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2-Fluoro-4-(trifluoromethyl)phenylboronic acid

2-Fluoro-4-(trifluoromethyl)phenylboronic acid Structure
2-Fluoro-4-(trifluoromethyl)phenylboronic acid structure
CAS No.
503309-11-3
Chemical Name:
2-Fluoro-4-(trifluoromethyl)phenylboronic acid
Synonyms
AKOS BRN-0670;2-Fluoro-4-(Trifluoromethyl)Ph;4-Borono-3-fluorobenzotrifluoride;Fluoro-4-(trifluoroMethyl)phenylboroni;2-Fluoro-4-(trifluoroMethyl)boronic acid;2-fluoro-4-trifluoromethphenylboronic acid;4-trifluoroMethyl-2-fluorophenylboronic acid;2-Fluoro-4-(trifluoromethyl)phenylboronicaci;2-Fluoro-4-(trifluoromethyl)phenylboronic acid;2-FLUORO-4-(TRIFLUOROMETHYL)BENZENEBORONIC ACID
CBNumber:
CB8321334
Molecular Formula:
C7H5BF4O2
Molecular Weight:
207.92
MDL Number:
MFCD03094995
MOL File:
503309-11-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:38
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2-Fluoro-4-(trifluoromethyl)phenylboronic acid Properties

Melting point 113-115°C
Boiling point 251.9±50.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form powder to crystal
pka 7.62±0.58(Predicted)
color White to Light yellow
InChI InChI=1S/C7H5BF4O2/c9-6-3-4(7(10,11)12)1-2-5(6)8(13)14/h1-3,13-14H
InChIKey SSFSVKVWAURAAM-UHFFFAOYSA-N
SMILES B(C1=CC=C(C(F)(F)F)C=C1F)(O)O
CAS DataBase Reference 503309-11-3(CAS DataBase Reference)
UNSPSC Code 12352106

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22-36
Safety Statements  26-36/37/39-36-37
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29319090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
NFPA 704
0
2 0

2-Fluoro-4-(trifluoromethyl)phenylboronic acid price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0816 2-Fluoro-4-(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 503309-11-3 1g $82 2024-03-01 Buy
TCI Chemical F0816 2-Fluoro-4-(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 503309-11-3 5g $262 2024-03-01 Buy
Biosynth FF105416 [2-fluoro-4-(trifluoromethyl)phenyl]boronic Acid 503309-11-3 0.1kg $900 2026-06-04 Buy
Biosynth FF105416 [2-fluoro-4-(trifluoromethyl)phenyl]boronic Acid 503309-11-3 0.05kg $900 2026-06-04 Buy
Biosynth FF105416 [2-fluoro-4-(trifluoromethyl)phenyl]boronic Acid 503309-11-3 0.025kg $900 2026-06-04 Buy
Product number Packaging Price Buy
F0816 1g $82 Buy
F0816 5g $262 Buy
FF105416 0.1kg $900 Buy
FF105416 0.05kg $900 Buy
FF105416 0.025kg $900 Buy

2-Fluoro-4-(trifluoromethyl)phenylboronic acid Chemical Properties, Uses, Production

Chemical Properties

White crystalline powder

Uses

2-Fluoro-4-trifluoromethylphenylboronic acid

Synthesis

To a stirred solution of 5-bromo-2-(methylthio)pyrimidine (950 mg, 4.63 mmol) in DMF (5 mL) was added 4,4,4,4,5,5,5,5-octamethyl-2,2-bis(1,3,2-dioxaborolane) (1.77 g, 6.95 mmol), potassium acetate (1.36 g , 13.90 mmol) and palladium diacetate (104 mg, 0.463 mol). The resulting suspension was degassed with argon for 15 minutes and then heated at 85C overnight. The reaction mixture was allowed to cool to room temperature. EtOAc (10 mL) was added to the reaction mixture and the reaction mixture was washed with brine (15 mLx3). The organic phase was dried (MgSO4), filtered and concentrated to give 2-methylthiopyrimidine-5-boronic acid pinacol ester.

2-Fluoro-4-(trifluoromethyl)phenylboronic acid synthesis

5419-55-6
401-80-9
503309-11-3
Synthesis of 2-Fluoro-4-(trifluoromethyl)phenylboronic acid from Triisopropyl borate and 3-Fluorobenzotrifluoride

2-Fluoro-4-(trifluoromethyl)phenylboronic acid Preparation Products And Raw materials

Raw materials

Triisopropyl borate 3-Fluorobenzotrifluoride

Preparation Products

Pyridine, 4-[2-fluoro-4-(trifluoromethyl)phenyl]-

2-Fluoro-4-(trifluoromethyl)phenylboronic acid Suppliers

Global Suppliers ( 257)
Supplier Tel Email Country ProdList Advantage
Hebei Maison Chemical Co.,Ltd. 155-11852758; 18408670720 ruby@maisonchem.com.cn China 687 58
GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD 020-86211473 13925088720 linda@aanpharm.com China 3641 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Hebei Maison Chemical Co.,Ltd. 58
GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

View Latest Price from 2-Fluoro-4-(trifluoromethyl)phenylboronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID pictures 2026-09-02 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
503309-11-3
 $1.20-34.00 1kg 99% Henan Fengda Chemical Co., Ltd
2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID pictures 2025-06-25 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
503309-11-3
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID pictures 2025-06-20 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
503309-11-3
 1kg 99.50% 20tons Hebei Yanxi Chemical Co., Ltd.

2-Fluoro-4-(trifluoromethyl)phenylboronic acid Spectrum

2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID(503309-11-3)1HNMR2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLBORONIC ACID(503309-11-3)FT-IR

503309-11-3 (2-Fluoro-4-(trifluoromethyl)phenylboronic acid) Related Search:

5-Fluoro-2-(trifluoromethyl)phenylboronic acid 3-Fluoro-4-trifluoromethyl-phenylboronic acid 2-Fluoro-3-(trifluoromethyl)phenylboronic acid 4-Fluoro-3-(trifluoromethyl)phenylboronic acid 2-Fluoro-5-(trifluoromethyl)phenylboronic acid
2-Fluoro-4-(trifluoromethyl)phenylboronic acid 2-Fluoro-4-trifluoromethylphenylboronic acid, pinacol ester 2-Bromo-5-fluorobenzotrifluoride 3-Fluoro-4-(trifluoromethyl)phenylboronic acid pinacol ester 4-Fluoro-3-(trifluoromethyl)phenylboronic acid pinacol ester
2-Fluoro-4-methylphenylboronic acid 4-Difluoromethyl-phenylboronic acid 4-Trifluoromethylphenylboronic acid

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4-Borono-3-fluorobenzotrifluoride 2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid (contains varying aMounts of Anhydride) 4-trifluoroMethyl-2-fluorophenylboronic acid 2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid  2-Fluoro-4-(trifluoroMethyl)boronic acid BORONICACID, B-[2-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]- Fluoro-4-(trifluoroMethyl)phenylboroni 2-FLUORO-4-(TRIFLUOROMETHYL)BENZENEBORONIC ACID AKOS BRN-0670 2-Fluoro-4-(Trifluoromethyl)Ph 2-fluoro-4-trifluoromethphenylboronic acid Boronic acid, [2-fluoro-4-(trifluoromethyl)phenyl]- 2-Fluoro-4-(trifluoromethyl)phenylboronicaci B-[2-Fluoro-4-(trifluoromethyl)phenyl]boronic acid 2-Fluoro-4-(trifluoromethyl)phenylboronic acid 503309-11-3 C7H5O2BF4 Boronic Acid blocks BoronicAcids Aryl Organoborons