% | 56456-47-4 | 25g | $54 | 2026-06-04 | Buy |
| Activate Scientific | AS24778 | 2,4-Difluorobenzyl Alcohol 97% | 56456-47-4 | 5g | $24 | 2026-06-04 | Buy |
| Activate Scientific | AS24778 | 2,4-Difluorobenzyl Alcohol 97% | 56456-47-4 | 25g | $45 | 2026-06-04 | Buy |
| Activate Scientific | AS24778 | 2,4-Difluorobenzyl Alcohol 97% | 56456-47-4 | 100g | $168 | 2026-06-04 | Buy |
2,4-Difluorobenzyl alcohol Chemical Properties, Uses, Production
Chemical Properties
CLEAR COLORLESS LIQUID
Uses
2,4-Difluorobenzyl alcohol is used as pharmaceutical, pesticide, and liquid crystal material intermediates.
Synthesis
To a stirred solution of 2,4-difluorobenzaldehyde (500 mg, 3.52 mmol) in CH3OH (8 mL) was added NaBH4(266 mg, 7.04 mmol) portion wise at 0° C., and the reaction mixture was stirred at 0° C. for 1 h. After completion of the reaction (by TLC), CH3OH was removed under reduced pressure, diluted with ice-cold H2O (40 mL) and extracted with EtOAc (2.x.20 mL). The combined organic layers were washed with H2O (40 mL) and brine (40 mL), dried over anhydrous Na2SO4and concentrated under reduced pressure to obtain the crude material. Purification by silica gel column chromatography eluting with 10percent EtOAc/hexanes afforded 2,4-Difluorobenzyl alcohol (450 mg, 3.12 mmol, 88percent) as colorless liquid. 1H NMR (200 MHz, CDCl3): δ 7.45-7.33 (m, 1H), 6.83-6.75 (m, 2H), 4.72 (s, 2H), 1.79 (br s, OH).
References
[1] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 564 - 576
[2] Organometallics, 2015, vol. 34, # 20, p. 5175 - 5182
[3] Patent: US2012/329788, 2012, A1. Location in patent: Page/Page column 26
[4] European Journal of Inorganic Chemistry, 2015, vol. 2015, # 16, p. 2732 - 2743
[5] Dalton Transactions, 2016, vol. 45, # 45, p. 18133 - 18141
2,4-Difluorobenzyl alcohol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 2,4-Difluorobenzyl alcohol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 2,4-Difluorobenzyl alcohol
56456-47-4
|
$2.00-5.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2019-07-06 | 2,4-Difluorobenzyl alcohol
56456-47-4
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 2,4-Difluorobenzyl alcohol
56456-47-4
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2,4-Difluorobenzyl alcohol
56456-47-4
- $1.00
- 99%
- Career Henan Chemical Co
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